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The map label for this gene is bioD [H]

Identifier: 13475017

GI number: 13475017

Start: 4854824

End: 4855459

Strand: Reverse

Name: bioD [H]

Synonym: mll6005

Alternate gene names: 13475017

Gene position: 4855459-4854824 (Counterclockwise)

Preceding gene: 13475018

Following gene: 13475016

Centisome position: 69.01

GC content: 62.11

Gene sequence:

>636_bases
ATGACCAAGCGCATCGTCATCACCGGAACAGATACCGGAATCGGCAAGACGGTGTTTTCGGCGGGATTGGCCGGCTTCCT
CAACGGCTTCTACTGGAAGCCGGTGCAGTCGGGCCTCGACGGCGAGACCGACAGCGAGGTTGTTGCGCGGCTTGCCGGCC
TTCCGCCGGGGCGCGTGCTGCCGGAAGTGTATCGCCTGAAGGAGCCGCTGTCGCCGCATCGTTCGGCCGAAATCGACGGC
ATCGCGATCGAGGCGGCCAAGCTATCACTTCCAGACTTGCCGGGCCCGCTCATCATCGAAGGCGCCGGCGGGCTGATGGT
GCCGCTCAATCGACAGACAAAGTTCATCGATATTTTCCGGGAATGGCAACTGCCGGTCATTCTTTGCGCACGCACCGCGC
TCGGCACCATCAACCACACCCTGCTGTCGATCGAGGTCCTGCGGGCCCGCTCCATCCCCCTGATCGGCGTTGCCTTCATT
GGTGATGAGGTAGCCGACACACAAAGGACAATCGTCGAATTCAGCGGCGTGCCGCAGCTTGGCAGGCTGCCGCACCTCGA
TCCGCTGATGGGTGGAACGCTGAGAGATGCAATGATTGCCGGATTCGACCTTGCCCTTACTGCCGGAGGCGAATGA

Upstream 100 bases:

>100_bases
CCGAGGGCACATCGCGACTGCGCATTTCGCTGACGCTCAACGTCGACGAAGCCGACATTTCGGCCATGCTCGAGGCGCTC
GTCGAGGTGCTGGCCTCGAC

Downstream 100 bases:

>100_bases
TGACGCAGTCTCGAGTCTGGCATCCGTTCACCCAGCACGCGCTTGAGCCCGCGATCCCTGAAATCGTGCTGACGGAAGGC
GCCTATCTCCACAAGACCGA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTKRIVITGTDTGIGKTVFSAGLAGFLNGFYWKPVQSGLDGETDSEVVARLAGLPPGRVLPEVYRLKEPLSPHRSAEIDG
IAIEAAKLSLPDLPGPLIIEGAGGLMVPLNRQTKFIDIFREWQLPVILCARTALGTINHTLLSIEVLRARSIPLIGVAFI
GDEVADTQRTIVEFSGVPQLGRLPHLDPLMGGTLRDAMIAGFDLALTAGGE

Sequences:

>Translated_211_residues
MTKRIVITGTDTGIGKTVFSAGLAGFLNGFYWKPVQSGLDGETDSEVVARLAGLPPGRVLPEVYRLKEPLSPHRSAEIDG
IAIEAAKLSLPDLPGPLIIEGAGGLMVPLNRQTKFIDIFREWQLPVILCARTALGTINHTLLSIEVLRARSIPLIGVAFI
GDEVADTQRTIVEFSGVPQLGRLPHLDPLMGGTLRDAMIAGFDLALTAGGE
>Mature_210_residues
TKRIVITGTDTGIGKTVFSAGLAGFLNGFYWKPVQSGLDGETDSEVVARLAGLPPGRVLPEVYRLKEPLSPHRSAEIDGI
AIEAAKLSLPDLPGPLIIEGAGGLMVPLNRQTKFIDIFREWQLPVILCARTALGTINHTLLSIEVLRARSIPLIGVAFIG
DEVADTQRTIVEFSGVPQLGRLPHLDPLMGGTLRDAMIAGFDLALTAGGE

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=210, Percent_Identity=32.3809523809524, Blast_Score=88, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324385, Length=156, Percent_Identity=34.6153846153846, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 22487; Mature: 22355

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRIVITGTDTGIGKTVFSAGLAGFLNGFYWKPVQSGLDGETDSEVVARLAGLPPGRVL
CCCEEEEEECCCCCHHHHHHHHHHHHHCCEECCHHHCCCCCCCHHHHHHHHHCCCCCCHH
PEVYRLKEPLSPHRSAEIDGIAIEAAKLSLPDLPGPLIIEGAGGLMVPLNRQTKFIDIFR
HHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCHHHHHHH
EWQLPVILCARTALGTINHTLLSIEVLRARSIPLIGVAFIGDEVADTQRTIVEFSGVPQL
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHEECCCCCC
GRLPHLDPLMGGTLRDAMIAGFDLALTAGGE
CCCCCCCCCCCCHHHHHHHHCCEEEEECCCC
>Mature Secondary Structure 
TKRIVITGTDTGIGKTVFSAGLAGFLNGFYWKPVQSGLDGETDSEVVARLAGLPPGRVL
CCEEEEEECCCCCHHHHHHHHHHHHHCCEECCHHHCCCCCCCHHHHHHHHHCCCCCCHH
PEVYRLKEPLSPHRSAEIDGIAIEAAKLSLPDLPGPLIIEGAGGLMVPLNRQTKFIDIFR
HHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCHHHHHHH
EWQLPVILCARTALGTINHTLLSIEVLRARSIPLIGVAFIGDEVADTQRTIVEFSGVPQL
HCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHEECCCCCC
GRLPHLDPLMGGTLRDAMIAGFDLALTAGGE
CCCCCCCCCCCCHHHHHHHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA