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The map label for this gene is aglA [H]

Identifier: 13476308

GI number: 13476308

Start: 6282133

End: 6283767

Strand: Direct

Name: aglA [H]

Synonym: mlr7593

Alternate gene names: 13476308

Gene position: 6282133-6283767 (Clockwise)

Preceding gene: 13476307

Following gene: 13476311

Centisome position: 89.28

GC content: 64.77

Gene sequence:

>1635_bases
GTGATGGCCGACGACAATGCGGGGCAGGGGGCCGACTGGTGGCGCGGCTGCGTCATCTACCAAGTCTATCCGCGTTCCTT
CCAGGACACGACCGGCGACGGCAGCGGCGATCTTAGGGGTATCACCACGCGGCTTGGCCACATCGCTTCGCTCGGCGTCG
ATGCCGTCTGGCTGTCGCCCTTCTTCAAGTCGCCAATGGCCGACATGGGCTATGACGTTTCGGATTATCGCGACGTCGAT
CCGATGTTCGGTTCACTTGAGGATTTCGACGCTCTGGTCACCGAGGCGCACCGGTTGGGCCTGAAGGTCGTCATCGACCA
GGTCTTGTCGCACTCATCCGACAAGCACGAATGGTTCGTCCAAAGCCGCGCCAGCCGCGACAATCCCAAGGCTGACTGGT
ACGTCTGGGCCGATACGAAACCCGACGGCAACGCGCCCAACAACTGGCTGTCCGTCTTCGGCGGCCCGGCCTGGGAGTGG
GATTCGACCCGCCGGCAATATTACATGCACAATTTCCTCGCCTCGCAGCCCGATCTGAATTTCCACAATCCAGAGGTCCA
GGATGCGCTGCTGGACACGGTGCGCTTCTGGCTGGAGCGTGGCGTCGACGGTTTTCGGCTCGATACGGTCAACTACTATG
TCCACGACCGCTGGCTGCGCAGCAATCCGCCGCTGGCGTCGAGCGTCGCCGGCACCAATGGCGAGACCAACACCTACCTC
TACCAGGAGCATCTGTTCGACAAGACGCAGCCGGAAAACCTGGCTTTCCTCAGGCGTTTCCGGGGGTTGCTAGACGAATA
TCCCGACCGCGCCGCCGTCGGCGAAATCGGCGATGAGGGCCGCTCGCTGCAGACGCTGGCTGCCTACACCTCCGGCGGCG
ACAAGCTGCAGATGTGCTACACCTTCGACCTGCTCGGCCCGCAGTTTTCGGCGGCGCATGTGCGCGGCTGCGTCGAGGCC
TTCGAACAAGCGGTTACCGACGGCTGGGTCTGCTGGGCGTTTTCCAACCATGACGTGGTGCGCCATGTCAGCCGCTGGAC
TGGGCCGGACGGCGATGCCGATGCGGTAGCCAGATTCTCGATCATGCTGCTCGCCTGCCTGCGCGGCTCGATATGCCTCT
ATCAGGGCGAGGAGCTCGGCCTGGAGGAGGCGGAGCTTGCCTATGAGGATCTGCGCGATCCCGTCGGCATCCGCTTCTGG
CCCGGCATGAAGGGCAGGGATGGCTGCCGCACGCCGATGGTCTGGGAAGCCGGCGCCGACAATGCGGGTTTCTCGACGGC
CAGGCCCTGGCTGCCGGTCCCGGCCAGCCATCGCGCCCGCGCCACCGACGTGCAGAACGGCAGCGAGCAATCGGTGCTGT
CCGCCTACCGCTCGACGCTTGCCTTGCGCAGGCGGCATCCGGCGCTGGTCAGCGGCTCGATCCGCTTTCTCGACGCCGAA
GGCGATGTGCTGGCCTTCATCCGCGAAGGCGACGGGCAGAGGCTGCTCTGCGTCTTCAATTTCGCCGGGGAGCCGGGGAA
TTGGCCCTTGCCACCGGATATTGGCGTCGCTGCTGTCCTGGCTGGCGCCGCTGTTGTCGAGGAAGAAGCGCTCTCGCTGC
CGGCTCTCGGTTGCTTCCTTGGCCGGCTCGACTGA

Upstream 100 bases:

>100_bases
AGAGCATCGGACCGAAAAGTGGCAGTCGGTTTTCGGGCAATCCGATGCGAGCAAAAAATAGTTCGCGCCAGGCCGCAAAG
GGCTGCGCCAGGAGGGGTTC

Downstream 100 bases:

>100_bases
CTGGCGGCTCGACCGCGCCTTGGCCGGGCGATCCGCTTGGCCACCAAGCCTTACTGAACGAGCACCGCCCGTCCGCAGGT
CGCTCCGGTGACGCGCACAT

Product: glycosyl hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MMADDNAGQGADWWRGCVIYQVYPRSFQDTTGDGSGDLRGITTRLGHIASLGVDAVWLSPFFKSPMADMGYDVSDYRDVD
PMFGSLEDFDALVTEAHRLGLKVVIDQVLSHSSDKHEWFVQSRASRDNPKADWYVWADTKPDGNAPNNWLSVFGGPAWEW
DSTRRQYYMHNFLASQPDLNFHNPEVQDALLDTVRFWLERGVDGFRLDTVNYYVHDRWLRSNPPLASSVAGTNGETNTYL
YQEHLFDKTQPENLAFLRRFRGLLDEYPDRAAVGEIGDEGRSLQTLAAYTSGGDKLQMCYTFDLLGPQFSAAHVRGCVEA
FEQAVTDGWVCWAFSNHDVVRHVSRWTGPDGDADAVARFSIMLLACLRGSICLYQGEELGLEEAELAYEDLRDPVGIRFW
PGMKGRDGCRTPMVWEAGADNAGFSTARPWLPVPASHRARATDVQNGSEQSVLSAYRSTLALRRRHPALVSGSIRFLDAE
GDVLAFIREGDGQRLLCVFNFAGEPGNWPLPPDIGVAAVLAGAAVVEEEALSLPALGCFLGRLD

Sequences:

>Translated_544_residues
MMADDNAGQGADWWRGCVIYQVYPRSFQDTTGDGSGDLRGITTRLGHIASLGVDAVWLSPFFKSPMADMGYDVSDYRDVD
PMFGSLEDFDALVTEAHRLGLKVVIDQVLSHSSDKHEWFVQSRASRDNPKADWYVWADTKPDGNAPNNWLSVFGGPAWEW
DSTRRQYYMHNFLASQPDLNFHNPEVQDALLDTVRFWLERGVDGFRLDTVNYYVHDRWLRSNPPLASSVAGTNGETNTYL
YQEHLFDKTQPENLAFLRRFRGLLDEYPDRAAVGEIGDEGRSLQTLAAYTSGGDKLQMCYTFDLLGPQFSAAHVRGCVEA
FEQAVTDGWVCWAFSNHDVVRHVSRWTGPDGDADAVARFSIMLLACLRGSICLYQGEELGLEEAELAYEDLRDPVGIRFW
PGMKGRDGCRTPMVWEAGADNAGFSTARPWLPVPASHRARATDVQNGSEQSVLSAYRSTLALRRRHPALVSGSIRFLDAE
GDVLAFIREGDGQRLLCVFNFAGEPGNWPLPPDIGVAAVLAGAAVVEEEALSLPALGCFLGRLD
>Mature_544_residues
MMADDNAGQGADWWRGCVIYQVYPRSFQDTTGDGSGDLRGITTRLGHIASLGVDAVWLSPFFKSPMADMGYDVSDYRDVD
PMFGSLEDFDALVTEAHRLGLKVVIDQVLSHSSDKHEWFVQSRASRDNPKADWYVWADTKPDGNAPNNWLSVFGGPAWEW
DSTRRQYYMHNFLASQPDLNFHNPEVQDALLDTVRFWLERGVDGFRLDTVNYYVHDRWLRSNPPLASSVAGTNGETNTYL
YQEHLFDKTQPENLAFLRRFRGLLDEYPDRAAVGEIGDEGRSLQTLAAYTSGGDKLQMCYTFDLLGPQFSAAHVRGCVEA
FEQAVTDGWVCWAFSNHDVVRHVSRWTGPDGDADAVARFSIMLLACLRGSICLYQGEELGLEEAELAYEDLRDPVGIRFW
PGMKGRDGCRTPMVWEAGADNAGFSTARPWLPVPASHRARATDVQNGSEQSVLSAYRSTLALRRRHPALVSGSIRFLDAE
GDVLAFIREGDGQRLLCVFNFAGEPGNWPLPPDIGVAAVLAGAAVVEEEALSLPALGCFLGRLD

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=512, Percent_Identity=33.203125, Blast_Score=269, Evalue=5e-72,
Organism=Escherichia coli, GI1790687, Length=536, Percent_Identity=34.3283582089552, Blast_Score=288, Evalue=8e-79,
Organism=Escherichia coli, GI1786604, Length=532, Percent_Identity=24.812030075188, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32565753, Length=519, Percent_Identity=25.626204238921, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25147709, Length=550, Percent_Identity=24.5454545454545, Blast_Score=113, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321731, Length=574, Percent_Identity=30.8362369337979, Blast_Score=278, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6319776, Length=574, Percent_Identity=30.8362369337979, Blast_Score=277, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6322245, Length=560, Percent_Identity=31.0714285714286, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6321726, Length=581, Percent_Identity=31.3253012048193, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6324416, Length=589, Percent_Identity=31.5789473684211, Blast_Score=261, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6322241, Length=595, Percent_Identity=31.2605042016807, Blast_Score=260, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6322021, Length=595, Percent_Identity=31.2605042016807, Blast_Score=260, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24583745, Length=513, Percent_Identity=38.7914230019493, Blast_Score=320, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24583749, Length=479, Percent_Identity=39.0396659707724, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24583747, Length=479, Percent_Identity=39.0396659707724, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24586587, Length=497, Percent_Identity=37.0221327967807, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24586599, Length=524, Percent_Identity=34.3511450381679, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24586591, Length=546, Percent_Identity=34.981684981685, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24586597, Length=514, Percent_Identity=34.2412451361868, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24586589, Length=506, Percent_Identity=36.7588932806324, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI45549022, Length=522, Percent_Identity=32.7586206896552, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24586593, Length=544, Percent_Identity=34.375, Blast_Score=281, Evalue=8e-76,
Organism=Drosophila melanogaster, GI221330053, Length=512, Percent_Identity=34.375, Blast_Score=277, Evalue=2e-74,
Organism=Drosophila melanogaster, GI281360393, Length=485, Percent_Identity=31.9587628865979, Blast_Score=212, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 60498; Mature: 60498

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMADDNAGQGADWWRGCVIYQVYPRSFQDTTGDGSGDLRGITTRLGHIASLGVDAVWLSP
CCCCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCH
FFKSPMADMGYDVSDYRDVDPMFGSLEDFDALVTEAHRLGLKVVIDQVLSHSSDKHEWFV
HHCCCHHHCCCCCHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QSRASRDNPKADWYVWADTKPDGNAPNNWLSVFGGPAWEWDSTRRQYYMHNFLASQPDLN
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCC
FHNPEVQDALLDTVRFWLERGVDGFRLDTVNYYVHDRWLRSNPPLASSVAGTNGETNTYL
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCCCCCCEEE
YQEHLFDKTQPENLAFLRRFRGLLDEYPDRAAVGEIGDEGRSLQTLAAYTSGGDKLQMCY
EHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEHHHCCCCCCEEEEEE
TFDLLGPQFSAAHVRGCVEAFEQAVTDGWVCWAFSNHDVVRHVSRWTGPDGDADAVARFS
EEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
IMLLACLRGSICLYQGEELGLEEAELAYEDLRDPVGIRFWPGMKGRDGCRTPMVWEAGAD
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEECCCC
NAGFSTARPWLPVPASHRARATDVQNGSEQSVLSAYRSTLALRRRHPALVSGSIRFLDAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCEEEEECC
GDVLAFIREGDGQRLLCVFNFAGEPGNWPLPPDIGVAAVLAGAAVVEEEALSLPALGCFL
CCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
GRLD
HCCC
>Mature Secondary Structure
MMADDNAGQGADWWRGCVIYQVYPRSFQDTTGDGSGDLRGITTRLGHIASLGVDAVWLSP
CCCCCCCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCH
FFKSPMADMGYDVSDYRDVDPMFGSLEDFDALVTEAHRLGLKVVIDQVLSHSSDKHEWFV
HHCCCHHHCCCCCHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QSRASRDNPKADWYVWADTKPDGNAPNNWLSVFGGPAWEWDSTRRQYYMHNFLASQPDLN
HHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCC
FHNPEVQDALLDTVRFWLERGVDGFRLDTVNYYVHDRWLRSNPPLASSVAGTNGETNTYL
CCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCCCCCCEEE
YQEHLFDKTQPENLAFLRRFRGLLDEYPDRAAVGEIGDEGRSLQTLAAYTSGGDKLQMCY
EHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEHHHCCCCCCEEEEEE
TFDLLGPQFSAAHVRGCVEAFEQAVTDGWVCWAFSNHDVVRHVSRWTGPDGDADAVARFS
EEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
IMLLACLRGSICLYQGEELGLEEAELAYEDLRDPVGIRFWPGMKGRDGCRTPMVWEAGAD
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEECCCC
NAGFSTARPWLPVPASHRARATDVQNGSEQSVLSAYRSTLALRRRHPALVSGSIRFLDAE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCEEEEECC
GDVLAFIREGDGQRLLCVFNFAGEPGNWPLPPDIGVAAVLAGAAVVEEEALSLPALGCFL
CCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
GRLD
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]