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The map label for this gene is sucC

Identifier: 16124592

GI number: 16124592

Start: 352434

End: 353633

Strand: Direct

Name: sucC

Synonym: CC_0337

Alternate gene names: 16124592

Gene position: 352434-353633 (Clockwise)

Preceding gene: 16124591

Following gene: 16124593

Centisome position: 8.77

GC content: 64.5

Gene sequence:

>1200_bases
ATGAACATCCACGAACATCAAGCCAAAGCTGTACTCGCCGAGTTCGGCGCCCCCGTGCCGCGCGGCTTCGCCGCCTTCAC
GCCCGATGAAGCCGCCGCCGCCGCCGAAAAGCTGGGTGGGCCGGTCTTCGTCGTGAAGAGCCAGATCCACGCCGGTGGCC
GTGGTAAGGGCAAGTTCGAGGGCCTGGGCCCCGACGCCAAGGGCGGCGTCCGCGTCGTCAAGTCGGTGGAAGAGGTTCGC
TCGAACGCCGAGGAAATGCTGGGCCGCGTCCTTGTGACGCACCAGACCGGCCCGAAGGGCAAGCAGGTCAACCGCCTCTA
CATCGAAGAAGGCGCGGCGATCGCCAAGGAATTCTACCTGTCGCTGCTGGTTGACCGCGCCTCGAGCAAGGTCTCGGTCG
TCGCCTCGACCGAAGGCGGCATGGACATCGAGGACGTCGCCCACTCGACGCCCGAGAAGATCCACACCTTCACCATCGAC
CCGGCGACGGGCGTGTGGCCGACGCATCACCGCGCCCTGGCCAAGGCTCTGGGCCTGACCGGCGGTCTGGCCAAGGAAGC
CGCCTCGCTGCTGAACCAGCTCTATACGGCGTTCATGGCCAAGGACATGGCCATGCTGGAGATCAACCCGCTGATCGTGA
CGGCGGATGATCACCTGCGCGTCCTGGACGCCAAGCTGTCGTTCGACGGCAACAGCCTGTTCCGTCACCCGGACATCAAG
GCGCTGCGCGACGAGAGCGAAGAAGACCCCAAGGAAATCGAAGCGTCGAAGTACGACCTGGCCTACATCGCCCTCGACGG
CGAAATCGGCTGCATGGTCAACGGCGCCGGTCTGGCCATGGCCACCATGGACATCATCAAGCTGTACGGCGCCGAGCCGG
CCAACTTCCTGGATGTCGGCGGCGGCGCCAGCAAGGAGAAGGTCACCGCAGCCTTCAAGATCATCACCGCCGATCCGGCC
GTCAAAGGCATCCTGGTCAACATCTTCGGCGGCATCATGCGCTGCGACATCATCGCCGAAGGCGTGATCGCCGCGGTGAA
GGAAGTCGGTCTCCAGGTTCCGCTGGTCGTCCGTCTGGAAGGCACCAACGTCGAACTCGGCAAGAAAATCATCTCGGAAA
GCGGCCTGAACGTCATCGCCGCCAACGATCTGTCTGACGGCGCCGAGAAGATCGTCGCCGCTGTGAAGGGCGCCCGCTAA

Upstream 100 bases:

>100_bases
GCAAGCCTTCACCTTATCGCCCACACGCGGTTGCGCCTGCGAAACAGCGCTCCTATAACCCGGCCACATTTCAGAAAGCC
GTCGTCGAGACCGGGCCCTC

Downstream 100 bases:

>100_bases
ATGTCGGTTCTGATCGGTTCCCACACCAAGGTCATCTGCCAGGGCATCACCGGCGCTCAAGGCACGTTCCACACCGAGCA
GGCCATCGCGTACGGCACGC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNIHEHQAKAVLAEFGAPVPRGFAAFTPDEAAAAAEKLGGPVFVVKSQIHAGGRGKGKFEGLGPDAKGGVRVVKSVEEVR
SNAEEMLGRVLVTHQTGPKGKQVNRLYIEEGAAIAKEFYLSLLVDRASSKVSVVASTEGGMDIEDVAHSTPEKIHTFTID
PATGVWPTHHRALAKALGLTGGLAKEAASLLNQLYTAFMAKDMAMLEINPLIVTADDHLRVLDAKLSFDGNSLFRHPDIK
ALRDESEEDPKEIEASKYDLAYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPA
VKGILVNIFGGIMRCDIIAEGVIAAVKEVGLQVPLVVRLEGTNVELGKKIISESGLNVIAANDLSDGAEKIVAAVKGAR

Sequences:

>Translated_399_residues
MNIHEHQAKAVLAEFGAPVPRGFAAFTPDEAAAAAEKLGGPVFVVKSQIHAGGRGKGKFEGLGPDAKGGVRVVKSVEEVR
SNAEEMLGRVLVTHQTGPKGKQVNRLYIEEGAAIAKEFYLSLLVDRASSKVSVVASTEGGMDIEDVAHSTPEKIHTFTID
PATGVWPTHHRALAKALGLTGGLAKEAASLLNQLYTAFMAKDMAMLEINPLIVTADDHLRVLDAKLSFDGNSLFRHPDIK
ALRDESEEDPKEIEASKYDLAYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPA
VKGILVNIFGGIMRCDIIAEGVIAAVKEVGLQVPLVVRLEGTNVELGKKIISESGLNVIAANDLSDGAEKIVAAVKGAR
>Mature_399_residues
MNIHEHQAKAVLAEFGAPVPRGFAAFTPDEAAAAAEKLGGPVFVVKSQIHAGGRGKGKFEGLGPDAKGGVRVVKSVEEVR
SNAEEMLGRVLVTHQTGPKGKQVNRLYIEEGAAIAKEFYLSLLVDRASSKVSVVASTEGGMDIEDVAHSTPEKIHTFTID
PATGVWPTHHRALAKALGLTGGLAKEAASLLNQLYTAFMAKDMAMLEINPLIVTADDHLRVLDAKLSFDGNSLFRHPDIK
ALRDESEEDPKEIEASKYDLAYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPA
VKGILVNIFGGIMRCDIIAEGVIAAVKEVGLQVPLVVRLEGTNVELGKKIISESGLNVIAANDLSDGAEKIVAAVKGAR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.0559796437659, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=47.5452196382429, Blast_Score=344, Evalue=9e-95,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=47.5409836065574, Blast_Score=324, Evalue=8e-89,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=55.4156171284635, Blast_Score=433, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=46.3291139240506, Blast_Score=346, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=43.6224489795918, Blast_Score=327, Evalue=8e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=45.0632911392405, Blast_Score=352, Evalue=6e-98,
Organism=Drosophila melanogaster, GI161078106, Length=390, Percent_Identity=49.4871794871795, Blast_Score=359, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24645208, Length=390, Percent_Identity=49.4871794871795, Blast_Score=359, Evalue=2e-99,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=49.238578680203, Blast_Score=355, Evalue=2e-98,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=49.238578680203, Blast_Score=355, Evalue=2e-98,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=47.8589420654912, Blast_Score=345, Evalue=2e-95,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_CAUCN (B8GYZ1)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002515715.1
- ProteinModelPortal:   B8GYZ1
- SMR:   B8GYZ1
- GeneID:   7331039
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_00340
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42038; Mature: 42038

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEHQAKAVLAEFGAPVPRGFAAFTPDEAAAAAEKLGGPVFVVKSQIHAGGRGKGKFE
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCC
GLGPDAKGGVRVVKSVEEVRSNAEEMLGRVLVTHQTGPKGKQVNRLYIEEGAAIAKEFYL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEECCCHHHHHHHHH
SLLVDRASSKVSVVASTEGGMDIEDVAHSTPEKIHTFTIDPATGVWPTHHRALAKALGLT
HHHHHCCCCCEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCC
GGLAKEAASLLNQLYTAFMAKDMAMLEINPLIVTADDHLRVLDAKLSFDGNSLFRHPDIK
CCHHHHHHHHHHHHHHHHHHCCEEEEEECEEEEECCCCEEEEEEEEECCCCCCCCCCCHH
ALRDESEEDPKEIEASKYDLAYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHCCCCCCHHHHCCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPAVKGILVNIFGGIMRCDIIAEGVIAAVKEVGLQVPLVVRLE
CCCCCHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKIISESGLNVIAANDLSDGAEKIVAAVKGAR
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIHEHQAKAVLAEFGAPVPRGFAAFTPDEAAAAAEKLGGPVFVVKSQIHAGGRGKGKFE
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCC
GLGPDAKGGVRVVKSVEEVRSNAEEMLGRVLVTHQTGPKGKQVNRLYIEEGAAIAKEFYL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEECCCHHHHHHHHH
SLLVDRASSKVSVVASTEGGMDIEDVAHSTPEKIHTFTIDPATGVWPTHHRALAKALGLT
HHHHHCCCCCEEEEEECCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCC
GGLAKEAASLLNQLYTAFMAKDMAMLEINPLIVTADDHLRVLDAKLSFDGNSLFRHPDIK
CCHHHHHHHHHHHHHHHHHHCCEEEEEECEEEEECCCCEEEEEEEEECCCCCCCCCCCHH
ALRDESEEDPKEIEASKYDLAYIALDGEIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHCCCCCCHHHHCCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPAVKGILVNIFGGIMRCDIIAEGVIAAVKEVGLQVPLVVRLE
CCCCCHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKIISESGLNVIAANDLSDGAEKIVAAVKGAR
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA