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The map label for this gene is fabH [H]

Identifier: 13474852

GI number: 13474852

Start: 4699834

End: 4700817

Strand: Reverse

Name: fabH [H]

Synonym: mll5827

Alternate gene names: 13474852

Gene position: 4700817-4699834 (Counterclockwise)

Preceding gene: 13474853

Following gene: 13474851

Centisome position: 66.81

GC content: 65.85

Gene sequence:

>984_bases
ATGAGCAAGTCGTCGCGCATTCTCGGGTTCGGTCATCATACGCCTGGGCGCAAGGTGGCGAATGCCGAGATCGAGAACAA
TCTCGGCCTCGAGCCGGGCTGGATCGAAAGGCGTACCGGAATCCGTTCGCGCTTCTGGGCAACGGACGGAGACACGCTGT
CTGGTCTTGCCACGCAGGCTGGCGACATCGCGCTGGCGAACGCCGGTATTGACCGCAGCGACATCGGGCTGCTGTTGCTT
GCCACCTCGACACCCGACCACCTTCTGCCGCCCAGTGCACCCTTGGTCGCGCACAAGCTCGGCCTTGGCCGCGCAGGCGC
GGTCGATCTGACCGGCGCCTGCGCCGGCTTCGTCTATGCGCTGATGTTCGCGGACGGGTTCACCCGCCTGCACGGCAAAC
CAGCGCTGGTCATCGCCGCCAACATCCTCAGCCGCCGCATCAATCCAGCCGAGCGCGCGAGCTCAGTCCTTTTCGCCGAT
GCCGCCGGCGCCCTGGTGATCGGTCCTTGCGAGGATCCCTATCAGGGTATTCTCGGCGCTTCGGTGGATTCCGACGGCTC
GCGCTACGGGCTGATCCAGATCCCGGCAGGCGGAAGCAACACCCCGTTCCATGGCGAGCTCGATCTCGAGCAGACCCGCA
TGACGATCACCGACGGCCGCGAAGTGTTCGCCAAGGCGGTTGAGATGATGACTGCCTGCTCGCAGGACGCACTCGCGGCG
GCCCGGATGCGGCCGCAGGACATCGATCGGTTCGTACCGCACCAGGCCAATGCCCGCATTTTCGATGCGGTCGGGCGAAA
CCTCGGCATCGCCGATGAAGCGATCGTCAAGACGATCGCCGAGTATGGCAACTCTTCCGCCGCGACGATCCCGCTCTCGC
TGTCGCTCGCCCATCGGGCGGCGCCGTTCCGGCCGGGGGAGAAGGTTCTTCTGGCGGCCGCGGGTGCGGGTCTTAGCGGC
GGTGCGCTCGTCGTTGGAATTTAG

Upstream 100 bases:

>100_bases
ATGTCCTCTATCTTCTCCCGCCCTATTGCATCACCGGCGGCGAGTTGGACGCACTCTACGACGCGATCGAGGAGGCCGCC
GAACGCTTCGGGTCTAGGCC

Downstream 100 bases:

>100_bases
CCGCGCGAACCGAACTGCCAAGACTGACCTTGAACGATGAATACAGGGACAACGACCAATGCGAAAACTAGTCGCCGGCA
AGCTGCACGGCATCCACGTC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MSKSSRILGFGHHTPGRKVANAEIENNLGLEPGWIERRTGIRSRFWATDGDTLSGLATQAGDIALANAGIDRSDIGLLLL
ATSTPDHLLPPSAPLVAHKLGLGRAGAVDLTGACAGFVYALMFADGFTRLHGKPALVIAANILSRRINPAERASSVLFAD
AAGALVIGPCEDPYQGILGASVDSDGSRYGLIQIPAGGSNTPFHGELDLEQTRMTITDGREVFAKAVEMMTACSQDALAA
ARMRPQDIDRFVPHQANARIFDAVGRNLGIADEAIVKTIAEYGNSSAATIPLSLSLAHRAAPFRPGEKVLLAAAGAGLSG
GALVVGI

Sequences:

>Translated_327_residues
MSKSSRILGFGHHTPGRKVANAEIENNLGLEPGWIERRTGIRSRFWATDGDTLSGLATQAGDIALANAGIDRSDIGLLLL
ATSTPDHLLPPSAPLVAHKLGLGRAGAVDLTGACAGFVYALMFADGFTRLHGKPALVIAANILSRRINPAERASSVLFAD
AAGALVIGPCEDPYQGILGASVDSDGSRYGLIQIPAGGSNTPFHGELDLEQTRMTITDGREVFAKAVEMMTACSQDALAA
ARMRPQDIDRFVPHQANARIFDAVGRNLGIADEAIVKTIAEYGNSSAATIPLSLSLAHRAAPFRPGEKVLLAAAGAGLSG
GALVVGI
>Mature_326_residues
SKSSRILGFGHHTPGRKVANAEIENNLGLEPGWIERRTGIRSRFWATDGDTLSGLATQAGDIALANAGIDRSDIGLLLLA
TSTPDHLLPPSAPLVAHKLGLGRAGAVDLTGACAGFVYALMFADGFTRLHGKPALVIAANILSRRINPAERASSVLFADA
AGALVIGPCEDPYQGILGASVDSDGSRYGLIQIPAGGSNTPFHGELDLEQTRMTITDGREVFAKAVEMMTACSQDALAAA
RMRPQDIDRFVPHQANARIFDAVGRNLGIADEAIVKTIAEYGNSSAATIPLSLSLAHRAAPFRPGEKVLLAAAGAGLSGG
ALVVGI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=34.7826086956522, Blast_Score=191, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 33962; Mature: 33831

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSSRILGFGHHTPGRKVANAEIENNLGLEPGWIERRTGIRSRFWATDGDTLSGLATQA
CCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHCCCCHHEECCCCCCHHHHHHCC
GDIALANAGIDRSDIGLLLLATSTPDHLLPPSAPLVAHKLGLGRAGAVDLTGACAGFVYA
CCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEECHHHHHHHHHH
LMFADGFTRLHGKPALVIAANILSRRINPAERASSVLFADAAGALVIGPCEDPYQGILGA
HHHHCCHHHHCCCCEEEEEEHHHHHCCCHHHHHCEEEEEECCCEEEECCCCCHHHHHCCC
SVDSDGSRYGLIQIPAGGSNTPFHGELDLEQTRMTITDGREVFAKAVEMMTACSQDALAA
CCCCCCCEEEEEEECCCCCCCCCCCEECHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHH
ARMRPQDIDRFVPHQANARIFDAVGRNLGIADEAIVKTIAEYGNSSAATIPLSLSLAHRA
HHCCHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEHHHC
APFRPGEKVLLAAAGAGLSGGALVVGI
CCCCCCCEEEEEEECCCCCCCEEEEEC
>Mature Secondary Structure 
SKSSRILGFGHHTPGRKVANAEIENNLGLEPGWIERRTGIRSRFWATDGDTLSGLATQA
CCCCCEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHCCCCHHEECCCCCCHHHHHHCC
GDIALANAGIDRSDIGLLLLATSTPDHLLPPSAPLVAHKLGLGRAGAVDLTGACAGFVYA
CCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEECHHHHHHHHHH
LMFADGFTRLHGKPALVIAANILSRRINPAERASSVLFADAAGALVIGPCEDPYQGILGA
HHHHCCHHHHCCCCEEEEEEHHHHHCCCHHHHHCEEEEEECCCEEEECCCCCHHHHHCCC
SVDSDGSRYGLIQIPAGGSNTPFHGELDLEQTRMTITDGREVFAKAVEMMTACSQDALAA
CCCCCCCEEEEEEECCCCCCCCCCCEECHHHHEEEECCCHHHHHHHHHHHHHCCHHHHHH
ARMRPQDIDRFVPHQANARIFDAVGRNLGIADEAIVKTIAEYGNSSAATIPLSLSLAHRA
HHCCHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEHHHC
APFRPGEKVLLAAAGAGLSGGALVVGI
CCCCCCCEEEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA