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The map label for this gene is gsiC [H]

Identifier: 13476037

GI number: 13476037

Start: 5985629

End: 5986588

Strand: Reverse

Name: gsiC [H]

Synonym: mll7246

Alternate gene names: 13476037

Gene position: 5986588-5985629 (Counterclockwise)

Preceding gene: 13476038

Following gene: 13476036

Centisome position: 85.08

GC content: 63.44

Gene sequence:

>960_bases
GTGAACTATCTGATGCGACGACTGGCGACGTTTCCTCTCGTCCTGCTTGGCGTGTCCATCCTGGTCTTCGTGGCGATCCG
GATGGTGCCGGGCGATTCGATCACGGCGATGCTGGGCACCGAAGCCGGCCTGCTGACGCCGGCACAACGGGATTCGCTCG
CCGCCTACTTCGGCATCGACCAGCCCTGGTTCGTCCAGTACTGGCGCTGGATCGGCGGCATCCTGCACGGCAATTTCGGC
GTTTCCGTCACCTATGGCCGGCCGGTGCTCGACGTCATCCTCGAACGCTTCCCGCTGACGCTGGAATTGGCTCTGCTGTC
GATGATCATTGCGCTTGCCGTCGGCATGCCGGCGGGGATTTTTGCCGCCACGCACAATGAGAAACTATCGGATCTCGGCG
TGCGCATCGCCGCCATGATCGGCCAGTCGACGCCAAGCTTCGTGCTTGGCCTGCTGATCATCTACACGCTGTCGGCCGGC
TTCGGCGTGCTGCCGGCGATGGGCGAATTCGCGCCGCTCTGGCAGGATCCCTTGCGCAATCTCAGCCAGTTGATCCTGCC
CGCCATCACGCTGGGCTTTGCCTTCGCCGCGTCGGTCACGCGCATATCGCGTTCGGCGATGCTCGACGTTTTGAGCGACG
ATTACGTACGCACCGCGCGCAGCAAGGGCGCGTCGGCGCGCAGCGTCATCTGGCGGCATGCACTCCCCAATGCGCTGATC
CCGGTCGTAACACTGAGCGGCATCGAATTCGGCTATCTCCTGGGCGGCGCCGTCATCGTCGAGCAGATCTATGCCTTGCC
CGGCCTTGGTCGCATGGTGCTGGACGCCATCCTGCAGCGCGACTACGCGCTGGTGCAGGGAGCCGTGCTGTTCGTCGCCT
TCAATTTCATGATCGTCAATCTCTTGGTCGACCTCGCCTATGTCGCGCTCGATCCGCGTATCCGGCTGGGAGAGCAGTGA

Upstream 100 bases:

>100_bases
GCCGGCTTCGTGCCGACGCCGACCGGCACGCTGTTCAGCCTGAGCAAGGTTACCATCCAGCAGTAGCCGCCACAGGTATT
GGACAAGAGGACTTCTTCGC

Downstream 100 bases:

>100_bases
TGCGCATCCTGCGCGCCATCTTCGGCCATGGCAGCGGCCGCGTCGGCGGCGTCATCGTCGGCGTCTATTTGCTGGTCGCC
ATCCTCGGCCTGTTCGGGCT

Product: ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNYLMRRLATFPLVLLGVSILVFVAIRMVPGDSITAMLGTEAGLLTPAQRDSLAAYFGIDQPWFVQYWRWIGGILHGNFG
VSVTYGRPVLDVILERFPLTLELALLSMIIALAVGMPAGIFAATHNEKLSDLGVRIAAMIGQSTPSFVLGLLIIYTLSAG
FGVLPAMGEFAPLWQDPLRNLSQLILPAITLGFAFAASVTRISRSAMLDVLSDDYVRTARSKGASARSVIWRHALPNALI
PVVTLSGIEFGYLLGGAVIVEQIYALPGLGRMVLDAILQRDYALVQGAVLFVAFNFMIVNLLVDLAYVALDPRIRLGEQ

Sequences:

>Translated_319_residues
MNYLMRRLATFPLVLLGVSILVFVAIRMVPGDSITAMLGTEAGLLTPAQRDSLAAYFGIDQPWFVQYWRWIGGILHGNFG
VSVTYGRPVLDVILERFPLTLELALLSMIIALAVGMPAGIFAATHNEKLSDLGVRIAAMIGQSTPSFVLGLLIIYTLSAG
FGVLPAMGEFAPLWQDPLRNLSQLILPAITLGFAFAASVTRISRSAMLDVLSDDYVRTARSKGASARSVIWRHALPNALI
PVVTLSGIEFGYLLGGAVIVEQIYALPGLGRMVLDAILQRDYALVQGAVLFVAFNFMIVNLLVDLAYVALDPRIRLGEQ
>Mature_319_residues
MNYLMRRLATFPLVLLGVSILVFVAIRMVPGDSITAMLGTEAGLLTPAQRDSLAAYFGIDQPWFVQYWRWIGGILHGNFG
VSVTYGRPVLDVILERFPLTLELALLSMIIALAVGMPAGIFAATHNEKLSDLGVRIAAMIGQSTPSFVLGLLIIYTLSAG
FGVLPAMGEFAPLWQDPLRNLSQLILPAITLGFAFAASVTRISRSAMLDVLSDDYVRTARSKGASARSVIWRHALPNALI
PVVTLSGIEFGYLLGGAVIVEQIYALPGLGRMVLDAILQRDYALVQGAVLFVAFNFMIVNLLVDLAYVALDPRIRLGEQ

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=42.0886075949367, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=37.6854599406528, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1789888, Length=318, Percent_Identity=38.0503144654088, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=38.2089552238806, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=32.1766561514196, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=33.5849056603774, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788504, Length=279, Percent_Identity=26.8817204301075, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34578; Mature: 34578

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYLMRRLATFPLVLLGVSILVFVAIRMVPGDSITAMLGTEAGLLTPAQRDSLAAYFGID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHCCCCEECCC
QPWFVQYWRWIGGILHGNFGVSVTYGRPVLDVILERFPLTLELALLSMIIALAVGMPAGI
CHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHH
FAATHNEKLSDLGVRIAAMIGQSTPSFVLGLLIIYTLSAGFGVLPAMGEFAPLWQDPLRN
EEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCCHHCHHHHHHHHH
LSQLILPAITLGFAFAASVTRISRSAMLDVLSDDYVRTARSKGASARSVIWRHALPNALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
PVVTLSGIEFGYLLGGAVIVEQIYALPGLGRMVLDAILQRDYALVQGAVLFVAFNFMIVN
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVDLAYVALDPRIRLGEQ
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNYLMRRLATFPLVLLGVSILVFVAIRMVPGDSITAMLGTEAGLLTPAQRDSLAAYFGID
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHCCCCEECCC
QPWFVQYWRWIGGILHGNFGVSVTYGRPVLDVILERFPLTLELALLSMIIALAVGMPAGI
CHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHH
FAATHNEKLSDLGVRIAAMIGQSTPSFVLGLLIIYTLSAGFGVLPAMGEFAPLWQDPLRN
EEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHCCCHHCHHHHHHHHH
LSQLILPAITLGFAFAASVTRISRSAMLDVLSDDYVRTARSKGASARSVIWRHALPNALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHH
PVVTLSGIEFGYLLGGAVIVEQIYALPGLGRMVLDAILQRDYALVQGAVLFVAFNFMIVN
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVDLAYVALDPRIRLGEQ
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]