Click here to switch to the map view.

The map label for this gene is dctB [H]

Identifier: 13476030

GI number: 13476030

Start: 5977029

End: 5978834

Strand: Direct

Name: dctB [H]

Synonym: mlr7238

Alternate gene names: 13476030

Gene position: 5977029-5978834 (Clockwise)

Preceding gene: 13476028

Following gene: 13476031

Centisome position: 84.95

GC content: 66.22

Gene sequence:

>1806_bases
GTGGCCCGGCTGCGCGATGGCCGCTGGCTTGTTATCGTCATTGCTCTTGCGATCCTGGCGGGCGCGATCGCCATCGCTGG
GCGCATCGCCACCGGCCAGGCGACCAATGACCTGCGCGATAGCGCCCTTGCCGCCCTGCCGCTGGCGGCGGGAACCCTGA
CCGGCGAAATCGAAAAGCAGCGCCTGGTTCCCTTGGTACTGGCCCGCGACGATGCGGTGCGCGGTGCGCTGCGCCGGGCC
GGAAAGATGCAGGAAGCCGCCCTCAACGACAAGCTTAAGGCGATCGCCGGCGATGCCTCGGCATCCGCCATCTATGTCAT
CGATACTGCGGGCATCGCCATATCGGCCAGCAATGCCGGCGAGCCGACCAGCTTTGTCGGCATAGACTATAATTTCCGCC
ACTATTTCAACGAGGCGATGTCAAAAGGTTCGGCCAGCCAGTATGGCCTCGGCACGATCAGTGGCCGGCCGGGTCTCTAC
CTTGCCAGCCGCGTCGACGACAATGGCAAGCCGCTGGGCGTAGCGGTGCTGAAGGTCGAGCTTGACGGCGTCGAGGCTAA
TTGGCGCTCCAGCGGTTTTCTTGTTTTCGTCACCGACGAACGCGGCGTCGTGCTGGCAACCAGCCAGCCCGAATGGCGGT
TTCATGCGCTGGCGCCGCTCTCCGCGGAAGACGCCGCAACTGCCCATGAGCAGCTGCAACTGCCGGACGCCGCCTTCGAA
CCTCTGCCGATACGACGCGGTGCCGGTGATGGCCTGGCGACCATCGACGGCCCCGGCAAGCCGCGCCAGTTTGTCGAGGT
GGTGCAGGATCTGTCCGGTGCGGTTCCCGGCTGGCGCCTTTGGCTGCTGACGCCGGCGGATCCCGCTCTCTCGTCCGCCG
CCAACACGGCGCGGCTGACGACGCTGCTCGGGCTGCTGCTGACCGGCCTGCTTGCCTACGTATTCACAAGGCGCCGCCGC
ACACGCCGTCTGCGGCAGGAGGCGCTGGCGCGCATGAATGCCGAGCTGGAAAGCCGGGTTAGCACACGGACAGCCGAACT
GACCCGCTCCAACATCGCGCTCGCCGGCGAGATCGCCGAGCGTGAAAATGCCGAAGCCAAGGTCCGCCGGCTGCGCGACG
ATCTTGCCCAGGCCAACAGGCTCTCCATCCTCGGCCAGATCGCTGCCGGCGTGGCGCATGAGATCAACCAGCCGGTCGCT
GCGATCCGCACCTATGCCGAGAATGCCGGCCGCTTCCTCGAAACCGGCAAGACCGAACCGGCGAGCGGCAATCTGACCTC
GATCGTCTCGATGACCGAACGCATCGGCGCCATCACCAACACGCTGCGCACCTTCGCGCGCCGGCCCGGTGTCGCCGCGT
CGCCACTGCCGGTGCGCGAGGCGATCGACGGCGCGCTATCGCTACTCTCCGGCCGCATTCGCGATTCCGGTGTCACCATC
GTCAAGCCGCTCGGTACCGCCTCGCCGATGGTGATGGCAAGCCGCATCCGGCTGGAGCAGATCCTCGTCAACCTGTTGCA
GAACGCGCTCGACGCCATGAAGGACCAGCCCGATCCCCGCATCGAGATCGACCTCGCCCAGCGCGACGACCGGGTGTTGA
TTTCGGTGCGCGACAACGGTCCCGGTCTTGGGCCGGAAGCGGCTGGCAATCTGTTCATGCCGTTCCAGACCACCAAGGAG
AAGGGGCTCGGCCTCGGGCTGGTGATCTCGCAGGAGATCGCCCAGGAATTGGGCGGCACGCTCCGGCTCGATCCCGACAG
CACCAGAGGCGCGTCCTTCACCATCGATTTGAGGCGAATCGAATGA

Upstream 100 bases:

>100_bases
AGAGTGACGGCAAGGCCGCGAGAAAAGAAGGAGAGGGCAGACGTCGCAAGCAAGCACCGATAGGCGCGCCGCGGCCGGTG
GCGACTTGCTCCGCGAGGCT

Downstream 100 bases:

>100_bases
ACGAGGGATCACGGAGGGTGGCGCTCGTCGAGGACGATGCCGACCTGCTGCACGCCACCACGCAATTGCTCGAGCTCGCC
GGTTTCACCGTGGTTGCGCG

Product: two-component C4-dicarboxylate transport system, sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MARLRDGRWLVIVIALAILAGAIAIAGRIATGQATNDLRDSALAALPLAAGTLTGEIEKQRLVPLVLARDDAVRGALRRA
GKMQEAALNDKLKAIAGDASASAIYVIDTAGIAISASNAGEPTSFVGIDYNFRHYFNEAMSKGSASQYGLGTISGRPGLY
LASRVDDNGKPLGVAVLKVELDGVEANWRSSGFLVFVTDERGVVLATSQPEWRFHALAPLSAEDAATAHEQLQLPDAAFE
PLPIRRGAGDGLATIDGPGKPRQFVEVVQDLSGAVPGWRLWLLTPADPALSSAANTARLTTLLGLLLTGLLAYVFTRRRR
TRRLRQEALARMNAELESRVSTRTAELTRSNIALAGEIAERENAEAKVRRLRDDLAQANRLSILGQIAAGVAHEINQPVA
AIRTYAENAGRFLETGKTEPASGNLTSIVSMTERIGAITNTLRTFARRPGVAASPLPVREAIDGALSLLSGRIRDSGVTI
VKPLGTASPMVMASRIRLEQILVNLLQNALDAMKDQPDPRIEIDLAQRDDRVLISVRDNGPGLGPEAAGNLFMPFQTTKE
KGLGLGLVISQEIAQELGGTLRLDPDSTRGASFTIDLRRIE

Sequences:

>Translated_601_residues
MARLRDGRWLVIVIALAILAGAIAIAGRIATGQATNDLRDSALAALPLAAGTLTGEIEKQRLVPLVLARDDAVRGALRRA
GKMQEAALNDKLKAIAGDASASAIYVIDTAGIAISASNAGEPTSFVGIDYNFRHYFNEAMSKGSASQYGLGTISGRPGLY
LASRVDDNGKPLGVAVLKVELDGVEANWRSSGFLVFVTDERGVVLATSQPEWRFHALAPLSAEDAATAHEQLQLPDAAFE
PLPIRRGAGDGLATIDGPGKPRQFVEVVQDLSGAVPGWRLWLLTPADPALSSAANTARLTTLLGLLLTGLLAYVFTRRRR
TRRLRQEALARMNAELESRVSTRTAELTRSNIALAGEIAERENAEAKVRRLRDDLAQANRLSILGQIAAGVAHEINQPVA
AIRTYAENAGRFLETGKTEPASGNLTSIVSMTERIGAITNTLRTFARRPGVAASPLPVREAIDGALSLLSGRIRDSGVTI
VKPLGTASPMVMASRIRLEQILVNLLQNALDAMKDQPDPRIEIDLAQRDDRVLISVRDNGPGLGPEAAGNLFMPFQTTKE
KGLGLGLVISQEIAQELGGTLRLDPDSTRGASFTIDLRRIE
>Mature_600_residues
ARLRDGRWLVIVIALAILAGAIAIAGRIATGQATNDLRDSALAALPLAAGTLTGEIEKQRLVPLVLARDDAVRGALRRAG
KMQEAALNDKLKAIAGDASASAIYVIDTAGIAISASNAGEPTSFVGIDYNFRHYFNEAMSKGSASQYGLGTISGRPGLYL
ASRVDDNGKPLGVAVLKVELDGVEANWRSSGFLVFVTDERGVVLATSQPEWRFHALAPLSAEDAATAHEQLQLPDAAFEP
LPIRRGAGDGLATIDGPGKPRQFVEVVQDLSGAVPGWRLWLLTPADPALSSAANTARLTTLLGLLLTGLLAYVFTRRRRT
RRLRQEALARMNAELESRVSTRTAELTRSNIALAGEIAERENAEAKVRRLRDDLAQANRLSILGQIAAGVAHEINQPVAA
IRTYAENAGRFLETGKTEPASGNLTSIVSMTERIGAITNTLRTFARRPGVAASPLPVREAIDGALSLLSGRIRDSGVTIV
KPLGTASPMVMASRIRLEQILVNLLQNALDAMKDQPDPRIEIDLAQRDDRVLISVRDNGPGLGPEAAGNLFMPFQTTKEK
GLGLGLVISQEIAQELGGTLRLDPDSTRGASFTIDLRRIE

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=31.25, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=28.1385281385281, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789149, Length=282, Percent_Identity=24.113475177305, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081816, Length=282, Percent_Identity=26.9503546099291, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64142; Mature: 64011

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLRDGRWLVIVIALAILAGAIAIAGRIATGQATNDLRDSALAALPLAAGTLTGEIEKQ
CCCCCCCCCHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
RLVPLVLARDDAVRGALRRAGKMQEAALNDKLKAIAGDASASAIYVIDTAGIAISASNAG
HCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCC
EPTSFVGIDYNFRHYFNEAMSKGSASQYGLGTISGRPGLYLASRVDDNGKPLGVAVLKVE
CCCEEEEECCHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEECCCCCCEEEEEEEEEE
LDGVEANWRSSGFLVFVTDERGVVLATSQPEWRFHALAPLSAEDAATAHEQLQLPDAAFE
ECCCCCCCCCCCEEEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCC
PLPIRRGAGDGLATIDGPGKPRQFVEVVQDLSGAVPGWRLWLLTPADPALSSAANTARLT
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
TLLGLLLTGLLAYVFTRRRRTRRLRQEALARMNAELESRVSTRTAELTRSNIALAGEIAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHH
RENAEAKVRRLRDDLAQANRLSILGQIAAGVAHEINQPVAAIRTYAENAGRFLETGKTEP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCC
ASGNLTSIVSMTERIGAITNTLRTFARRPGVAASPLPVREAIDGALSLLSGRIRDSGVTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEE
VKPLGTASPMVMASRIRLEQILVNLLQNALDAMKDQPDPRIEIDLAQRDDRVLISVRDNG
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCC
PGLGPEAAGNLFMPFQTTKEKGLGLGLVISQEIAQELGGTLRLDPDSTRGASFTIDLRRI
CCCCCCCCCCEEECCCCCCCCCCEEEEEHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEC
E
C
>Mature Secondary Structure 
ARLRDGRWLVIVIALAILAGAIAIAGRIATGQATNDLRDSALAALPLAAGTLTGEIEKQ
CCCCCCCCHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
RLVPLVLARDDAVRGALRRAGKMQEAALNDKLKAIAGDASASAIYVIDTAGIAISASNAG
HCCEEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEECCCCC
EPTSFVGIDYNFRHYFNEAMSKGSASQYGLGTISGRPGLYLASRVDDNGKPLGVAVLKVE
CCCEEEEECCHHHHHHHHHHCCCCCCCCCCEEECCCCCEEEEEECCCCCCEEEEEEEEEE
LDGVEANWRSSGFLVFVTDERGVVLATSQPEWRFHALAPLSAEDAATAHEQLQLPDAAFE
ECCCCCCCCCCCEEEEEECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCC
PLPIRRGAGDGLATIDGPGKPRQFVEVVQDLSGAVPGWRLWLLTPADPALSSAANTARLT
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
TLLGLLLTGLLAYVFTRRRRTRRLRQEALARMNAELESRVSTRTAELTRSNIALAGEIAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHH
RENAEAKVRRLRDDLAQANRLSILGQIAAGVAHEINQPVAAIRTYAENAGRFLETGKTEP
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCCCCCC
ASGNLTSIVSMTERIGAITNTLRTFARRPGVAASPLPVREAIDGALSLLSGRIRDSGVTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEE
VKPLGTASPMVMASRIRLEQILVNLLQNALDAMKDQPDPRIEIDLAQRDDRVLISVRDNG
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCC
PGLGPEAAGNLFMPFQTTKEKGLGLGLVISQEIAQELGGTLRLDPDSTRGASFTIDLRRI
CCCCCCCCCCEEECCCCCCCCCCEEEEEHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]