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The map label for this gene is acoR [H]

Identifier: 13475542

GI number: 13475542

Start: 5437867

End: 5438829

Strand: Reverse

Name: acoR [H]

Synonym: mll6640

Alternate gene names: 13475542

Gene position: 5438829-5437867 (Counterclockwise)

Preceding gene: 13475544

Following gene: 13475541

Centisome position: 77.3

GC content: 64.07

Gene sequence:

>963_bases
ATGGGCGGGGACCTATTCGGTCATCACGCTGACCGCATTCAGGCCGCGATCGCATCAGATGCGGCGGCGAAGTCCGCGCT
GGTCGCATCTTGGCGACGGTCTTGCAATTTGCATCGGCTCGATCCAGCCGACCGCAGTCCACCACGCTACCTCACGGAGA
CGGAACTGGGGCGGGCCCGACAACGCATCGAACCACTCGTCCGGGCCGCCCAATCGAGTCTGGACCGGCTCTATCTTGCG
GTGGGCGGCGTTGGGTGCTGTGTCCTCCTCGCCGATCGTGACGGCGTGCCGGTCGAACGGCGCGGCGCGCCTGTGGATGA
CGAGACTTTTCATTCCTGGGGCTTGTGGACTGGCTCCGTGTGGAACGAACAAAGCGAGGGCACCAACGGTATCGGCACCT
GTCTGGTCGAACAGCGCGCGCTGACGATCCACCGCGACCAGCATTTCCACACGCGCAATACGGGCCTCAGCTGCACCACG
GCTCCTATCTACGATCACCAGGGAGATCTTGTGGCCGCGCTTGACGTTTCTTCCTGCCGCGCTGACCTGACCGAAGCTTT
TGCCAACCTTATTTCTTTGGCCGTTGTCGACGCGGCGCGTCGGATCGAGGCAGAGAACTTCAAAATGGCATTCCCCAAGG
CGCGCATTCTGCTGGCCCCGGTGGCCGACAAAGGCTCCGGTGCACTGATCGCCGTAGATAGCGACGACCTGGTGGTCGGC
GCGACTCGACAGGCTCGCATCGCGCTTGGAATCACCCAGCAGTGTCTCGACAAGCCGATGCCAGCGGCCGATCTGCTTGG
CTGGACTGGCCCCGAAATCCTCGCCGAGGCTGAGCGCGGTGTTTTACAACGGGCGCTGGCCCGGGCGGACGGAAATGTCT
CGGCGGCGGCTCAGGCGCTTGGCATCAGCCGCGCGACGCTGCACCGCAAGCTCAACCGCCTGGACGCTCACAAGTCGCAC
TGA

Upstream 100 bases:

>100_bases
CAGTGTGATGATTGAGAGCGGAAAAGCAGGCGCGATGGCAGCGTAGGCTTGTCGTGCAGCTGACTTGGTGCGGGAGAAGA
GTCGGGATTGGGAGGATAGC

Downstream 100 bases:

>100_bases
CCATTCGGAACCTCACACGACTGTCGCAATTGTGCGACACATCTGGCCCGCCAGCTGTTTCCGGGGCGATGACATTGGCA
GCATAAATCGCAAGTCTCTT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MGGDLFGHHADRIQAAIASDAAAKSALVASWRRSCNLHRLDPADRSPPRYLTETELGRARQRIEPLVRAAQSSLDRLYLA
VGGVGCCVLLADRDGVPVERRGAPVDDETFHSWGLWTGSVWNEQSEGTNGIGTCLVEQRALTIHRDQHFHTRNTGLSCTT
APIYDHQGDLVAALDVSSCRADLTEAFANLISLAVVDAARRIEAENFKMAFPKARILLAPVADKGSGALIAVDSDDLVVG
ATRQARIALGITQQCLDKPMPAADLLGWTGPEILAEAERGVLQRALARADGNVSAAAQALGISRATLHRKLNRLDAHKSH

Sequences:

>Translated_320_residues
MGGDLFGHHADRIQAAIASDAAAKSALVASWRRSCNLHRLDPADRSPPRYLTETELGRARQRIEPLVRAAQSSLDRLYLA
VGGVGCCVLLADRDGVPVERRGAPVDDETFHSWGLWTGSVWNEQSEGTNGIGTCLVEQRALTIHRDQHFHTRNTGLSCTT
APIYDHQGDLVAALDVSSCRADLTEAFANLISLAVVDAARRIEAENFKMAFPKARILLAPVADKGSGALIAVDSDDLVVG
ATRQARIALGITQQCLDKPMPAADLLGWTGPEILAEAERGVLQRALARADGNVSAAAQALGISRATLHRKLNRLDAHKSH
>Mature_319_residues
GGDLFGHHADRIQAAIASDAAAKSALVASWRRSCNLHRLDPADRSPPRYLTETELGRARQRIEPLVRAAQSSLDRLYLAV
GGVGCCVLLADRDGVPVERRGAPVDDETFHSWGLWTGSVWNEQSEGTNGIGTCLVEQRALTIHRDQHFHTRNTGLSCTTA
PIYDHQGDLVAALDVSSCRADLTEAFANLISLAVVDAARRIEAENFKMAFPKARILLAPVADKGSGALIAVDSDDLVVGA
TRQARIALGITQQCLDKPMPAADLLGWTGPEILAEAERGVLQRALARADGNVSAAAQALGISRATLHRKLNRLDAHKSH

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 34380; Mature: 34249

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGDLFGHHADRIQAAIASDAAAKSALVASWRRSCNLHRLDPADRSPPRYLTETELGRAR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHH
QRIEPLVRAAQSSLDRLYLAVGGVGCCVLLADRDGVPVERRGAPVDDETFHSWGLWTGSV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCCCCCCCCHHCCCEECCC
WNEQSEGTNGIGTCLVEQRALTIHRDQHFHTRNTGLSCTTAPIYDHQGDLVAALDVSSCR
CCCCCCCCCCHHHHHHHHHHHEEECCCCCEECCCCCEEEECCCCCCCCCEEEEEEHHHHH
ADLTEAFANLISLAVVDAARRIEAENFKMAFPKARILLAPVADKGSGALIAVDSDDLVVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCEEEEECCCCEEEE
ATRQARIALGITQQCLDKPMPAADLLGWTGPEILAEAERGVLQRALARADGNVSAAAQAL
CCCCEEEEECCHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GISRATLHRKLNRLDAHKSH
CCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GGDLFGHHADRIQAAIASDAAAKSALVASWRRSCNLHRLDPADRSPPRYLTETELGRAR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHH
QRIEPLVRAAQSSLDRLYLAVGGVGCCVLLADRDGVPVERRGAPVDDETFHSWGLWTGSV
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCCCCCCCCHHCCCEECCC
WNEQSEGTNGIGTCLVEQRALTIHRDQHFHTRNTGLSCTTAPIYDHQGDLVAALDVSSCR
CCCCCCCCCCHHHHHHHHHHHEEECCCCCEECCCCCEEEECCCCCCCCCEEEEEEHHHHH
ADLTEAFANLISLAVVDAARRIEAENFKMAFPKARILLAPVADKGSGALIAVDSDDLVVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCCCEEEEECCCCEEEE
ATRQARIALGITQQCLDKPMPAADLLGWTGPEILAEAERGVLQRALARADGNVSAAAQAL
CCCCEEEEECCHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GISRATLHRKLNRLDAHKSH
CCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]