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The map label for this gene is dhaR [H]

Identifier: 13474463

GI number: 13474463

Start: 4274003

End: 4274596

Strand: Direct

Name: dhaR [H]

Synonym: mlr5353

Alternate gene names: 13474463

Gene position: 4274003-4274596 (Clockwise)

Preceding gene: 13474461

Following gene: 13474464

Centisome position: 60.74

GC content: 64.98

Gene sequence:

>594_bases
ATGGCTAGACAATCACTCCGCGAAAAACTTCTCGACGCCGGTTTCCGGACCATCTGGAATTCAGGCTATGCCGCCGCCGG
CGTGCGCGACATCGTTGCCGCCGCCGACGCCCGGCCGGGATCCTTCACCAATCATTTCGCCTCGAAGGAGGCGTTCGCCG
GCGAAGTGCTGGACCGCTACTTCACCTATGTCAGTGGGCTGGTCGAGGCTGCGCTGGCGCAGGACGGCACGCCGCCCATA
GGCAGGCTGCGCCGCTACCTCGACGTCATCACCTCGAAGCTCGAGGCGCATGACTGGGCGCGCGGCTGCATGATCGGCAA
TCTCAGCCTCGAGGCAGCGGTGCACAGCGAGCCGTTGCGCGTGCAACTCGTCGCCATCTTCGAGCGCTGGCGCCAGCCCT
TCGCCGTCTGCATCGCCGAAGGCCAGGCGGCCGGCGACATCGCCAAGACCTTCGAGGCCGAGGACCTCGCCGACTTCCTG
CTGTCGTCCTGGCAGGGCGCCATGCTGCGCATGAAGGTCGAGCGCAGCCCCGAACCGCTCGAGCGGTTCAAGAAAATCAT
CTTCAACACAGCGTTTGCAAAGGAGACCCCATGA

Upstream 100 bases:

>100_bases
GAGGACGCTCTTGCAGTGCCACCCCGCTCGTCACTTGCCAACATCGGATACGGTAAAAAGATGCGCTTGACATAAATACG
TACGTACGTATTATTTGGAT

Downstream 100 bases:

>100_bases
GTTCGAAAGCCAACCCGCCTCAGCCGGTCGCCACCGCGCCGAAACGTTCGCAGATTCCCATACTCGATTCGACCATGTCC
TATGTCGAGGCGGGAGCGTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MARQSLREKLLDAGFRTIWNSGYAAAGVRDIVAAADARPGSFTNHFASKEAFAGEVLDRYFTYVSGLVEAALAQDGTPPI
GRLRRYLDVITSKLEAHDWARGCMIGNLSLEAAVHSEPLRVQLVAIFERWRQPFAVCIAEGQAAGDIAKTFEAEDLADFL
LSSWQGAMLRMKVERSPEPLERFKKIIFNTAFAKETP

Sequences:

>Translated_197_residues
MARQSLREKLLDAGFRTIWNSGYAAAGVRDIVAAADARPGSFTNHFASKEAFAGEVLDRYFTYVSGLVEAALAQDGTPPI
GRLRRYLDVITSKLEAHDWARGCMIGNLSLEAAVHSEPLRVQLVAIFERWRQPFAVCIAEGQAAGDIAKTFEAEDLADFL
LSSWQGAMLRMKVERSPEPLERFKKIIFNTAFAKETP
>Mature_196_residues
ARQSLREKLLDAGFRTIWNSGYAAAGVRDIVAAADARPGSFTNHFASKEAFAGEVLDRYFTYVSGLVEAALAQDGTPPIG
RLRRYLDVITSKLEAHDWARGCMIGNLSLEAAVHSEPLRVQLVAIFERWRQPFAVCIAEGQAAGDIAKTFEAEDLADFLL
SSWQGAMLRMKVERSPEPLERFKKIIFNTAFAKETP

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 21838; Mature: 21707

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQSLREKLLDAGFRTIWNSGYAAAGVRDIVAAADARPGSFTNHFASKEAFAGEVLDRY
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FTYVSGLVEAALAQDGTPPIGRLRRYLDVITSKLEAHDWARGCMIGNLSLEAAVHSEPLR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHH
VQLVAIFERWRQPFAVCIAEGQAAGDIAKTFEAEDLADFLLSSWQGAMLRMKVERSPEPL
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHH
ERFKKIIFNTAFAKETP
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARQSLREKLLDAGFRTIWNSGYAAAGVRDIVAAADARPGSFTNHFASKEAFAGEVLDRY
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
FTYVSGLVEAALAQDGTPPIGRLRRYLDVITSKLEAHDWARGCMIGNLSLEAAVHSEPLR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHH
VQLVAIFERWRQPFAVCIAEGQAAGDIAKTFEAEDLADFLLSSWQGAMLRMKVERSPEPL
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCHH
ERFKKIIFNTAFAKETP
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]