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The map label for this gene is ywlC [H]

Identifier: 13476186

GI number: 13476186

Start: 6147838

End: 6148821

Strand: Direct

Name: ywlC [H]

Synonym: mlr7439

Alternate gene names: 13476186

Gene position: 6147838-6148821 (Clockwise)

Preceding gene: 13476182

Following gene: 13476187

Centisome position: 87.38

GC content: 68.19

Gene sequence:

>984_bases
GTGACGAGAGTGGCTGAGATACTTGCCGTCGGCGAGGCGTTGGAGCGGGCGCTGGCTTTGCTTGGGGATGGCGATGTCGT
CGCCATTCCGACGGAAACCGTCTACGGGCTAGCCGGCGACGCCACCAACGGCATCGGCGTGGCGCGCATCTTCGAGGCCA
AGGGGCGGCCGCGCTTCAATCCGCTGATCGCCCATGTCGCCGACATGGCGATGGCCGAGCGCATCGCGGTGTTCGATCCG
CTGTCGAAGAAACTCGCGCAGGCGTTCTGGCCGGGCCCGCTGACCCTGGTGCTGCCGCAGCGGCCTGGCAACGGCATCCA
TCCGCTGGTCACGGCCGGGCTCGACACGATCGCCTTGCGCATGCCGAGGGGCTTTGGCGGCGACCTCATCGCAAAGCTCG
GCCGGCCGCTTGCCGCGCCCAGCGCCAATTCCTCCGGCAGGATCAGCGCGACGACGGCACAAGCGGTGGCGGCCGATCTC
GGCGCCCGCATCAAACTGGTGGTCGATGGCGGCGCGACGCCGGTCGGGCTGGAATCGACCATCGTCAAGGCCGAAGGGGC
AGGAGTGCGCCTGCTCCGGCCTGGTGGCATCGCCGCCGAGGAGATCGAGGCGGCCATCGGCATGGAGCTGTTGCGCGGCG
GAGGGGCGGGCATCGAGGCGCCAGGCATGCTCGCCTCGCACTATGCGCCAGGTGCTGCCATGCGGCTCAATGCCGGAATG
GTCGGTGAGGGCGAAGCGTTGCTCGGCTTCGGCGGCAACCGGGCTGAAGGCTGGCGCAATGCCACAGCCTTCCTCAACCT
GTCAGCATCAGGTGACCTGCGCGAAGCGGCGAGCAATCTTTTCGCCTATATGCAGGAACTCGATCGCAGCGGTGCGCGCA
CCATCGCGGTGGAGACGATCCCCTTCGATGGGCTCGGCGAGGCCATCAACGACCGGCTCGCTCGCGCGGCCGCCCCTCGT
GACAATGCACAGCCCACAACATAG

Upstream 100 bases:

>100_bases
ATAGCATTTTAGGGATTGATAAATCGCCAAGCCCCTCTCGTGCCGAACAGCCGGCTTGCCCAACAGCCGCCATCCGTACT
ACGCAGCCGGCATCTGCGAG

Downstream 100 bases:

>100_bases
TTTTCCCGCATGACCGAAATTTTGCAAAAACTCGATCCCGCTCTCATCGACCGCTTCGCGGCGATCGTCGGTGACAAATA
CGCGCTGCGCGATGAGCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTRVAEILAVGEALERALALLGDGDVVAIPTETVYGLAGDATNGIGVARIFEAKGRPRFNPLIAHVADMAMAERIAVFDP
LSKKLAQAFWPGPLTLVLPQRPGNGIHPLVTAGLDTIALRMPRGFGGDLIAKLGRPLAAPSANSSGRISATTAQAVAADL
GARIKLVVDGGATPVGLESTIVKAEGAGVRLLRPGGIAAEEIEAAIGMELLRGGGAGIEAPGMLASHYAPGAAMRLNAGM
VGEGEALLGFGGNRAEGWRNATAFLNLSASGDLREAASNLFAYMQELDRSGARTIAVETIPFDGLGEAINDRLARAAAPR
DNAQPTT

Sequences:

>Translated_327_residues
MTRVAEILAVGEALERALALLGDGDVVAIPTETVYGLAGDATNGIGVARIFEAKGRPRFNPLIAHVADMAMAERIAVFDP
LSKKLAQAFWPGPLTLVLPQRPGNGIHPLVTAGLDTIALRMPRGFGGDLIAKLGRPLAAPSANSSGRISATTAQAVAADL
GARIKLVVDGGATPVGLESTIVKAEGAGVRLLRPGGIAAEEIEAAIGMELLRGGGAGIEAPGMLASHYAPGAAMRLNAGM
VGEGEALLGFGGNRAEGWRNATAFLNLSASGDLREAASNLFAYMQELDRSGARTIAVETIPFDGLGEAINDRLARAAAPR
DNAQPTT
>Mature_326_residues
TRVAEILAVGEALERALALLGDGDVVAIPTETVYGLAGDATNGIGVARIFEAKGRPRFNPLIAHVADMAMAERIAVFDPL
SKKLAQAFWPGPLTLVLPQRPGNGIHPLVTAGLDTIALRMPRGFGGDLIAKLGRPLAAPSANSSGRISATTAQAVAADLG
ARIKLVVDGGATPVGLESTIVKAEGAGVRLLRPGGIAAEEIEAAIGMELLRGGGAGIEAPGMLASHYAPGAAMRLNAGMV
GEGEALLGFGGNRAEGWRNATAFLNLSASGDLREAASNLFAYMQELDRSGARTIAVETIPFDGLGEAINDRLARAAAPRD
NAQPTT

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI17537239, Length=229, Percent_Identity=29.2576419213974, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=374, Percent_Identity=33.1550802139037, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI78707274, Length=144, Percent_Identity=36.1111111111111, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33480; Mature: 33349

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVAEILAVGEALERALALLGDGDVVAIPTETVYGLAGDATNGIGVARIFEAKGRPRFN
CCHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCCCEEEEEEECCCCCCCH
PLIAHVADMAMAERIAVFDPLSKKLAQAFWPGPLTLVLPQRPGNGIHPLVTAGLDTIALR
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCHHEEEEE
MPRGFGGDLIAKLGRPLAAPSANSSGRISATTAQAVAADLGARIKLVVDGGATPVGLEST
CCCCCCHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCCCE
IVKAEGAGVRLLRPGGIAAEEIEAAIGMELLRGGGAGIEAPGMLASHYAPGAAMRLNAGM
EEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEECCCC
VGEGEALLGFGGNRAEGWRNATAFLNLSASGDLREAASNLFAYMQELDRSGARTIAVETI
CCCCCEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEC
PFDGLGEAINDRLARAAAPRDNAQPTT
CCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TRVAEILAVGEALERALALLGDGDVVAIPTETVYGLAGDATNGIGVARIFEAKGRPRFN
CHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHEEECCCCCCCCCEEEEEEECCCCCCCH
PLIAHVADMAMAERIAVFDPLSKKLAQAFWPGPLTLVLPQRPGNGIHPLVTAGLDTIALR
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCHHEEEEE
MPRGFGGDLIAKLGRPLAAPSANSSGRISATTAQAVAADLGARIKLVVDGGATPVGLEST
CCCCCCHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCCCCCCE
IVKAEGAGVRLLRPGGIAAEEIEAAIGMELLRGGGAGIEAPGMLASHYAPGAAMRLNAGM
EEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEECCCC
VGEGEALLGFGGNRAEGWRNATAFLNLSASGDLREAASNLFAYMQELDRSGARTIAVETI
CCCCCEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEC
PFDGLGEAINDRLARAAAPRDNAQPTT
CCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]