Click here to switch to the map view.

The map label for this gene is afr [H]

Identifier: 13475546

GI number: 13475546

Start: 5441767

End: 5442834

Strand: Reverse

Name: afr [H]

Synonym: mll6645

Alternate gene names: 13475546

Gene position: 5442834-5441767 (Counterclockwise)

Preceding gene: 13475548

Following gene: 13475545

Centisome position: 77.36

GC content: 60.11

Gene sequence:

>1068_bases
ATGGGATGCGAAATTGATCGCGACGCAAGCGGGCTCCATAGTTTGCAAGGTTTAGCCGGGAGGGATGTTTCAGTGGCAGC
AGGCGCCAAGGTGGGTTGGTCCTTCATGGGGACCGGAACCATCGCTACGGAGCTGGTGGTCGAGGCAATCCGATCGGTCG
GCCATTCGCCGCTGTGGGTGGTGAGCAGAAGCAAGAGGGATGCCGACCATTTCGCCGAGGATCTTGGCATTCCGCATTCG
ACGACCGAGCTTGGACCTGTTCTGCAGGATCCATCGGTCGGGTTCGCCTATATCAGCGCCAGTCTCAAGCGCCGGCCGCA
CTACATCACCGCGGCAGCCGGTGCGGGCAAACATATTCTGTGCGACGGGCCGATTTCCTGCACCAGCAAGACGGCCAGCG
CATTGGTAGAGCTATGCCGGGGAGCGCGGGCGTCGCTGGTGGTCAATCAGCGCTTGCGGGCATCGACTATCCATCAAACG
ATGCGGCGGTTGGTACGGGATGGCGACATCGGCGCGGTTCAATCGATCGTGTTGATACGTGGAGGACCCTATCAGGCCCC
GCCCAACCGAAGCGCCCGGGACTTCAACGATGGTAGCGGAATTTACCTCGACGTCTCCGTCGAGAACATCGACCTGGCGC
GTTTCCTGACCGGTGCGGAACCGGTAGAGGCCACTGCTCTGATCACATCGGAAAAAATGGTGCCGAGCCAAGCGACCTAT
ATACTCCGGCTCAGCGATGGAAGCCTTTTTCAGGCCCATGAAAGCTTCAGGACCGCCGACATCGAAAGCATGGTGCTCGT
GGCGGGCGATAGAGGTGCCCTGATTGCGCAAGGCACGCTGAATGGCCGCACGTCGGGGACGCTGATGCGACGAGCAGATG
GCAGGAACGAAGCTGTCCCCGTTCGCGACCACGATGTCCACCTAGCAACCGTTAGAGAATTTGCCAATACGCGCGGCCAA
ACGCCGTCCTGGTTATCGCAGGGCACTGACAGTGTTATTGCCCTGCGAACTGTCGAAGCCGTCGCCATGTCCGCGAAAAA
GCGCCGTACGGTTCCCATTCAAGGCTAG

Upstream 100 bases:

>100_bases
CAACGCGCCAGTGTTCTCGCCAATATACGTCACCGCAGGCTTCTCCAGCAAATATGAAGCAACTAGACGCTACGACTACG
CCGAAGTGAGAAGGACTTCA

Downstream 100 bases:

>100_bases
CGCCATCCAATCCAACGATGCTGCCCTCGGCAGGGAGTCATGATGAAAAGCAATCCCATCCTGTTCCACTCGCTTGCCGC
CCGGCATTCCACGCTCGCCA

Product: putative oxidoreductase

Products: NA

Alternate protein names: Anhydrofructose reductase; 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MGCEIDRDASGLHSLQGLAGRDVSVAAGAKVGWSFMGTGTIATELVVEAIRSVGHSPLWVVSRSKRDADHFAEDLGIPHS
TTELGPVLQDPSVGFAYISASLKRRPHYITAAAGAGKHILCDGPISCTSKTASALVELCRGARASLVVNQRLRASTIHQT
MRRLVRDGDIGAVQSIVLIRGGPYQAPPNRSARDFNDGSGIYLDVSVENIDLARFLTGAEPVEATALITSEKMVPSQATY
ILRLSDGSLFQAHESFRTADIESMVLVAGDRGALIAQGTLNGRTSGTLMRRADGRNEAVPVRDHDVHLATVREFANTRGQ
TPSWLSQGTDSVIALRTVEAVAMSAKKRRTVPIQG

Sequences:

>Translated_355_residues
MGCEIDRDASGLHSLQGLAGRDVSVAAGAKVGWSFMGTGTIATELVVEAIRSVGHSPLWVVSRSKRDADHFAEDLGIPHS
TTELGPVLQDPSVGFAYISASLKRRPHYITAAAGAGKHILCDGPISCTSKTASALVELCRGARASLVVNQRLRASTIHQT
MRRLVRDGDIGAVQSIVLIRGGPYQAPPNRSARDFNDGSGIYLDVSVENIDLARFLTGAEPVEATALITSEKMVPSQATY
ILRLSDGSLFQAHESFRTADIESMVLVAGDRGALIAQGTLNGRTSGTLMRRADGRNEAVPVRDHDVHLATVREFANTRGQ
TPSWLSQGTDSVIALRTVEAVAMSAKKRRTVPIQG
>Mature_354_residues
GCEIDRDASGLHSLQGLAGRDVSVAAGAKVGWSFMGTGTIATELVVEAIRSVGHSPLWVVSRSKRDADHFAEDLGIPHST
TELGPVLQDPSVGFAYISASLKRRPHYITAAAGAGKHILCDGPISCTSKTASALVELCRGARASLVVNQRLRASTIHQTM
RRLVRDGDIGAVQSIVLIRGGPYQAPPNRSARDFNDGSGIYLDVSVENIDLARFLTGAEPVEATALITSEKMVPSQATYI
LRLSDGSLFQAHESFRTADIESMVLVAGDRGALIAQGTLNGRTSGTLMRRADGRNEAVPVRDHDVHLATVREFANTRGQT
PSWLSQGTDSVIALRTVEAVAMSAKKRRTVPIQG

Specific function: Catalyzes the NADPH-specific reduction of 1,5-anhydro-D- fructose to 1,5-anhydro-D-mannitol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.292 [H]

Molecular weight: Translated: 37831; Mature: 37700

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGCEIDRDASGLHSLQGLAGRDVSVAAGAKVGWSFMGTGTIATELVVEAIRSVGHSPLWV
CCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEE
VSRSKRDADHFAEDLGIPHSTTELGPVLQDPSVGFAYISASLKRRPHYITAAAGAGKHIL
EECCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHEEHHHHCCCCEEEEECCCCCEEE
CDGPISCTSKTASALVELCRGARASLVVNQRLRASTIHQTMRRLVRDGDIGAVQSIVLIR
ECCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
GGPYQAPPNRSARDFNDGSGIYLDVSVENIDLARFLTGAEPVEATALITSEKMVPSQATY
CCCCCCCCCCCCCCCCCCCCEEEEEEECCEEHHHHHCCCCCCCEEEEEECCCCCCCCCEE
ILRLSDGSLFQAHESFRTADIESMVLVAGDRGALIAQGTLNGRTSGTLMRRADGRNEAVP
EEEECCCCEEHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCC
VRDHDVHLATVREFANTRGQTPSWLSQGTDSVIALRTVEAVAMSAKKRRTVPIQG
CCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GCEIDRDASGLHSLQGLAGRDVSVAAGAKVGWSFMGTGTIATELVVEAIRSVGHSPLWV
CCCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEE
VSRSKRDADHFAEDLGIPHSTTELGPVLQDPSVGFAYISASLKRRPHYITAAAGAGKHIL
EECCCCCHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHEEHHHHCCCCEEEEECCCCCEEE
CDGPISCTSKTASALVELCRGARASLVVNQRLRASTIHQTMRRLVRDGDIGAVQSIVLIR
ECCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
GGPYQAPPNRSARDFNDGSGIYLDVSVENIDLARFLTGAEPVEATALITSEKMVPSQATY
CCCCCCCCCCCCCCCCCCCCEEEEEEECCEEHHHHHCCCCCCCEEEEEECCCCCCCCCEE
ILRLSDGSLFQAHESFRTADIESMVLVAGDRGALIAQGTLNGRTSGTLMRRADGRNEAVP
EEEECCCCEEHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCC
VRDHDVHLATVREFANTRGQTPSWLSQGTDSVIALRTVEAVAMSAKKRRTVPIQG
CCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]