Click here to switch to the map view.

The map label for this gene is dppC [H]

Identifier: 13474518

GI number: 13474518

Start: 4335771

End: 4336682

Strand: Direct

Name: dppC [H]

Synonym: mlr5418

Alternate gene names: 13474518

Gene position: 4335771-4336682 (Clockwise)

Preceding gene: 13474517

Following gene: 13474519

Centisome position: 61.62

GC content: 66.23

Gene sequence:

>912_bases
ATGAGCCAGTCGACCGAAATCGCCCCGATGGCCGCCGGCAACCCGGATCGCCTCACCGGCCTCAGGACCTTCTGGTATTA
TTTCTCGGTGAACCGCGGGGCCGTTATCGGCCTGTTCGTCTTCATCCTTTTGGTGCTGGCGGCGCTGTTTGCGCCACTGC
TGGCTCCCTATGCACCCGACGTCCAGGACAAGACCGCATTCCTGCGGCCTCCGGCCTGGCAGGCAGGCGGCAGCTCGCAA
TATCTGCTCGGCACCGACCCGGTTGGGCGCGACATCCTTTCACGCCTGCTCTACGGCGCGCGCTTCTCGCTGCTGATCGG
CGCTGTCGTCGTCTCGCTGGCGCTCGCCGGCGGCATCACGCTCGGCCTGCTGGCCGGCTATTTCCGCGGCTGGGTCGACG
TGGCGATCATGCGCGTCATGGACCTCATCCTGGCCTTCCCGTCGCTGTTGCTGGCGCTGGTGATGGTCACCATCCTCGGC
CCTGGCCTGTTCAATGCGATGCTGGCCATCGCGCTTGTCCTGCAGCCGCATTTCGCGCGGCTGGTGCGCGCCGCGGTGAT
GGCCGAGAAGAGCCGCGAATATGTCGTGGCGGCAAAGGTCGCCGGCGCCGGGCATCTCAGGCTGATGCTTCGCACCATCC
TGCCCAATTGCCTGGGGCCGCTGATTGTCCAGGGCACCTTGTCCTTCTCCAACGCCATCCTCGAAGCGGCAGCCCTCGGC
TTCCTCGGCCTCGGCGCCCAGCCGCCGACGCCGGAATGGGGCACCATGCTTGCTACGGCGCGCGAATTCATCCTGCGCGC
CTGGTGGGTGGTGACGTTCCCGGGTCTCGCCATCCTCATCACCGTGCTTGCCATCAATCTGATCGGCGACGGCCTGCGCG
ATGCGCTCGATCCCAAGCTCAGGAGGTCATGA

Upstream 100 bases:

>100_bases
TGCAGTCTGGCCTGCTGTTGATTGCCCTTATCGTCATGGCCGTGAACTTGATCGTCGATGTGCTCTATGCAGTCATCAAC
CCACGCATAAGGGCGGCGTG

Downstream 100 bases:

>100_bases
TGGCGCTGCTCGACATCCAGAACCTCGTCGTCGAATTCCAGACCGCATCCGGTTCCTTCCGCGCCGTCGACGGCGTGTCG
CTGCATGTGGACGAGCGCGA

Product: ABC transporter permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSQSTEIAPMAAGNPDRLTGLRTFWYYFSVNRGAVIGLFVFILLVLAALFAPLLAPYAPDVQDKTAFLRPPAWQAGGSSQ
YLLGTDPVGRDILSRLLYGARFSLLIGAVVVSLALAGGITLGLLAGYFRGWVDVAIMRVMDLILAFPSLLLALVMVTILG
PGLFNAMLAIALVLQPHFARLVRAAVMAEKSREYVVAAKVAGAGHLRLMLRTILPNCLGPLIVQGTLSFSNAILEAAALG
FLGLGAQPPTPEWGTMLATAREFILRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLRRS

Sequences:

>Translated_303_residues
MSQSTEIAPMAAGNPDRLTGLRTFWYYFSVNRGAVIGLFVFILLVLAALFAPLLAPYAPDVQDKTAFLRPPAWQAGGSSQ
YLLGTDPVGRDILSRLLYGARFSLLIGAVVVSLALAGGITLGLLAGYFRGWVDVAIMRVMDLILAFPSLLLALVMVTILG
PGLFNAMLAIALVLQPHFARLVRAAVMAEKSREYVVAAKVAGAGHLRLMLRTILPNCLGPLIVQGTLSFSNAILEAAALG
FLGLGAQPPTPEWGTMLATAREFILRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLRRS
>Mature_302_residues
SQSTEIAPMAAGNPDRLTGLRTFWYYFSVNRGAVIGLFVFILLVLAALFAPLLAPYAPDVQDKTAFLRPPAWQAGGSSQY
LLGTDPVGRDILSRLLYGARFSLLIGAVVVSLALAGGITLGLLAGYFRGWVDVAIMRVMDLILAFPSLLLALVMVTILGP
GLFNAMLAIALVLQPHFARLVRAAVMAEKSREYVVAAKVAGAGHLRLMLRTILPNCLGPLIVQGTLSFSNAILEAAALGF
LGLGAQPPTPEWGTMLATAREFILRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKLRRS

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=302, Percent_Identity=61.5894039735099, Blast_Score=314, Evalue=6e-87,
Organism=Escherichia coli, GI1787760, Length=302, Percent_Identity=44.0397350993377, Blast_Score=230, Evalue=9e-62,
Organism=Escherichia coli, GI1787054, Length=289, Percent_Identity=44.2906574394464, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1787549, Length=277, Percent_Identity=43.6823104693141, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=41.2244897959184, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1787498, Length=284, Percent_Identity=35.2112676056338, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1788505, Length=223, Percent_Identity=29.5964125560538, Blast_Score=98, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32436; Mature: 32305

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSTEIAPMAAGNPDRLTGLRTFWYYFSVNRGAVIGLFVFILLVLAALFAPLLAPYAPD
CCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
VQDKTAFLRPPAWQAGGSSQYLLGTDPVGRDILSRLLYGARFSLLIGAVVVSLALAGGIT
CCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLAGYFRGWVDVAIMRVMDLILAFPSLLLALVMVTILGPGLFNAMLAIALVLQPHFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LVRAAVMAEKSREYVVAAKVAGAGHLRLMLRTILPNCLGPLIVQGTLSFSNAILEAAALG
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGAQPPTPEWGTMLATAREFILRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RRS
CCC
>Mature Secondary Structure 
SQSTEIAPMAAGNPDRLTGLRTFWYYFSVNRGAVIGLFVFILLVLAALFAPLLAPYAPD
CCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
VQDKTAFLRPPAWQAGGSSQYLLGTDPVGRDILSRLLYGARFSLLIGAVVVSLALAGGIT
CCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLLAGYFRGWVDVAIMRVMDLILAFPSLLLALVMVTILGPGLFNAMLAIALVLQPHFAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LVRAAVMAEKSREYVVAAKVAGAGHLRLMLRTILPNCLGPLIVQGTLSFSNAILEAAALG
HHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGAQPPTPEWGTMLATAREFILRAWWVVTFPGLAILITVLAINLIGDGLRDALDPKL
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RRS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]