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The map label for this gene is appC [H]

Identifier: 13475078

GI number: 13475078

Start: 4921368

End: 4922300

Strand: Direct

Name: appC [H]

Synonym: mlr6084

Alternate gene names: 13475078

Gene position: 4921368-4922300 (Clockwise)

Preceding gene: 13475077

Following gene: 13475079

Centisome position: 69.94

GC content: 59.81

Gene sequence:

>933_bases
ATGAGCGAAAGTACAGTTCGACCTTCCCCGCGAGGCCGGGCGCGAGCGATAAAAGACTTTCTGCGTCAATTTCTTGGCCA
CGGCGGGGCTCAGGCGGGCGTCGTATGTCTGGTCTTCTTTCTTGTGCTGGCTGCCGCCCCAAATACCCTTGTGGGACCGC
TCCAGACTGCAATCAACGCAACGGGCGATTTCCTCGCGCCACCATCAAGCCAGCATCTGCTAGGGACCGACGAGGTGGGG
CGGGACGTGCTCAATATGGTCGTCCATGGTGCCCGGATCTCGCTTACGATCGCGCTGCTGGCGACCGTGATCAGCCTCGT
CGTCGGCACTGCGGTTGGTATCACCGCTGGCTACTACGGTGGCAGGGTTGACGTCTGGCTGATGCGCCTGACGGATTTCT
TTTTTGTCATGCCGTCCTTCGTGCTGGCACTGGTCATCACCCCTGTGGTTCTCGAGGTGATGGGGCGCGGGGGAGACATC
CTCGGCTTTCGTCCTTCTCTTTTTGTGATCCTTGTCGTTATCGGCATGACAAGCTGGGCGTTCGTCGCGCGCATCGTTCG
CAGTCAGACACTGTCGCTTAAGGAGCGAACATTCATTGATCGTGCGCGCGTTGTGGGCAGCAGCAATTTCAGCATCATGG
TGCGGCATATTCTTCCCAATCTCGTGCCGCAAATCGCTGCCAATGGTGCCCTGGTCGTCGCCGGAGCAATCTATGTCGAG
ACGTCGCTCTCGTTCCTCGGGCTTGGCGATCCGTTGCAGCCTTCATGGGGCACTTTGCTGTCGCTCGCTCAACGCGCTGG
AGCCGCTAGCGCCGGAGCGTGGTGGTACCTCGGTGCCCCCGGAGTGTGCGTGCTTTCGGTTTCCCTTAGCTTCGTCCTGA
TTGGCAACGCCCTCGACGACACGTTCAACCCACGGCGGAGGGTTATTCCATGA

Upstream 100 bases:

>100_bases
CTATCCTTCAAGGCATTTTCCTGTTGCTTGGTGCGTCGATCGTTGTTGCAAACCTCGTAGCTGATCTCGCCTATGGCCTT
CTTGATCCGCGAGTCCGCCA

Downstream 100 bases:

>100_bases
CAAACTCCTCTCGAGACAAGCCGTCGGTTTTGGAAGTCGACGGTCTCGCTGTCGACTATGGGCTCAAGGGCGTTTCATTG
CGAGCGATCGACAATGTGAC

Product: ABC transporter, permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSESTVRPSPRGRARAIKDFLRQFLGHGGAQAGVVCLVFFLVLAAAPNTLVGPLQTAINATGDFLAPPSSQHLLGTDEVG
RDVLNMVVHGARISLTIALLATVISLVVGTAVGITAGYYGGRVDVWLMRLTDFFFVMPSFVLALVITPVVLEVMGRGGDI
LGFRPSLFVILVVIGMTSWAFVARIVRSQTLSLKERTFIDRARVVGSSNFSIMVRHILPNLVPQIAANGALVVAGAIYVE
TSLSFLGLGDPLQPSWGTLLSLAQRAGAASAGAWWYLGAPGVCVLSVSLSFVLIGNALDDTFNPRRRVIP

Sequences:

>Translated_310_residues
MSESTVRPSPRGRARAIKDFLRQFLGHGGAQAGVVCLVFFLVLAAAPNTLVGPLQTAINATGDFLAPPSSQHLLGTDEVG
RDVLNMVVHGARISLTIALLATVISLVVGTAVGITAGYYGGRVDVWLMRLTDFFFVMPSFVLALVITPVVLEVMGRGGDI
LGFRPSLFVILVVIGMTSWAFVARIVRSQTLSLKERTFIDRARVVGSSNFSIMVRHILPNLVPQIAANGALVVAGAIYVE
TSLSFLGLGDPLQPSWGTLLSLAQRAGAASAGAWWYLGAPGVCVLSVSLSFVLIGNALDDTFNPRRRVIP
>Mature_309_residues
SESTVRPSPRGRARAIKDFLRQFLGHGGAQAGVVCLVFFLVLAAAPNTLVGPLQTAINATGDFLAPPSSQHLLGTDEVGR
DVLNMVVHGARISLTIALLATVISLVVGTAVGITAGYYGGRVDVWLMRLTDFFFVMPSFVLALVITPVVLEVMGRGGDIL
GFRPSLFVILVVIGMTSWAFVARIVRSQTLSLKERTFIDRARVVGSSNFSIMVRHILPNLVPQIAANGALVVAGAIYVET
SLSFLGLGDPLQPSWGTLLSLAQRAGAASAGAWWYLGAPGVCVLSVSLSFVLIGNALDDTFNPRRRVIP

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=290, Percent_Identity=31.7241379310345, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787760, Length=309, Percent_Identity=29.4498381877023, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787498, Length=299, Percent_Identity=38.1270903010033, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788505, Length=257, Percent_Identity=32.6848249027237, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789964, Length=298, Percent_Identity=32.8859060402685, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=29.6296296296296, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787549, Length=206, Percent_Identity=26.2135922330097, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32911; Mature: 32780

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESTVRPSPRGRARAIKDFLRQFLGHGGAQAGVVCLVFFLVLAAAPNTLVGPLQTAINA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
TGDFLAPPSSQHLLGTDEVGRDVLNMVVHGARISLTIALLATVISLVVGTAVGITAGYYG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRVDVWLMRLTDFFFVMPSFVLALVITPVVLEVMGRGGDILGFRPSLFVILVVIGMTSWA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHH
FVARIVRSQTLSLKERTFIDRARVVGSSNFSIMVRHILPNLVPQIAANGALVVAGAIYVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
TSLSFLGLGDPLQPSWGTLLSLAQRAGAASAGAWWYLGAPGVCVLSVSLSFVLIGNALDD
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHEECCHHCC
TFNPRRRVIP
CCCCCCCCCC
>Mature Secondary Structure 
SESTVRPSPRGRARAIKDFLRQFLGHGGAQAGVVCLVFFLVLAAAPNTLVGPLQTAINA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
TGDFLAPPSSQHLLGTDEVGRDVLNMVVHGARISLTIALLATVISLVVGTAVGITAGYYG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRVDVWLMRLTDFFFVMPSFVLALVITPVVLEVMGRGGDILGFRPSLFVILVVIGMTSWA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHH
FVARIVRSQTLSLKERTFIDRARVVGSSNFSIMVRHILPNLVPQIAANGALVVAGAIYVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
TSLSFLGLGDPLQPSWGTLLSLAQRAGAASAGAWWYLGAPGVCVLSVSLSFVLIGNALDD
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHEECCHHCC
TFNPRRRVIP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]