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The map label for this gene is lacK [H]

Identifier: 13476028

GI number: 13476028

Start: 5974991

End: 5975320

Strand: Direct

Name: lacK [H]

Synonym: msr7236

Alternate gene names: 13476028

Gene position: 5974991-5975320 (Clockwise)

Preceding gene: 13476027

Following gene: 13476030

Centisome position: 84.92

GC content: 65.45

Gene sequence:

>330_bases
ATGGCAGCCTGGCAGCCCGTATGCCTGTCGGTCCAAGCACGTTTCCTGAAGCGAGGAGGGACTTCAACGGCTGAGCTCAT
GCTCGACGGCCCGCGCATCAACCAGGTCGATCCGTCCGAGCGCGGCCTTGCCTTGGTGTTCCAGTCCTATGCGCTCTATC
CGCATATGACGGTGGCGGAAAACATGGGCTTTGCGCCTGCTGGTGGCCGAGCGCGACGCCCGACACCACCCCACAGCTCC
ATCGCCATGCAGGTCGACCCGTGCCACTGCCATCTCTTCGCTGCCGATGGCAGAGCGCTGGCGCCGCTCGGCAAGATCCG
CGCCGCCTGA

Upstream 100 bases:

>100_bases
CAACGCGCCATGCGCGCCTATCGCGACGTGCCGGTGGTTCAGGCCCAGCTCGGCCGCCACGCCGGGCTGGTCGGCGCCGC
CAGCCTTGTCCTGTTCGACG

Downstream 100 bases:

>100_bases
CATCGTCACCCACATGAAAATGGCCGGAGGCATCGCTGCCTCCGGCCATTCGTATCGCTAAACGACCGTGCGAATTACTC
GGCGGGAACGATATCCGCCG

Product: ATP-binding protein lacK

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MAAWQPVCLSVQARFLKRGGTSTAELMLDGPRINQVDPSERGLALVFQSYALYPHMTVAENMGFAPAGGRARRPTPPHSS
IAMQVDPCHCHLFAADGRALAPLGKIRAA

Sequences:

>Translated_109_residues
MAAWQPVCLSVQARFLKRGGTSTAELMLDGPRINQVDPSERGLALVFQSYALYPHMTVAENMGFAPAGGRARRPTPPHSS
IAMQVDPCHCHLFAADGRALAPLGKIRAA
>Mature_108_residues
AAWQPVCLSVQARFLKRGGTSTAELMLDGPRINQVDPSERGLALVFQSYALYPHMTVAENMGFAPAGGRARRPTPPHSSI
AMQVDPCHCHLFAADGRALAPLGKIRAA

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for energy coupling to the transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR008995
- InterPro:   IPR005116 [H]

Pfam domain/function: PF00005 ABC_tran; PF03459 TOBE [H]

EC number: NA

Molecular weight: Translated: 11698; Mature: 11566

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAWQPVCLSVQARFLKRGGTSTAELMLDGPRINQVDPSERGLALVFQSYALYPHMTVAE
CCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEHHCCCCCCCHHC
NMGFAPAGGRARRPTPPHSSIAMQVDPCHCHLFAADGRALAPLGKIRAA
CCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCEECCCCCCCCC
>Mature Secondary Structure 
AAWQPVCLSVQARFLKRGGTSTAELMLDGPRINQVDPSERGLALVFQSYALYPHMTVAE
CCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEHHCCCCCCCHHC
NMGFAPAGGRARRPTPPHSSIAMQVDPCHCHLFAADGRALAPLGKIRAA
CCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]