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The map label for this gene is tycC [H]

Identifier: 13475632

GI number: 13475632

Start: 5544925

End: 5547696

Strand: Reverse

Name: tycC [H]

Synonym: mll6752

Alternate gene names: 13475632

Gene position: 5547696-5544925 (Counterclockwise)

Preceding gene: 13475639

Following gene: 13475631

Centisome position: 78.85

GC content: 61.54

Gene sequence:

>2772_bases
GTGTTGGAGACGTCGGGGTACCCGCGTTTAGAAAGCCGTTTTCCACGCGCCTTGCCATCCGTTGGCGGACCGACAACGGA
TCAAGATGTTGTGATGCTGCGCGGCAACGGCCCTCCTGACGGCTTCACATGGAAACAGGCCTCTGCCCGCCCTCTGGATA
TGGACGGACCAACCACCCGTCTCTTCCCGCGGATGGGCGACGGCTTCTCCGAAAAATCGGCGTTCTCGCACCTGGAGCGG
GTTGTCGAAAAATACCCGGCAAAGATCGCGATCAGTGACGGCTCTGCGTCCCTCAGCTTTTCCGAACTGCTCAACGCCGT
CCAAAACCTGGCGGGTGCGATTGCCGGTTCGACCCCACCAGGCAAGGCGGTCGGGATCCTCATCGGAAATACGCTCTGGT
ATCCGGTGGCCATGCTCGCCGCCATGCGGGCCGGCAGGCCCGCCGTGCCGTTGAACCCCCGGGATCCATTTCAGCGCCTC
GCCGCAATTTCCACCAGCGCGCGGCTGGCTGCGATCATCAAGCCAGGGCCGGGCAAGCCGGCAGGCTGGCCGAATGCCTC
CTCGCTTGAATGGATCGATGCGGCAAGTTGCATGGCCGCAACGCCGGATGGCGGCCTATCGGCGTTGCCGTCCGAAGTGT
CGGTCGATGCTCCGGCAATCGTTCTGTACACGTCAGGCAGCACCGGGGCGCCGAAAGGCGTCGTGAACAGCCAACGGGCA
ATCCTCCAACGCGTTCAGCAATATGTCGATGCCTGCCACTTCGGCCCCGACGACGTGTTCATGCCGCTGACCGGGCCGGC
GACGATCGCGGGATGCCGCGAGATGATGACCCCGATGCTATGCGGCGCCACATTGTACCTCTCGGATATAGAGAGTGCCG
GTATTCGCGCCGCCCGCGACAATTTCGAGAAATGGCGGGTGACGGTCGTCTATCTCGTGCCGGCGCTGCTGCGTGTGTTG
ATGAATGGTTCTGCGCCCGACACATTCTCTTCCTTGCGGATCGTGCGGGTCGGCGGAGAAAAGATTCTATGGTCCGATAT
CGACCGGCTCCGCGACAGCGTTCACGAGTCCTGCCTTGTCCAGATCAGCTATTCGTCCACGGAAACGACCGGCACGCAAT
GGTTCCTGCCGAGGGGCTACCAGGAACGCGGCGCAACGGTCCCGGTTGGCTTCGTGCTGCCCGGCATCGAATACACCATC
GTGGATGAGAACGCATGCGAGGTCGCCCCGGGCGATGAAGGAGAGTTGCTGATCAGAAGCAATTACACCACGCTTGGCTA
CTGGGTGGATGGGGAAAACGTCCCTCTTCAGGCGAACTCCGGCAACCCCATGCTTCGAACCTTCGCAACGGGTGATCTGG
TCAAGGTCGACGACACCGGAATGATGTGGATCGTCGGGCGAAAGGGACGCCAGATCAAAATAAACGGAAGGCGGGTCGAA
CCTGCCGAACTGGAACTCGTCCTGCGCCGGGCGCCTCAGGTGGATGATGCCGTTGCGGTGGTGACGGACGCGAACGAACT
GGTGGCCTTTGTCGTCCCCGCGAGACCTGGTGCAAGCGAGCTCATTGCTGAATTGCGCGACCTGATCAGGACGGCCCTGC
CGCCGGCTGTTCACCCGACGCGCCTGCATAGTGTTGCCGAGATACCGCGGCTCAAAGGCGGCAAGGTCGACGGCGTCAAG
CTACGGGAACTGGATCGCGCACTGAACGCGCAAGACGCCCAGAACACGCCCATGGCCCGGCAGGCGGCAAACCCGCTTGA
TATCGAAGGCACCGCGGCGGCCGTATGGGAGAGGATTCTCCCGGGCAAAAGGACAGCTGGCAGCCGTTGGGACGATGCCG
GCGGCGATTCGTTGAAATTGCTGCAATTCGTCATGGAACTGGAGACGGCTCTGGGGCGGGAACTCAACCTGGACGCGTTC
ACCGTCGGGATGAGCTTTGCCGATGTCGTCCGGGCAGCGTCTCCAGGGCAAGACACAAGCAGCTCGCTTGTCGAGGCTTC
CGACCCGAGACCCGTTTTGTTCATCGTGCCTGGATCGATCGGCTACGGTCCAAGCCTGGCGGCCTTCGGTGCCGAGATGG
GCAAAGTCGCCAGGGTTGTTGCCATCCGCTACGGGGATCTGAACGACCTGCTGAGGGGACATGGCACGATACCGCGGATG
GTGGATGCGGTTGTCGACCAGATCAGCCAGGTCCAGCCTGATGGCGATGTGAAGCTGATCGGCTATTCGCTTGGCGGCGG
CGTCGCGTTCGAAGTTGCCGCCAAGCTTGTTGCCGCCGGTCGGTCGGTCACGTTCCTGGGAATCCTCGACACCAATATCG
GGCCTGGACAGCACAATTATCGTGAAAGACTCGCACGCACTGCCCAGCGCATCCGCACGCATCGAGTGACGGTGGATCGC
ATGATTTTGCGGGCTCTGGCAAAATTGTTTGCCCAATTTGGCGCCGAGGCTGTGCTTGCGAGGGGCATCGACTGGCTGAA
ATGGAGGAGCTTCGCCAGAACACGATTCATCTTGCGCCTTGAGCTCGAAGAAGTCCTGCGGATGCGCGCATTTGGCCAAT
GGCTCGCGCAACCGAAGCCCACATTGCCGATTACCGCCACCCTGTTTCGATGCAGGCGTACAGGCGTTCCGTCAGACCTT
GGCTGGAGTGCTTTCGTCACCGGCCTAAACATAATTCCGATCGTCGGCGGGCACCTGGACATGCTCGTTGAACCCTATCT
CGGCCACAACCGCCCGCTGATAGAAAGAGCCTTTGTGGTTAGCGGCGAATAG

Upstream 100 bases:

>100_bases
CGGATCGATGAGTTGAGCGGGAACTCATTCGTTCTAACGATGCCAGGGCCGACATGGTCGCGTAGGACACGGCAAGGCCA
ATCAGCAAAACAAGGGGGCT

Downstream 100 bases:

>100_bases
CGGGTGATTCGCACACCCGGAGGCTGAATCGAGACAGGATGCTCGTGTATCTTGCTGACGGATCCACAACAAATCCGCTG
TCACTGCGGCCGTAGAGAGA

Product: CDA peptide synthetase III

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 923; Mature: 923

Protein sequence:

>923_residues
MLETSGYPRLESRFPRALPSVGGPTTDQDVVMLRGNGPPDGFTWKQASARPLDMDGPTTRLFPRMGDGFSEKSAFSHLER
VVEKYPAKIAISDGSASLSFSELLNAVQNLAGAIAGSTPPGKAVGILIGNTLWYPVAMLAAMRAGRPAVPLNPRDPFQRL
AAISTSARLAAIIKPGPGKPAGWPNASSLEWIDAASCMAATPDGGLSALPSEVSVDAPAIVLYTSGSTGAPKGVVNSQRA
ILQRVQQYVDACHFGPDDVFMPLTGPATIAGCREMMTPMLCGATLYLSDIESAGIRAARDNFEKWRVTVVYLVPALLRVL
MNGSAPDTFSSLRIVRVGGEKILWSDIDRLRDSVHESCLVQISYSSTETTGTQWFLPRGYQERGATVPVGFVLPGIEYTI
VDENACEVAPGDEGELLIRSNYTTLGYWVDGENVPLQANSGNPMLRTFATGDLVKVDDTGMMWIVGRKGRQIKINGRRVE
PAELELVLRRAPQVDDAVAVVTDANELVAFVVPARPGASELIAELRDLIRTALPPAVHPTRLHSVAEIPRLKGGKVDGVK
LRELDRALNAQDAQNTPMARQAANPLDIEGTAAAVWERILPGKRTAGSRWDDAGGDSLKLLQFVMELETALGRELNLDAF
TVGMSFADVVRAASPGQDTSSSLVEASDPRPVLFIVPGSIGYGPSLAAFGAEMGKVARVVAIRYGDLNDLLRGHGTIPRM
VDAVVDQISQVQPDGDVKLIGYSLGGGVAFEVAAKLVAAGRSVTFLGILDTNIGPGQHNYRERLARTAQRIRTHRVTVDR
MILRALAKLFAQFGAEAVLARGIDWLKWRSFARTRFILRLELEEVLRMRAFGQWLAQPKPTLPITATLFRCRRTGVPSDL
GWSAFVTGLNIIPIVGGHLDMLVEPYLGHNRPLIERAFVVSGE

Sequences:

>Translated_923_residues
MLETSGYPRLESRFPRALPSVGGPTTDQDVVMLRGNGPPDGFTWKQASARPLDMDGPTTRLFPRMGDGFSEKSAFSHLER
VVEKYPAKIAISDGSASLSFSELLNAVQNLAGAIAGSTPPGKAVGILIGNTLWYPVAMLAAMRAGRPAVPLNPRDPFQRL
AAISTSARLAAIIKPGPGKPAGWPNASSLEWIDAASCMAATPDGGLSALPSEVSVDAPAIVLYTSGSTGAPKGVVNSQRA
ILQRVQQYVDACHFGPDDVFMPLTGPATIAGCREMMTPMLCGATLYLSDIESAGIRAARDNFEKWRVTVVYLVPALLRVL
MNGSAPDTFSSLRIVRVGGEKILWSDIDRLRDSVHESCLVQISYSSTETTGTQWFLPRGYQERGATVPVGFVLPGIEYTI
VDENACEVAPGDEGELLIRSNYTTLGYWVDGENVPLQANSGNPMLRTFATGDLVKVDDTGMMWIVGRKGRQIKINGRRVE
PAELELVLRRAPQVDDAVAVVTDANELVAFVVPARPGASELIAELRDLIRTALPPAVHPTRLHSVAEIPRLKGGKVDGVK
LRELDRALNAQDAQNTPMARQAANPLDIEGTAAAVWERILPGKRTAGSRWDDAGGDSLKLLQFVMELETALGRELNLDAF
TVGMSFADVVRAASPGQDTSSSLVEASDPRPVLFIVPGSIGYGPSLAAFGAEMGKVARVVAIRYGDLNDLLRGHGTIPRM
VDAVVDQISQVQPDGDVKLIGYSLGGGVAFEVAAKLVAAGRSVTFLGILDTNIGPGQHNYRERLARTAQRIRTHRVTVDR
MILRALAKLFAQFGAEAVLARGIDWLKWRSFARTRFILRLELEEVLRMRAFGQWLAQPKPTLPITATLFRCRRTGVPSDL
GWSAFVTGLNIIPIVGGHLDMLVEPYLGHNRPLIERAFVVSGE
>Mature_923_residues
MLETSGYPRLESRFPRALPSVGGPTTDQDVVMLRGNGPPDGFTWKQASARPLDMDGPTTRLFPRMGDGFSEKSAFSHLER
VVEKYPAKIAISDGSASLSFSELLNAVQNLAGAIAGSTPPGKAVGILIGNTLWYPVAMLAAMRAGRPAVPLNPRDPFQRL
AAISTSARLAAIIKPGPGKPAGWPNASSLEWIDAASCMAATPDGGLSALPSEVSVDAPAIVLYTSGSTGAPKGVVNSQRA
ILQRVQQYVDACHFGPDDVFMPLTGPATIAGCREMMTPMLCGATLYLSDIESAGIRAARDNFEKWRVTVVYLVPALLRVL
MNGSAPDTFSSLRIVRVGGEKILWSDIDRLRDSVHESCLVQISYSSTETTGTQWFLPRGYQERGATVPVGFVLPGIEYTI
VDENACEVAPGDEGELLIRSNYTTLGYWVDGENVPLQANSGNPMLRTFATGDLVKVDDTGMMWIVGRKGRQIKINGRRVE
PAELELVLRRAPQVDDAVAVVTDANELVAFVVPARPGASELIAELRDLIRTALPPAVHPTRLHSVAEIPRLKGGKVDGVK
LRELDRALNAQDAQNTPMARQAANPLDIEGTAAAVWERILPGKRTAGSRWDDAGGDSLKLLQFVMELETALGRELNLDAF
TVGMSFADVVRAASPGQDTSSSLVEASDPRPVLFIVPGSIGYGPSLAAFGAEMGKVARVVAIRYGDLNDLLRGHGTIPRM
VDAVVDQISQVQPDGDVKLIGYSLGGGVAFEVAAKLVAAGRSVTFLGILDTNIGPGQHNYRERLARTAQRIRTHRVTVDR
MILRALAKLFAQFGAEAVLARGIDWLKWRSFARTRFILRLELEEVLRMRAFGQWLAQPKPTLPITATLFRCRRTGVPSDL
GWSAFVTGLNIIPIVGGHLDMLVEPYLGHNRPLIERAFVVSGE

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=537, Percent_Identity=27.1880819366853, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI187761343, Length=537, Percent_Identity=27.1880819366853, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI156151445, Length=563, Percent_Identity=23.9786856127886, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI38505220, Length=361, Percent_Identity=23.8227146814404, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI122937307, Length=375, Percent_Identity=25.0666666666667, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI28416953, Length=388, Percent_Identity=25.7731958762887, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI115511026, Length=384, Percent_Identity=23.1770833333333, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI8923896, Length=392, Percent_Identity=25.765306122449, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI253970489, Length=392, Percent_Identity=25.765306122449, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI42544132, Length=505, Percent_Identity=23.3663366336634, Blast_Score=73, Evalue=2e-12,
Organism=Escherichia coli, GI1786801, Length=737, Percent_Identity=26.0515603799186, Blast_Score=159, Evalue=9e-40,
Organism=Escherichia coli, GI1790505, Length=502, Percent_Identity=25.0996015936255, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI145693145, Length=527, Percent_Identity=24.8576850094877, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786810, Length=554, Percent_Identity=23.4657039711191, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788107, Length=549, Percent_Identity=23.6794171220401, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1789201, Length=372, Percent_Identity=28.2258064516129, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI221142682, Length=492, Percent_Identity=23.3739837398374, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531443, Length=353, Percent_Identity=27.4787535410765, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994703, Length=468, Percent_Identity=22.8632478632479, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994690, Length=468, Percent_Identity=22.8632478632479, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994694, Length=468, Percent_Identity=22.8632478632479, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17557194, Length=389, Percent_Identity=25.9640102827763, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538037, Length=398, Percent_Identity=24.6231155778894, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17556356, Length=373, Percent_Identity=24.3967828418231, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=547, Percent_Identity=24.1316270566728, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6319699, Length=346, Percent_Identity=25.4335260115607, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24648676, Length=582, Percent_Identity=25.2577319587629, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24667959, Length=392, Percent_Identity=23.9795918367347, Blast_Score=93, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24667955, Length=392, Percent_Identity=23.9795918367347, Blast_Score=93, Evalue=7e-19,
Organism=Drosophila melanogaster, GI62472339, Length=392, Percent_Identity=23.9795918367347, Blast_Score=93, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355181, Length=475, Percent_Identity=24.6315789473684, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859661, Length=413, Percent_Identity=25.90799031477, Blast_Score=83, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24648260, Length=380, Percent_Identity=26.0526315789474, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356947, Length=372, Percent_Identity=24.1935483870968, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356441, Length=428, Percent_Identity=23.3644859813084, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 99506; Mature: 99506

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLETSGYPRLESRFPRALPSVGGPTTDQDVVMLRGNGPPDGFTWKQASARPLDMDGPTTR
CCCCCCCCCHHHHCCHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHH
LFPRMGDGFSEKSAFSHLERVVEKYPAKIAISDGSASLSFSELLNAVQNLAGAIAGSTPP
HCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GKAVGILIGNTLWYPVAMLAAMRAGRPAVPLNPRDPFQRLAAISTSARLAAIIKPGPGKP
CCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCC
AGWPNASSLEWIDAASCMAATPDGGLSALPSEVSVDAPAIVLYTSGSTGAPKGVVNSQRA
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHH
ILQRVQQYVDACHFGPDDVFMPLTGPATIAGCREMMTPMLCGATLYLSDIESAGIRAARD
HHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCHHHEEHHHHHCCCHHHHC
NFEKWRVTVVYLVPALLRVLMNGSAPDTFSSLRIVRVGGEKILWSDIDRLRDSVHESCLV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEEECCCEEHHHHHHHHHHHHHHEEEE
QISYSSTETTGTQWFLPRGYQERGATVPVGFVLPGIEYTIVDENACEVAPGDEGELLIRS
EEEECCCCCCCCEEECCCCHHHCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCCEEEEE
NYTTLGYWVDGENVPLQANSGNPMLRTFATGDLVKVDDTGMMWIVGRKGRQIKINGRRVE
CCEEEEEEECCCCCEEEECCCCCEEEEECCCCEEEECCCCEEEEEECCCCEEEECCCCCC
PAELELVLRRAPQVDDAVAVVTDANELVAFVVPARPGASELIAELRDLIRTALPPAVHPT
HHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHH
RLHSVAEIPRLKGGKVDGVKLRELDRALNAQDAQNTPMARQAANPLDIEGTAAAVWERIL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHC
PGKRTAGSRWDDAGGDSLKLLQFVMELETALGRELNLDAFTVGMSFADVVRAASPGQDTS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCCCCC
SSLVEASDPRPVLFIVPGSIGYGPSLAAFGAEMGKVARVVAIRYGDLNDLLRGHGTIPRM
HHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEEEEEECCHHHHHHCCCCHHHH
VDAVVDQISQVQPDGDVKLIGYSLGGGVAFEVAAKLVAAGRSVTFLGILDTNIGPGQHNY
HHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHH
RERLARTAQRIRTHRVTVDRMILRALAKLFAQFGAEAVLARGIDWLKWRSFARTRFILRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHEEEEE
ELEEVLRMRAFGQWLAQPKPTLPITATLFRCRRTGVPSDLGWSAFVTGLNIIPIVGGHLD
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCHH
MLVEPYLGHNRPLIERAFVVSGE
HHHHHHCCCCCCHHHEEEEECCC
>Mature Secondary Structure
MLETSGYPRLESRFPRALPSVGGPTTDQDVVMLRGNGPPDGFTWKQASARPLDMDGPTTR
CCCCCCCCCHHHHCCHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHH
LFPRMGDGFSEKSAFSHLERVVEKYPAKIAISDGSASLSFSELLNAVQNLAGAIAGSTPP
HCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCC
GKAVGILIGNTLWYPVAMLAAMRAGRPAVPLNPRDPFQRLAAISTSARLAAIIKPGPGKP
CCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCC
AGWPNASSLEWIDAASCMAATPDGGLSALPSEVSVDAPAIVLYTSGSTGAPKGVVNSQRA
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHH
ILQRVQQYVDACHFGPDDVFMPLTGPATIAGCREMMTPMLCGATLYLSDIESAGIRAARD
HHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHCHHHEEHHHHHCCCHHHHC
NFEKWRVTVVYLVPALLRVLMNGSAPDTFSSLRIVRVGGEKILWSDIDRLRDSVHESCLV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEEECCCEEHHHHHHHHHHHHHHEEEE
QISYSSTETTGTQWFLPRGYQERGATVPVGFVLPGIEYTIVDENACEVAPGDEGELLIRS
EEEECCCCCCCCEEECCCCHHHCCCEEEEEEEECCEEEEEECCCCCCCCCCCCCCEEEEE
NYTTLGYWVDGENVPLQANSGNPMLRTFATGDLVKVDDTGMMWIVGRKGRQIKINGRRVE
CCEEEEEEECCCCCEEEECCCCCEEEEECCCCEEEECCCCEEEEEECCCCEEEECCCCCC
PAELELVLRRAPQVDDAVAVVTDANELVAFVVPARPGASELIAELRDLIRTALPPAVHPT
HHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHH
RLHSVAEIPRLKGGKVDGVKLRELDRALNAQDAQNTPMARQAANPLDIEGTAAAVWERIL
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHC
PGKRTAGSRWDDAGGDSLKLLQFVMELETALGRELNLDAFTVGMSFADVVRAASPGQDTS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCCCCCC
SSLVEASDPRPVLFIVPGSIGYGPSLAAFGAEMGKVARVVAIRYGDLNDLLRGHGTIPRM
HHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHEEEEEEEECCHHHHHHCCCCHHHH
VDAVVDQISQVQPDGDVKLIGYSLGGGVAFEVAAKLVAAGRSVTFLGILDTNIGPGQHNY
HHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHH
RERLARTAQRIRTHRVTVDRMILRALAKLFAQFGAEAVLARGIDWLKWRSFARTRFILRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHEEEEE
ELEEVLRMRAFGQWLAQPKPTLPITATLFRCRRTGVPSDLGWSAFVTGLNIIPIVGGHLD
CHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCHH
MLVEPYLGHNRPLIERAFVVSGE
HHHHHHCCCCCCHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]