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The map label for this gene is hisN [H]

Identifier: 13475544

GI number: 13475544

Start: 5440080

End: 5440799

Strand: Reverse

Name: hisN [H]

Synonym: mll6642

Alternate gene names: 13475544

Gene position: 5440799-5440080 (Counterclockwise)

Preceding gene: 13475545

Following gene: 13475542

Centisome position: 77.33

GC content: 60.69

Gene sequence:

>720_bases
ATGCACAATCTGCCAGACATCTCCTTCTTCCATCGGCTTGCGGATGCAGCCGCGAACGTTGCCCTGGCCTACTATCGCAA
GCCGATCGAGGTCGAGGAGAAGGTGAAACCGGGTTATCGCTTCGACCCGGTGACGATTGCCGACAAGAAGGCGGAACAGG
TCATCCGCGCGCTGATCTCGGGAGAATTCCCGGACCATGCGGTGCTTGGCGAGGAGTTTGGCGAAAGCGGCCAGGGACCC
GTCAAATGGATCATCGACCCGATCGACGGCACCCGGCCATTCATCTGCGGCATTCCCGTCTGGGGCACCCTTATCGGCCT
GACGGTCGATGGAAAGGCCTGCATGGGCATGATGAGCCAGCCCTTTACCGGCGAACGGTTTTGGGCCACCGGGACCGAGG
CGTGGACAGGTGGCGCATCAGGCTCGAGCCGGCTGCAGACGAAGGCTGCGGGCTCGTTGGCCACCGCGATCCTTCATACC
AATTCACCCGACAGGTTTCCGGATTTCCCCGACATCAACTTCGCCCGTCTTAAGGATGCCGCGCTGATGACCCGCTACGG
CGGCGAGTGCTATGCCTTCGCGATGCTGGCGGCCGGGCAGATCGTCTGTGACGACTCGGACATCCAATGCCGAGTTTGTT
CGGCCGGCGAGCGAACTTGGCTCTCTCTAATGCGACCTGACAATCGCCACTGCTATTGTCTCAGCAGCCACAATAAATGA

Upstream 100 bases:

>100_bases
CTATGACGTGGCCCGCAGCCTCAACGCGCTGATGCGGGACCTTGTCGGCGCCTGACGACCTCATCCCCAGCTACCTGCCC
CAACCGACAAGTGGAACGCC

Downstream 100 bases:

>100_bases
GCGCATTGAGTTGGCAGAGGGAATTTTCGGCAAGCTCGGGCCATCCACAACGCCCAGATGTTCAGTCCCGTCGGCGCGCA
TGGCCAGGCCCCGACGATCA

Product: N-amidino-scyllo-inosamine-4-phosphate phosphatase

Products: NA

Alternate protein names: HolPase; Histidinol-phosphate phosphatase [H]

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MHNLPDISFFHRLADAAANVALAYYRKPIEVEEKVKPGYRFDPVTIADKKAEQVIRALISGEFPDHAVLGEEFGESGQGP
VKWIIDPIDGTRPFICGIPVWGTLIGLTVDGKACMGMMSQPFTGERFWATGTEAWTGGASGSSRLQTKAAGSLATAILHT
NSPDRFPDFPDINFARLKDAALMTRYGGECYAFAMLAAGQIVCDDSDIQCRVCSAGERTWLSLMRPDNRHCYCLSSHNK

Sequences:

>Translated_239_residues
MHNLPDISFFHRLADAAANVALAYYRKPIEVEEKVKPGYRFDPVTIADKKAEQVIRALISGEFPDHAVLGEEFGESGQGP
VKWIIDPIDGTRPFICGIPVWGTLIGLTVDGKACMGMMSQPFTGERFWATGTEAWTGGASGSSRLQTKAAGSLATAILHT
NSPDRFPDFPDINFARLKDAALMTRYGGECYAFAMLAAGQIVCDDSDIQCRVCSAGERTWLSLMRPDNRHCYCLSSHNK
>Mature_239_residues
MHNLPDISFFHRLADAAANVALAYYRKPIEVEEKVKPGYRFDPVTIADKKAEQVIRALISGEFPDHAVLGEEFGESGQGP
VKWIIDPIDGTRPFICGIPVWGTLIGLTVDGKACMGMMSQPFTGERFWATGTEAWTGGASGSSRLQTKAAGSLATAILHT
NSPDRFPDFPDINFARLKDAALMTRYGGECYAFAMLAAGQIVCDDSDIQCRVCSAGERTWLSLMRPDNRHCYCLSSHNK

Specific function: Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788882, Length=207, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011809
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 26168; Mature: 26168

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNLPDISFFHRLADAAANVALAYYRKPIEVEEKVKPGYRFDPVTIADKKAEQVIRALIS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEECCHHHHHHHHHHHC
GEFPDHAVLGEEFGESGQGPVKWIIDPIDGTRPFICGIPVWGTLIGLTVDGKACMGMMSQ
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCHHHEEEEEEECCHHHHHHHCC
PFTGERFWATGTEAWTGGASGSSRLQTKAAGSLATAILHTNSPDRFPDFPDINFARLKDA
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHH
ALMTRYGGECYAFAMLAAGQIVCDDSDIQCRVCSAGERTWLSLMRPDNRHCYCLSSHNK
HHHHHCCCCCEEEHHHHCCEEEECCCCCEEEEECCCCCEEHEEECCCCCEEEEECCCCC
>Mature Secondary Structure
MHNLPDISFFHRLADAAANVALAYYRKPIEVEEKVKPGYRFDPVTIADKKAEQVIRALIS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEECCHHHHHHHHHHHC
GEFPDHAVLGEEFGESGQGPVKWIIDPIDGTRPFICGIPVWGTLIGLTVDGKACMGMMSQ
CCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEECCCHHHEEEEEEECCHHHHHHHCC
PFTGERFWATGTEAWTGGASGSSRLQTKAAGSLATAILHTNSPDRFPDFPDINFARLKDA
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCCCHHHHHHH
ALMTRYGGECYAFAMLAAGQIVCDDSDIQCRVCSAGERTWLSLMRPDNRHCYCLSSHNK
HHHHHCCCCCEEEHHHHCCEEEECCCCCEEEEECCCCCEEHEEECCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626508 [H]