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The map label for this gene is nadA1

Identifier: 13474859

GI number: 13474859

Start: 4707767

End: 4708741

Strand: Reverse

Name: nadA1

Synonym: mll5835

Alternate gene names: 13474859

Gene position: 4708741-4707767 (Counterclockwise)

Preceding gene: 13474860

Following gene: 13474858

Centisome position: 66.92

GC content: 62.26

Gene sequence:

>975_bases
ATGAGTGCCGTCCTGCCTTCGAGCGCCTCACTGTACGACCGCGTTCGGCGCGTTATCCCACCGATCGAGTGGTCGGTCTT
CGTCGAGGATATCGACGCAATCCTGAATCTGAAGCGACAGCGCAATGCGGTCATCCTGGCGCATAACTACCAGACGCCGG
AGATTTTTCACTGCGTGGCTGACATCGTCGGCGACAGCCTGGCGCTGGCCCGCAAGGCGATGACAGTCGATGCCGAAATC
ATCGTGCTCGCGGGCGTGCATTTTATGGCCGAGACCGCCAAGCTCCTCAATCCGGACAAGACCGTGCTCATCCCGGATCT
CGGCGCCGGCTGTTCGCTGGCCGAGTCGATCACCGCCGAAGACGTGCGCCTGATGCGGCAGCGTTATCCGAGCGTTCCAG
TGGTGACCTACGTCAACACCTCCGCCGCGGTGAAGGCTGAATCCGACATCTGCTGCACCTCGGGCAATGCGCTCGCGGTG
GTGAAATCGCTCGGTGCGCCGCGTGTGATCATGCTGCCCGATGAATATCTGGCGAAGAACATCGCGGCGCAGACCAAGGT
CGAGATCATTGCCTGGAAGGGGCGCTGCGAGGTGCACGAACGCTTCACCGCGGCCGACATCCGCGAGCTGCGTGAGGCCC
ATCCCGGCATCAGTGTACTTGCCCATCCCGAATGTCCGCCTGAAGTGGTCGCGGAAGCCGACTTCGCCGGCTCGACGGCG
GCGATGTCCGACTATGTCGCGCGGCATAGGCCGGCGCGTGTGGTGCTGATGACGGAATGTTCCATGAGCGACAACGTCGC
GGTCGAGCATCCGGAAGTAGATTTCGTGCGCCCATGCAATCTGTGCCCGCATATGAAGCGCATCACGCTCGCCAACATCC
GGACCGCGCTCGAGGAGAACCGCCACGTCGTCACGATCGATCCTCATGTCGCTGAACGGGCCCGCTGGGCTGTGGAACGC
ATGCTCTTTGTATGA

Upstream 100 bases:

>100_bases
GTGGCCGGCACAAAATTACCGCTCGCACGGGCTTGACACCCCTTATAGTCACAACGATTATATATATCTTATAATCAGAT
GGACTATAACTGGAGGCTCG

Downstream 100 bases:

>100_bases
CGGCGGACATCCATCACATTGGCGGAGCGCCGGTCATTATCGGCGCTGGTATCGCCGGGCTCATGACGGCGCTACACTTG
GCGCCGCAACCAGTCGTCCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSAVLPSSASLYDRVRRVIPPIEWSVFVEDIDAILNLKRQRNAVILAHNYQTPEIFHCVADIVGDSLALARKAMTVDAEI
IVLAGVHFMAETAKLLNPDKTVLIPDLGAGCSLAESITAEDVRLMRQRYPSVPVVTYVNTSAAVKAESDICCTSGNALAV
VKSLGAPRVIMLPDEYLAKNIAAQTKVEIIAWKGRCEVHERFTAADIRELREAHPGISVLAHPECPPEVVAEADFAGSTA
AMSDYVARHRPARVVLMTECSMSDNVAVEHPEVDFVRPCNLCPHMKRITLANIRTALEENRHVVTIDPHVAERARWAVER
MLFV

Sequences:

>Translated_324_residues
MSAVLPSSASLYDRVRRVIPPIEWSVFVEDIDAILNLKRQRNAVILAHNYQTPEIFHCVADIVGDSLALARKAMTVDAEI
IVLAGVHFMAETAKLLNPDKTVLIPDLGAGCSLAESITAEDVRLMRQRYPSVPVVTYVNTSAAVKAESDICCTSGNALAV
VKSLGAPRVIMLPDEYLAKNIAAQTKVEIIAWKGRCEVHERFTAADIRELREAHPGISVLAHPECPPEVVAEADFAGSTA
AMSDYVARHRPARVVLMTECSMSDNVAVEHPEVDFVRPCNLCPHMKRITLANIRTALEENRHVVTIDPHVAERARWAVER
MLFV
>Mature_323_residues
SAVLPSSASLYDRVRRVIPPIEWSVFVEDIDAILNLKRQRNAVILAHNYQTPEIFHCVADIVGDSLALARKAMTVDAEII
VLAGVHFMAETAKLLNPDKTVLIPDLGAGCSLAESITAEDVRLMRQRYPSVPVVTYVNTSAAVKAESDICCTSGNALAVV
KSLGAPRVIMLPDEYLAKNIAAQTKVEIIAWKGRCEVHERFTAADIRELREAHPGISVLAHPECPPEVVAEADFAGSTAA
MSDYVARHRPARVVLMTECSMSDNVAVEHPEVDFVRPCNLCPHMKRITLANIRTALEENRHVVTIDPHVAERARWAVERM
LFV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=35.8064516129032, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA1_RHILO (Q98AV7)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_106429.1
- ProteinModelPortal:   Q98AV7
- SMR:   Q98AV7
- GeneID:   1229088
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll5835
- NMPDR:   fig|266835.1.peg.4532
- HOGENOM:   HBG291157
- OMA:   CHPECNP
- ProtClustDB:   PRK09375
- GO:   GO:0005737
- HAMAP:   MF_00568
- InterPro:   IPR003473
- InterPro:   IPR023066
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 35660; Mature: 35528

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: BINDING 48-48 BINDING 66-66 BINDING 137-137 BINDING 154-154 BINDING 222-222 BINDING 239-239

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVLPSSASLYDRVRRVIPPIEWSVFVEDIDAILNLKRQRNAVILAHNYQTPEIFHCVA
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
DIVGDSLALARKAMTVDAEIIVLAGVHFMAETAKLLNPDKTVLIPDLGAGCSLAESITAE
HHHCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
DVRLMRQRYPSVPVVTYVNTSAAVKAESDICCTSGNALAVVKSLGAPRVIMLPDEYLAKN
HHHHHHHHCCCCCEEEEECCCEEEECCCCEEEECCCCEEEEHHCCCCEEEECCHHHHHHH
IAAQTKVEIIAWKGRCEVHERFTAADIRELREAHPGISVLAHPECPPEVVAEADFAGSTA
HHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCCHH
AMSDYVARHRPARVVLMTECSMSDNVAVEHPEVDFVRPCNLCPHMKRITLANIRTALEEN
HHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
RHVVTIDPHVAERARWAVERMLFV
CEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAVLPSSASLYDRVRRVIPPIEWSVFVEDIDAILNLKRQRNAVILAHNYQTPEIFHCVA
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
DIVGDSLALARKAMTVDAEIIVLAGVHFMAETAKLLNPDKTVLIPDLGAGCSLAESITAE
HHHCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHH
DVRLMRQRYPSVPVVTYVNTSAAVKAESDICCTSGNALAVVKSLGAPRVIMLPDEYLAKN
HHHHHHHHCCCCCEEEEECCCEEEECCCCEEEECCCCEEEEHHCCCCEEEECCHHHHHHH
IAAQTKVEIIAWKGRCEVHERFTAADIRELREAHPGISVLAHPECPPEVVAEADFAGSTA
HHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCCHH
AMSDYVARHRPARVVLMTECSMSDNVAVEHPEVDFVRPCNLCPHMKRITLANIRTALEEN
HHHHHHHHCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
RHVVTIDPHVAERARWAVERMLFV
CEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968