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The map label for this gene is appC [H]

Identifier: 13488279

GI number: 13488279

Start: 250317

End: 251150

Strand: Direct

Name: appC [H]

Synonym: mlr9273

Alternate gene names: 13488279

Gene position: 250317-251150 (Clockwise)

Preceding gene: 13488278

Following gene: 13488280

Centisome position: 71.13

GC content: 62.95

Gene sequence:

>834_bases
ATGCAGAAGAAGTCACGGATTGACCTGCCGACGCTCTTTGCGTCGCTCTGGCTTTGCCTGATGCTGCTGATCGCGGCGGC
CGCGCCGCTGATCGCTCCGCATGACATCACCGCGATGGATTTGCGTCATCGCCTGGCGCCGCCCTTCGGCTTCGGCGGCG
CGGCCGTCCACCTGTTCGGCTCCGACGATCTTGGCCGCGATGTCGCCTCGCGTCTTTATTACTCGATCCGCACCAGCCTG
CTCATCGCCTTTGGCGCAACCGTTATCAGCGTCCTCGTCGGAACCGCGATCGGCTTTCTTGCCGCCTATTTCCGGGGCCT
CATCGAGCATTTCCTGTTGCTGCTCATCGACGTCCAGGCGTCGCTGCCTTTCCTGATCGTCGCGCTGGCGATGCTGGCGT
TCTTCGGCAACTCGCTGCCGCTGGTCGTCGGCTTGATGGGCCTTTATGGATGGGAGCGCAACGCGCGGCTCGCGCGTGGT
CTCGCACTTGCAGCCGGCGCGCAAGGATATGCGGGCGCGACCCGTCAGCTCGGCGCTCATCCCTTGCGCATCTATCTCCG
TCACATCCTTCCCAACAGCGCGGCAACGCTTCTTGTTGCGGCAACGGTCACGTTTCCGGAGATCATTCTGGTCGAAAGCG
GCCTGTCCTTCCTCGGGCTCGGCGTCCAGCCACCTATGACCAGCCTCGGCGTCATGGTCGGCACTGGCCGCGAATACATT
ACGCGCGCGCCCTGGATGTTGCTTAGCCCCAGCATCGTCATCGTGCTGACGGCCGTCGCCGTCAGCGTTTTGGGCGATTT
CTTGCGCGACAAACTCGATCCCACTCTCAAGTAA

Upstream 100 bases:

>100_bases
ACTCACCATGACGTCGGCGAACCTGATGATGGATCTGCTCTACGGCGTCGTCGATCCCCGCTTGCGACAAGCGCGCCCGG
GATCACACTGAGGAAGCCAG

Downstream 100 bases:

>100_bases
CGGATATCTCCCATGCGGAAAAAACTGATTTCCATCCTTGTTGACGGCGTCAGCGCTGACACTTTCGAAAAGCATGCTCA
TCGCCTGCCCAACATGCGCC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MQKKSRIDLPTLFASLWLCLMLLIAAAAPLIAPHDITAMDLRHRLAPPFGFGGAAVHLFGSDDLGRDVASRLYYSIRTSL
LIAFGATVISVLVGTAIGFLAAYFRGLIEHFLLLLIDVQASLPFLIVALAMLAFFGNSLPLVVGLMGLYGWERNARLARG
LALAAGAQGYAGATRQLGAHPLRIYLRHILPNSAATLLVAATVTFPEIILVESGLSFLGLGVQPPMTSLGVMVGTGREYI
TRAPWMLLSPSIVIVLTAVAVSVLGDFLRDKLDPTLK

Sequences:

>Translated_277_residues
MQKKSRIDLPTLFASLWLCLMLLIAAAAPLIAPHDITAMDLRHRLAPPFGFGGAAVHLFGSDDLGRDVASRLYYSIRTSL
LIAFGATVISVLVGTAIGFLAAYFRGLIEHFLLLLIDVQASLPFLIVALAMLAFFGNSLPLVVGLMGLYGWERNARLARG
LALAAGAQGYAGATRQLGAHPLRIYLRHILPNSAATLLVAATVTFPEIILVESGLSFLGLGVQPPMTSLGVMVGTGREYI
TRAPWMLLSPSIVIVLTAVAVSVLGDFLRDKLDPTLK
>Mature_277_residues
MQKKSRIDLPTLFASLWLCLMLLIAAAAPLIAPHDITAMDLRHRLAPPFGFGGAAVHLFGSDDLGRDVASRLYYSIRTSL
LIAFGATVISVLVGTAIGFLAAYFRGLIEHFLLLLIDVQASLPFLIVALAMLAFFGNSLPLVVGLMGLYGWERNARLARG
LALAAGAQGYAGATRQLGAHPLRIYLRHILPNSAATLLVAATVTFPEIILVESGLSFLGLGVQPPMTSLGVMVGTGREYI
TRAPWMLLSPSIVIVLTAVAVSVLGDFLRDKLDPTLK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=275, Percent_Identity=32.7272727272727, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=33.9622641509434, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789964, Length=257, Percent_Identity=37.3540856031128, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787498, Length=258, Percent_Identity=32.9457364341085, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=32.3770491803279, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787549, Length=239, Percent_Identity=31.7991631799163, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788505, Length=251, Percent_Identity=26.6932270916335, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29588; Mature: 29588

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKSRIDLPTLFASLWLCLMLLIAAAAPLIAPHDITAMDLRHRLAPPFGFGGAAVHLFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEC
SDDLGRDVASRLYYSIRTSLLIAFGATVISVLVGTAIGFLAAYFRGLIEHFLLLLIDVQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPFLIVALAMLAFFGNSLPLVVGLMGLYGWERNARLARGLALAAGAQGYAGATRQLGAH
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCH
PLRIYLRHILPNSAATLLVAATVTFPEIILVESGLSFLGLGVQPPMTSLGVMVGTGREYI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHEEECCHHHH
TRAPWMLLSPSIVIVLTAVAVSVLGDFLRDKLDPTLK
HHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQKKSRIDLPTLFASLWLCLMLLIAAAAPLIAPHDITAMDLRHRLAPPFGFGGAAVHLFG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEC
SDDLGRDVASRLYYSIRTSLLIAFGATVISVLVGTAIGFLAAYFRGLIEHFLLLLIDVQA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPFLIVALAMLAFFGNSLPLVVGLMGLYGWERNARLARGLALAAGAQGYAGATRQLGAH
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHCCH
PLRIYLRHILPNSAATLLVAATVTFPEIILVESGLSFLGLGVQPPMTSLGVMVGTGREYI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHEEECCHHHH
TRAPWMLLSPSIVIVLTAVAVSVLGDFLRDKLDPTLK
HHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]