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The map label for this gene is gsiC [H]

Identifier: 13488278

GI number: 13488278

Start: 249366

End: 250307

Strand: Direct

Name: gsiC [H]

Synonym: mlr9272

Alternate gene names: 13488278

Gene position: 249366-250307 (Clockwise)

Preceding gene: 13488277

Following gene: 13488279

Centisome position: 70.86

GC content: 62.95

Gene sequence:

>942_bases
ATGACCGGCTTGCTCCCTTACATCGGCCCCAAACTTCTGCGGGCCGCGCTCTCGATCATCGTCGTCGTGACGATCACATT
CTTCGTGCTACGCGCTTCAGGAGATCCGGCCCTGCAGATTCTCGGGCCCGGCGCTCGCGCCCCCGACCTCGAAGCGTTTC
GCCAGCGGTGGGGATTGGATCAGCCCCTGCACGTTCAATATCTTCGCTATCTCTGGGGCGCGTTGCACGGCGATTTCGGC
AACTCGATGCTGGCCGGCAAGCCCGCCGCGGAGCTTGTGCTTGGGCGAATGCCTTTGACGTTGGCCCTGATGCTGCCGGC
ACTCGCGCTCAACGTGCTGATCGGCATCCCGGTCGGCGCCTATGCGGCCATGCATCGAGACAGCTGGATCGACCGGTCGG
TGATGATGCTGACCGTGCTCGGCTTTACCGTGCCAAGCTTCGTGCTCGGCTTGCTGTTCATCCTGATATTTTCGGTGACG
CTCGGCCTGTTTCCCTCAGGCGGGGCCGACAAATGGCAAAGCTTTGTTCTGCCGGTGCTGACGCTTGGCATAGGCGGGGC
GGCAATGCTCGCGCGGTTTACGCGTAGCGCCATGATCGAGGTTCTGTCGCAGCTCTACGTCGTTGCCGCCAGCGCCAAGG
GCGTCACCTGGCGCCAGGTCATTCACCACCACGCCTTCCCCAACGCCATCATCCCGATTCTCACATTGCTGGGTCTGATG
CTGGGCGGACAGGTGGCCGGGGCGGTGCTGGTCGAAAACGTCTTCGGCTGGCCGGGCATTGGTCAACTGCTCGTGGTCTC
CGTCGGCAATCGAGATCTCGCGGTCGTGCAGGTCATCCTCCTGCTCGTGGCACTCACCATGACGTCGGCGAACCTGATGA
TGGATCTGCTCTACGGCGTCGTCGATCCCCGCTTGCGACAAGCGCGCCCGGGATCACACTGA

Upstream 100 bases:

>100_bases
CGCGCTGTCGTCTGGCAAAAGATATCTGCCGGCAGACGCAACCTGAACTCCTTCCACACGGACCAGAACGGCGGGTCGCC
TGCCATCTGGTATCAATTCC

Downstream 100 bases:

>100_bases
GGAAGCCAGATGCAGAAGAAGTCACGGATTGACCTGCCGACGCTCTTTGCGTCGCTCTGGCTTTGCCTGATGCTGCTGAT
CGCGGCGGCCGCGCCGCTGA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTGLLPYIGPKLLRAALSIIVVVTITFFVLRASGDPALQILGPGARAPDLEAFRQRWGLDQPLHVQYLRYLWGALHGDFG
NSMLAGKPAAELVLGRMPLTLALMLPALALNVLIGIPVGAYAAMHRDSWIDRSVMMLTVLGFTVPSFVLGLLFILIFSVT
LGLFPSGGADKWQSFVLPVLTLGIGGAAMLARFTRSAMIEVLSQLYVVAASAKGVTWRQVIHHHAFPNAIIPILTLLGLM
LGGQVAGAVLVENVFGWPGIGQLLVVSVGNRDLAVVQVILLLVALTMTSANLMMDLLYGVVDPRLRQARPGSH

Sequences:

>Translated_313_residues
MTGLLPYIGPKLLRAALSIIVVVTITFFVLRASGDPALQILGPGARAPDLEAFRQRWGLDQPLHVQYLRYLWGALHGDFG
NSMLAGKPAAELVLGRMPLTLALMLPALALNVLIGIPVGAYAAMHRDSWIDRSVMMLTVLGFTVPSFVLGLLFILIFSVT
LGLFPSGGADKWQSFVLPVLTLGIGGAAMLARFTRSAMIEVLSQLYVVAASAKGVTWRQVIHHHAFPNAIIPILTLLGLM
LGGQVAGAVLVENVFGWPGIGQLLVVSVGNRDLAVVQVILLLVALTMTSANLMMDLLYGVVDPRLRQARPGSH
>Mature_312_residues
TGLLPYIGPKLLRAALSIIVVVTITFFVLRASGDPALQILGPGARAPDLEAFRQRWGLDQPLHVQYLRYLWGALHGDFGN
SMLAGKPAAELVLGRMPLTLALMLPALALNVLIGIPVGAYAAMHRDSWIDRSVMMLTVLGFTVPSFVLGLLFILIFSVTL
GLFPSGGADKWQSFVLPVLTLGIGGAAMLARFTRSAMIEVLSQLYVVAASAKGVTWRQVIHHHAFPNAIIPILTLLGLML
GGQVAGAVLVENVFGWPGIGQLLVVSVGNRDLAVVQVILLLVALTMTSANLMMDLLYGVVDPRLRQARPGSH

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=304, Percent_Identity=42.7631578947368, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1789888, Length=314, Percent_Identity=35.9872611464968, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1789965, Length=325, Percent_Identity=36.3076923076923, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=33.7662337662338, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1787761, Length=314, Percent_Identity=37.8980891719745, Blast_Score=161, Evalue=5e-41,
Organism=Escherichia coli, GI1787550, Length=262, Percent_Identity=30.1526717557252, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788504, Length=287, Percent_Identity=27.8745644599303, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33539; Mature: 33408

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLLPYIGPKLLRAALSIIVVVTITFFVLRASGDPALQILGPGARAPDLEAFRQRWGLD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCC
QPLHVQYLRYLWGALHGDFGNSMLAGKPAAELVLGRMPLTLALMLPALALNVLIGIPVGA
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHH
YAAMHRDSWIDRSVMMLTVLGFTVPSFVLGLLFILIFSVTLGLFPSGGADKWQSFVLPVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TLGIGGAAMLARFTRSAMIEVLSQLYVVAASAKGVTWRQVIHHHAFPNAIIPILTLLGLM
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
LGGQVAGAVLVENVFGWPGIGQLLVVSVGNRDLAVVQVILLLVALTMTSANLMMDLLYGV
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDPRLRQARPGSH
HCHHHHCCCCCCC
>Mature Secondary Structure 
TGLLPYIGPKLLRAALSIIVVVTITFFVLRASGDPALQILGPGARAPDLEAFRQRWGLD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHCCCC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HCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA