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The map label for this gene is dhaK [H]

Identifier: 13488187

GI number: 13488187

Start: 19049

End: 20047

Strand: Direct

Name: dhaK [H]

Synonym: mlr9018

Alternate gene names: 13488187

Gene position: 19049-20047 (Clockwise)

Preceding gene: 13488186

Following gene: 13488188

Centisome position: 5.41

GC content: 57.76

Gene sequence:

>999_bases
ATGAAGAAGCTGATCAACAGTCCTGAGAAATATGTGGATGAAGCGCTGGCGGGGATGAGTTTGGCGCACCAGGGTGCCTA
CAAGATTTCCGGCAGCAACGGCCGTGTCATTGAACGGGCCAAGAAAAAGGCTTGGGGCAAGGTTGGAGTTGTTTCCGGCG
GTGGCTTTGGGCACTTGCCGCTGTTTGCCGGATATGTCGGAGAAGGACTGCTGGATGCCTGCGCAGTCGGGCATGTGTTC
GCCGGCCCGTCCTACGACGACATATCCGAGGCCTTGAACGCGGCTGACCACGGCGGTGGCGTTCTATCGGTCATTGCCAA
TTATGGCGGCGACACCATGGTGTTTGGCATGGTCAATGACACGTTGATCGCTGAGGGCAAGGACTGCGCCACCGTAATTG
TGGCCGATGACGTTGCAAGTGCAGACAAGGATCGAGCCGACACGCGTCGCGGCGTGGCTGGGATCATCTTCGCATTCAAA
GTTGCTGGAGCCGCAGCGGAAAGGGGACTCAGCCTACATGAGGTGAAAGCTGTGACTGAAAAGGCCATGGCTGGTTGCCG
GTCCATAGGGGTTGCACTATCGGCCTGCACAGTACCCCAGGCGGGCGAGCCGACCTTTCATCTCGAAGAAGATGCCATTG
AAATGGGCATGGGCATTCACGGTGAGAAAGGATTGTGGCGCGGGTCGCTTAAACCCGCTGACGAAATTGCCGCAGAGATG
GTCGAACGCTTGTTGGCTGACCTCAAACCCGCACAGGGGTCTAGCGTGGCGGTTCTGGTCAACGGCCTGGGTGCAACACC
GCTGGAAGAACTCTACATTCTGTACCGCAAAGTGGCCCACCTGATCGAGGCAGCGGGTCTGAAGATCGCCTACTCACTTG
CTGGTGAATACGCGACTTCAATGGAAATGGCGGGCGCCTCGGTGAGCGTTATGCAGGTCGACGATGAATTGCTCGGTCTG
TTGAATGCCCCTGCCCAATGTCCCCTGTGGAGAGCGTGA

Upstream 100 bases:

>100_bases
TACCGGGCCCAACCGGATTGCGAGGGCTTTTGAAAACACTGCAGGTGGCTTGTGGCCCCGCCGGACAAGTACTGAAGCGA
TAGACTGGCAGAGCGAGAAC

Downstream 100 bases:

>100_bases
TGGAGACCGTCTTCACCGGAACAGATGTAGGCGCAGCCATGCGTCGCGTCGCGCTGGCGCTCGTCGAGAGCAAAGATCGA
TTTAACAAGCTTGATGCTGC

Product: putative glycerone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKLINSPEKYVDEALAGMSLAHQGAYKISGSNGRVIERAKKKAWGKVGVVSGGGFGHLPLFAGYVGEGLLDACAVGHVF
AGPSYDDISEALNAADHGGGVLSVIANYGGDTMVFGMVNDTLIAEGKDCATVIVADDVASADKDRADTRRGVAGIIFAFK
VAGAAAERGLSLHEVKAVTEKAMAGCRSIGVALSACTVPQAGEPTFHLEEDAIEMGMGIHGEKGLWRGSLKPADEIAAEM
VERLLADLKPAQGSSVAVLVNGLGATPLEELYILYRKVAHLIEAAGLKIAYSLAGEYATSMEMAGASVSVMQVDDELLGL
LNAPAQCPLWRA

Sequences:

>Translated_332_residues
MKKLINSPEKYVDEALAGMSLAHQGAYKISGSNGRVIERAKKKAWGKVGVVSGGGFGHLPLFAGYVGEGLLDACAVGHVF
AGPSYDDISEALNAADHGGGVLSVIANYGGDTMVFGMVNDTLIAEGKDCATVIVADDVASADKDRADTRRGVAGIIFAFK
VAGAAAERGLSLHEVKAVTEKAMAGCRSIGVALSACTVPQAGEPTFHLEEDAIEMGMGIHGEKGLWRGSLKPADEIAAEM
VERLLADLKPAQGSSVAVLVNGLGATPLEELYILYRKVAHLIEAAGLKIAYSLAGEYATSMEMAGASVSVMQVDDELLGL
LNAPAQCPLWRA
>Mature_332_residues
MKKLINSPEKYVDEALAGMSLAHQGAYKISGSNGRVIERAKKKAWGKVGVVSGGGFGHLPLFAGYVGEGLLDACAVGHVF
AGPSYDDISEALNAADHGGGVLSVIANYGGDTMVFGMVNDTLIAEGKDCATVIVADDVASADKDRADTRRGVAGIIFAFK
VAGAAAERGLSLHEVKAVTEKAMAGCRSIGVALSACTVPQAGEPTFHLEEDAIEMGMGIHGEKGLWRGSLKPADEIAAEM
VERLLADLKPAQGSSVAVLVNGLGATPLEELYILYRKVAHLIEAAGLKIAYSLAGEYATSMEMAGASVSVMQVDDELLGL
LNAPAQCPLWRA

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=340, Percent_Identity=37.6470588235294, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI87081857, Length=352, Percent_Identity=39.4886363636364, Blast_Score=234, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17565018, Length=329, Percent_Identity=34.9544072948328, Blast_Score=194, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6321055, Length=297, Percent_Identity=33.3333333333333, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6323570, Length=347, Percent_Identity=29.971181556196, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 34444; Mature: 34444

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLINSPEKYVDEALAGMSLAHQGAYKISGSNGRVIERAKKKAWGKVGVVSGGGFGHLP
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCHH
LFAGYVGEGLLDACAVGHVFAGPSYDDISEALNAADHGGGVLSVIANYGGDTMVFGMVND
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECC
TLIAEGKDCATVIVADDVASADKDRADTRRGVAGIIFAFKVAGAAAERGLSLHEVKAVTE
EEEECCCCCEEEEEECCHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KAMAGCRSIGVALSACTVPQAGEPTFHLEEDAIEMGMGIHGEKGLWRGSLKPADEIAAEM
HHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
VERLLADLKPAQGSSVAVLVNGLGATPLEELYILYRKVAHLIEAAGLKIAYSLAGEYATS
HHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
MEMAGASVSVMQVDDELLGLLNAPAQCPLWRA
HHHCCCEEEEEECCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKLINSPEKYVDEALAGMSLAHQGAYKISGSNGRVIERAKKKAWGKVGVVSGGGFGHLP
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCEEEECCCCCCCHH
LFAGYVGEGLLDACAVGHVFAGPSYDDISEALNAADHGGGVLSVIANYGGDTMVFGMVND
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECC
TLIAEGKDCATVIVADDVASADKDRADTRRGVAGIIFAFKVAGAAAERGLSLHEVKAVTE
EEEECCCCCEEEEEECCHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KAMAGCRSIGVALSACTVPQAGEPTFHLEEDAIEMGMGIHGEKGLWRGSLKPADEIAAEM
HHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
VERLLADLKPAQGSSVAVLVNGLGATPLEELYILYRKVAHLIEAAGLKIAYSLAGEYATS
HHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
MEMAGASVSVMQVDDELLGLLNAPAQCPLWRA
HHHCCCEEEEEECCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]