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The map label for this gene is ribH2

Identifier: 16125608

GI number: 16125608

Start: 1512605

End: 1513069

Strand: Direct

Name: ribH2

Synonym: CC_1359

Alternate gene names: 16125608

Gene position: 1512605-1513069 (Clockwise)

Preceding gene: 16125607

Following gene: 16125609

Centisome position: 37.66

GC content: 65.81

Gene sequence:

>465_bases
ATGGTTGAAGACAAAATCCGCCTGCTGATCGTGGAGGGCCGAAGCCATTCGGGGATCTCCGACGAACTGCTGCGCGGAGC
CACCCAAGCCATCGAGGCGCGGGGCGCCGATTACGACGTGATCACCGTGTCGAACGCGCTGCAGATTCCGACCGTGATCG
CCATGGCTGAGGATGCCGGGCACCGTCCGGTCGGCGTGCGCTATGATGGCTATGTCGCCCTTGGCGTGGTGATCCGCGGC
GAAACCTACCATTTCGAACTCGTCGCCAACGAGACCGCTCGTGGCTTGCAGGACCTTGGCGTGGCCAAGCGTCTGCCGAT
CGGATTCGGCGTGCTGGCCGTTGATGAAGAGGCCCAGGCCCTGAGCCGCGCCCGGGTCAGCGAAGGTGATCGCGGCGGCG
CGGCCGCTAAGGCCTGCCTGGAGACCATCGGCCTGAAGCGCCAACTGCTGGGGCAGGCCCGATGA

Upstream 100 bases:

>100_bases
AGGGTCTGAGCGACGGCGGTGAAGAAGAGCTATAGTCCGTTAATCCTGATGTGTGTTTGTAGGGGCGCGCGGCGCGCGTG
CCCGTGGAGAGTTGAGCTAG

Downstream 100 bases:

>100_bases
GCGGCAACCGTATCCAACCGCGCTCCGTTGCGCGTCTCGCCGCCGTCCAGGCGCTGTATCAGATGGAAGTCTCGGGCGCC
GGCGTCGATTCGGTGATCCG

Product: riboflavin synthase subunit beta

Products: NA

Alternate protein names: DMRL synthase 2; Lumazine synthase 2; Riboflavin synthase 2 beta chain

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVEDKIRLLIVEGRSHSGISDELLRGATQAIEARGADYDVITVSNALQIPTVIAMAEDAGHRPVGVRYDGYVALGVVIRG
ETYHFELVANETARGLQDLGVAKRLPIGFGVLAVDEEAQALSRARVSEGDRGGAAAKACLETIGLKRQLLGQAR

Sequences:

>Translated_154_residues
MVEDKIRLLIVEGRSHSGISDELLRGATQAIEARGADYDVITVSNALQIPTVIAMAEDAGHRPVGVRYDGYVALGVVIRG
ETYHFELVANETARGLQDLGVAKRLPIGFGVLAVDEEAQALSRARVSEGDRGGAAAKACLETIGLKRQLLGQAR
>Mature_154_residues
MVEDKIRLLIVEGRSHSGISDELLRGATQAIEARGADYDVITVSNALQIPTVIAMAEDAGHRPVGVRYDGYVALGVVIRG
ETYHFELVANETARGLQDLGVAKRLPIGFGVLAVDEEAQALSRARVSEGDRGGAAAKACLETIGLKRQLLGQAR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=147, Percent_Identity=32.6530612244898, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324429, Length=142, Percent_Identity=31.6901408450704, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB2_CAUCR (Q9A8J4)

Other databases:

- EMBL:   AE005673
- PIR:   H87417
- RefSeq:   NP_420172.1
- ProteinModelPortal:   Q9A8J4
- SMR:   Q9A8J4
- GeneID:   941698
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_1359
- NMPDR:   fig|190650.1.peg.1352
- TIGR:   CC_1359
- HOGENOM:   HBG311126
- OMA:   SSRALMD
- ProtClustDB:   PRK00061
- BRENDA:   2.5.1.9
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 16393; Mature: 16393

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEDKIRLLIVEGRSHSGISDELLRGATQAIEARGADYDVITVSNALQIPTVIAMAEDAG
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCC
HRPVGVRYDGYVALGVVIRGETYHFELVANETARGLQDLGVAKRLPIGFGVLAVDEEAQA
CCCCCEEECCEEEEEEEEECCEEEEEEEECCHHHHHHHCCCHHCCCCCCEEEEECHHHHH
LSRARVSEGDRGGAAAKACLETIGLKRQLLGQAR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVEDKIRLLIVEGRSHSGISDELLRGATQAIEARGADYDVITVSNALQIPTVIAMAEDAG
CCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCC
HRPVGVRYDGYVALGVVIRGETYHFELVANETARGLQDLGVAKRLPIGFGVLAVDEEAQA
CCCCCEEECCEEEEEEEEECCEEEEEEEECCHHHHHHHCCCHHCCCCCCEEEEECHHHHH
LSRARVSEGDRGGAAAKACLETIGLKRQLLGQAR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647