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The map label for this gene is nrdR

Identifier: 16125607

GI number: 16125607

Start: 1512066

End: 1512539

Strand: Direct

Name: nrdR

Synonym: CC_1358

Alternate gene names: 16125607

Gene position: 1512066-1512539 (Clockwise)

Preceding gene: 16125606

Following gene: 16125608

Centisome position: 37.64

GC content: 61.81

Gene sequence:

>474_bases
ATGCGTTGCCCGTTCTGCGGTCATGCCGAAAGCCAGGTCAAGGATAGCCGCCCGTCGGAAGACGGCGCGGCCATCCGGCG
TCGGCGGATGTGTCCTGAGTGCGGCGGACGTTTCACCACGTTCGAGCGCGTTCAGCTTCGCGAACTGATTATCGTGAAGC
GCTCTGGGCGCCGTTCCCCGTTCGATCGCGACAAGCTGGTGCGTTCGGTCGGCCTCGCCACCCAGAAGCGTCCGGTCGAC
CCCGAGCGCGTCGAACGGATGGTCAACGGCATCGTTCGGCAGCTGGAAAGCATGGGCGAAACCGAGCTGCCGTCGTCGAC
GGTGGGCGAGATGGTTATGAAGGCGTTGAAATCGCTCGATGACGTCGCCTATGTCCGATACGCGTCCGTTTACCGTGATT
TCAAGGAAACCAGCGACTTCGCCAAGTTCCTGACCGAAGAGGGTCTGAGCGACGGCGGTGAAGAAGAGCTATAG

Upstream 100 bases:

>100_bases
CCGCCGTCGAGGCCAAGGTTCGCGAAGAAGTGCTGGCCTTGACGGGTCGCTTCCCGATCTACAACTAATAGGGTGATTGC
GCCGCGGAGGGGGCTAGATC

Downstream 100 bases:

>100_bases
TCCGTTAATCCTGATGTGTGTTTGTAGGGGCGCGCGGCGCGCGTGCCCGTGGAGAGTTGAGCTAGATGGTTGAAGACAAA
ATCCGCCTGCTGATCGTGGA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MRCPFCGHAESQVKDSRPSEDGAAIRRRRMCPECGGRFTTFERVQLRELIIVKRSGRRSPFDRDKLVRSVGLATQKRPVD
PERVERMVNGIVRQLESMGETELPSSTVGEMVMKALKSLDDVAYVRYASVYRDFKETSDFAKFLTEEGLSDGGEEEL

Sequences:

>Translated_157_residues
MRCPFCGHAESQVKDSRPSEDGAAIRRRRMCPECGGRFTTFERVQLRELIIVKRSGRRSPFDRDKLVRSVGLATQKRPVD
PERVERMVNGIVRQLESMGETELPSSTVGEMVMKALKSLDDVAYVRYASVYRDFKETSDFAKFLTEEGLSDGGEEEL
>Mature_157_residues
MRCPFCGHAESQVKDSRPSEDGAAIRRRRMCPECGGRFTTFERVQLRELIIVKRSGRRSPFDRDKLVRSVGLATQKRPVD
PERVERMVNGIVRQLESMGETELPSSTVGEMVMKALKSLDDVAYVRYASVYRDFKETSDFAKFLTEEGLSDGGEEEL

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=142, Percent_Identity=45.0704225352113, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_CAUCN (B8H533)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002516793.1
- GeneID:   7330149
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01420
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17855; Mature: 17855

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGHAESQVKDSRPSEDGAAIRRRRMCPECGGRFTTFERVQLRELIIVKRSGRRSP
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
FDRDKLVRSVGLATQKRPVDPERVERMVNGIVRQLESMGETELPSSTVGEMVMKALKSLD
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
DVAYVRYASVYRDFKETSDFAKFLTEEGLSDGGEEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRCPFCGHAESQVKDSRPSEDGAAIRRRRMCPECGGRFTTFERVQLRELIIVKRSGRRSP
CCCCCCCCCHHHHHCCCCCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
FDRDKLVRSVGLATQKRPVDPERVERMVNGIVRQLESMGETELPSSTVGEMVMKALKSLD
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
DVAYVRYASVYRDFKETSDFAKFLTEEGLSDGGEEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA