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The map label for this gene is exsH [H]

Identifier: 13475631

GI number: 13475631

Start: 5543137

End: 5544624

Strand: Reverse

Name: exsH [H]

Synonym: mll6750

Alternate gene names: 13475631

Gene position: 5544624-5543137 (Counterclockwise)

Preceding gene: 13475632

Following gene: 13475628

Centisome position: 78.8

GC content: 60.15

Gene sequence:

>1488_bases
ATGACAACCCTCCACTATGCCTCGGGTGGGTCGGCCTCCGAGGTCGCAACCGCCGGGTTCAATCTTGTCGACGTTTCATC
CGTGGACGAACTCAACGCCTTACCGGCTGGCACGAAAGGTCTGGTCTGGCTCGATGAAGCCAATGGCGCAACCTCGTCCT
TCATTCAGAAAGTCACGCCCTTCATCGGCAATCCGAATGTGTTCGGCTTCTTCCTCGTCGACGAGCCCGATCCCACGGGC
AAATGGGGAACCTATGCCACAGCCGACAATCTGAAGGCGGAATCCGACTGGATCCACACCAACCTGCCCGGCGCCAAGAC
CTTCATCACCATGATGAACATGGGGTCTTCGGCTGATCCCGATTTTTCAAACACTTTCAATCCCGCCAACACGCATATCG
ACTATTACGGCGTGGATCCCTACCCGGTGCGCACCGGCACAAGCACCGTCGACTACAACATGATCGACAGGACCGTGGCC
GCGGCGGTCGCCTCGGGCGTTCCGCTCAGCCAGATCGTTCCGGTTTATCAGACGTTCGGCGGCGGCAACTACACCACCGA
TACGGGCGGCCAATATGTCCTTCCCAGCGTCGCCCAGGAGCAGACCATGCTGGACCACTGGGCCAAGGTGGCGCCATCGC
CCGCCTTCGACTATGCCTATGCCTGGGGTTCTCAACAGGGCGACACCGCGCTTGGCAACTCGCCAGCGCTGCAAGCCTTG
TTCCTTCAGCACAATCAGGGCACCACCAGCGTGCCTTCAACCGGCGAAACGACTCCGCCCACCAGCACGGTGCCCCCGCC
CAGCACGGTGCCCCCAACCAGTACCGTGCCTTCGAGCAGCGATCACACTTTCTACGGCACGGGCGGCGCGGATGCGCTTC
ACGGCACCACCGGCGCCGATACGATGGTCGGTGGTGGCTACAACGACACCTACTATGTCAACAACGTCGGCGACAAGGTG
GTGGAACTGGCGGGCGGCGGCAACGATACCGTGCTGGCATCGGTGAGTTACGCGCTGTCGGCCGGCTCGGAGATCGAACA
TCTCGCCATCGCGAGCAAGTCCGACACTACAACCATGAACCTCAAGGGAAACGAGTTCTCCCAAACCATAGACGGCAATG
CCGGCAACAACGTCATCAACGGCGGTGGCGGGAAAGACGTCCTGACGGGAAATGGGGGCCATGACTACTTTTTCTTCAAT
GCCGCCCTCAAGACCGGCAATGTCGATAAGATCACCGATTTTAATGTGGCCCAGGACAAGATCGTGCTCGACCACAGTGT
GTTTACCGGCCTTCAAACAGGCGCCCTTCCCACCTCGGCGTTCCACGAAGGCAGGGGTGCGCACAGCAGCGGCGATCACA
TCATCTACAACAGTTCGACCGGCGCCCTGTCTTTCGACAGCGACGGCGCGGGTGGCGCACATCAGATCCAGTTTGCCACT
CTATCTCCGCATCTGTCTTTGACGGCGTCCTCGTTCATCGTAGCGTGA

Upstream 100 bases:

>100_bases
TCAACGATTCTATCAATGGGCGCCGGTATTTGATTTGGCCCTAATATATCCTTTCCAATAGGCAGGCACTGGGGCTATCG
AATCAGACGAAGGAAATTGC

Downstream 100 bases:

>100_bases
GCCTTGGGGAACGTCAGACCCTGATCACAAGGGTCTGACGTTTTCTTGATTATACATAAATATACTTCGGTGAAATACTT
TGATGGAACGAACCGCTCCA

Product: HlyA protein

Products: NA

Alternate protein names: Succinoglycan biosynthesis protein exsH [H]

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTTLHYASGGSASEVATAGFNLVDVSSVDELNALPAGTKGLVWLDEANGATSSFIQKVTPFIGNPNVFGFFLVDEPDPTG
KWGTYATADNLKAESDWIHTNLPGAKTFITMMNMGSSADPDFSNTFNPANTHIDYYGVDPYPVRTGTSTVDYNMIDRTVA
AAVASGVPLSQIVPVYQTFGGGNYTTDTGGQYVLPSVAQEQTMLDHWAKVAPSPAFDYAYAWGSQQGDTALGNSPALQAL
FLQHNQGTTSVPSTGETTPPTSTVPPPSTVPPTSTVPSSSDHTFYGTGGADALHGTTGADTMVGGGYNDTYYVNNVGDKV
VELAGGGNDTVLASVSYALSAGSEIEHLAIASKSDTTTMNLKGNEFSQTIDGNAGNNVINGGGGKDVLTGNGGHDYFFFN
AALKTGNVDKITDFNVAQDKIVLDHSVFTGLQTGALPTSAFHEGRGAHSSGDHIIYNSSTGALSFDSDGAGGAHQIQFAT
LSPHLSLTASSFIVA

Sequences:

>Translated_495_residues
MTTLHYASGGSASEVATAGFNLVDVSSVDELNALPAGTKGLVWLDEANGATSSFIQKVTPFIGNPNVFGFFLVDEPDPTG
KWGTYATADNLKAESDWIHTNLPGAKTFITMMNMGSSADPDFSNTFNPANTHIDYYGVDPYPVRTGTSTVDYNMIDRTVA
AAVASGVPLSQIVPVYQTFGGGNYTTDTGGQYVLPSVAQEQTMLDHWAKVAPSPAFDYAYAWGSQQGDTALGNSPALQAL
FLQHNQGTTSVPSTGETTPPTSTVPPPSTVPPTSTVPSSSDHTFYGTGGADALHGTTGADTMVGGGYNDTYYVNNVGDKV
VELAGGGNDTVLASVSYALSAGSEIEHLAIASKSDTTTMNLKGNEFSQTIDGNAGNNVINGGGGKDVLTGNGGHDYFFFN
AALKTGNVDKITDFNVAQDKIVLDHSVFTGLQTGALPTSAFHEGRGAHSSGDHIIYNSSTGALSFDSDGAGGAHQIQFAT
LSPHLSLTASSFIVA
>Mature_494_residues
TTLHYASGGSASEVATAGFNLVDVSSVDELNALPAGTKGLVWLDEANGATSSFIQKVTPFIGNPNVFGFFLVDEPDPTGK
WGTYATADNLKAESDWIHTNLPGAKTFITMMNMGSSADPDFSNTFNPANTHIDYYGVDPYPVRTGTSTVDYNMIDRTVAA
AVASGVPLSQIVPVYQTFGGGNYTTDTGGQYVLPSVAQEQTMLDHWAKVAPSPAFDYAYAWGSQQGDTALGNSPALQALF
LQHNQGTTSVPSTGETTPPTSTVPPPSTVPPTSTVPSSSDHTFYGTGGADALHGTTGADTMVGGGYNDTYYVNNVGDKVV
ELAGGGNDTVLASVSYALSAGSEIEHLAIASKSDTTTMNLKGNEFSQTIDGNAGNNVINGGGGKDVLTGNGGHDYFFFNA
ALKTGNVDKITDFNVAQDKIVLDHSVFTGLQTGALPTSAFHEGRGAHSSGDHIIYNSSTGALSFDSDGAGGAHQIQFATL
SPHLSLTASSFIVA

Specific function: Cleaves high molecular weight succinoglycan to yield LMW succinoglycan. Dynamically regulate the molecular weight distribution of succinoglycan by cleaving nascent succinoglycan only during a limited period after its synthesis, perhaps before it undergoes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Probably by a type-III secretion system [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR000757
- InterPro:   IPR011049 [H]

Pfam domain/function: PF00722 Glyco_hydro_16 [H]

EC number: NA

Molecular weight: Translated: 51340; Mature: 51209

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLHYASGGSASEVATAGFNLVDVSSVDELNALPAGTKGLVWLDEANGATSSFIQKVTP
CCEEEECCCCCHHHHHHCCCCEEECCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHC
FIGNPNVFGFFLVDEPDPTGKWGTYATADNLKAESDWIHTNLPGAKTFITMMNMGSSADP
CCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCEEECCCCCHHEEEEEECCCCCCCC
DFSNTFNPANTHIDYYGVDPYPVRTGTSTVDYNMIDRTVAAAVASGVPLSQIVPVYQTFG
CCCCCCCCCCCEEEEECCCCEEECCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
GGNYTTDTGGQYVLPSVAQEQTMLDHWAKVAPSPAFDYAYAWGSQQGDTALGNSPALQAL
CCCEECCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEEE
FLQHNQGTTSVPSTGETTPPTSTVPPPSTVPPTSTVPSSSDHTFYGTGGADALHGTTGAD
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
TMVGGGYNDTYYVNNVGDKVVELAGGGNDTVLASVSYALSAGSEIEHLAIASKSDTTTMN
CEECCCCCCCEEEECCCCEEEEEECCCCCEEEEEEEHHHCCCCCEEEEEEECCCCCEEEE
LKGNEFSQTIDGNAGNNVINGGGGKDVLTGNGGHDYFFFNAALKTGNVDKITDFNVAQDK
ECCCCHHHCCCCCCCCCEEECCCCCCEEECCCCCEEEEEEEEEECCCCCCEECCCCCCCE
IVLDHSVFTGLQTGALPTSAFHEGRGAHSSGDHIIYNSSTGALSFDSDGAGGAHQIQFAT
EEEEHHHHHCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCCCCEEEEEEE
LSPHLSLTASSFIVA
ECCCEEEECCEEEEC
>Mature Secondary Structure 
TTLHYASGGSASEVATAGFNLVDVSSVDELNALPAGTKGLVWLDEANGATSSFIQKVTP
CEEEECCCCCHHHHHHCCCCEEECCCCHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHC
FIGNPNVFGFFLVDEPDPTGKWGTYATADNLKAESDWIHTNLPGAKTFITMMNMGSSADP
CCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCEEECCCCCHHEEEEEECCCCCCCC
DFSNTFNPANTHIDYYGVDPYPVRTGTSTVDYNMIDRTVAAAVASGVPLSQIVPVYQTFG
CCCCCCCCCCCEEEEECCCCEEECCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
GGNYTTDTGGQYVLPSVAQEQTMLDHWAKVAPSPAFDYAYAWGSQQGDTALGNSPALQAL
CCCEECCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCEEEE
FLQHNQGTTSVPSTGETTPPTSTVPPPSTVPPTSTVPSSSDHTFYGTGGADALHGTTGAD
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
TMVGGGYNDTYYVNNVGDKVVELAGGGNDTVLASVSYALSAGSEIEHLAIASKSDTTTMN
CEECCCCCCCEEEECCCCEEEEEECCCCCEEEEEEEHHHCCCCCEEEEEEECCCCCEEEE
LKGNEFSQTIDGNAGNNVINGGGGKDVLTGNGGHDYFFFNAALKTGNVDKITDFNVAQDK
ECCCCHHHCCCCCCCCCEEECCCCCCEEECCCCCEEEEEEEEEECCCCCCEECCCCCCCE
IVLDHSVFTGLQTGALPTSAFHEGRGAHSSGDHIIYNSSTGALSFDSDGAGGAHQIQFAT
EEEEHHHHHCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCEEEECCCCCCCCEEEEEEE
LSPHLSLTASSFIVA
ECCCEEEECCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11902715; 11481431; 9560202 [H]