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The map label for this gene is glmS [H]

Identifier: 13473995

GI number: 13473995

Start: 3789235

End: 3790269

Strand: Reverse

Name: glmS [H]

Synonym: mll4767

Alternate gene names: 13473995

Gene position: 3790269-3789235 (Counterclockwise)

Preceding gene: 13473996

Following gene: 13473994

Centisome position: 53.87

GC content: 67.05

Gene sequence:

>1035_bases
ATGATCTCCAACACCACCCATATGCAACGCGAGATCGAGGAGATCCCGAAGGCCGTCGCCCGCCTGCTCGACGGCTCCGG
CGCCGCGCTCGCCGAGGCCGGGCGCGGTATCAAGGAGCGCGACCCGCATTTCGTTGTCACCGTGGCGCGCGGCTCGTCCG
ACCATGCCGCGACCTTCATGAAATATGCCGTGGAGCTGACCGCGGGCCTTGCCGTCGCTTCGGTCGGTCCGTCCATTGCC
TCGATCTATGGCCGCAAGCTGAGGCTCGACGGCTCGGCCTGTCTGGCGATCTCGCAGTCGGGCAAGAGCCCCGACATCGT
CGCCATGGCCGAAACCGCACGCGCCGGCGGCGCGCTGACCATCGCCATCACCAACACCGCCGACTCGCCGCTGGCGCGCG
CCTCGGACTATGCGATCGACATCCTTGCCGGCCCGGAGCGCAGCGTCGCGGCGACCAAGACCTTCGTCAATTCCGCCGTC
GCCGGTCTTGCCCTGATGGCGCATTCCACCGGCGACGAAGCTCTTCTGGCAGCGCTGGCCCGATTGCCAGAGCATTTCGG
CAAGGCGATCGCCTGCGACTGGATGAGCGTGCTGGCTGAAACCATCGAGAAGCAGAAATCGCTGTTCATCCTTGGCCGCG
GCCCGTCGGCGGCGATGGCCAACGAGGCGGCGCTTAAGTTCAAGGAGACCTGCGGCATGCATGCCGAGGCCTATAGCGCG
GCCGAGGTCATGCATGGCCCGCTGGCGCTGATCGGTCCCGACTTTCCGGTGCTGGCTCTGGCCGCGCGCGATGCGTCAGA
ACCCTCCATCACTGAGGCGGCCGACGGGCTGGCGGCCAAGGGGGCGCCGGTGTTCGTCACTTCGGCGCTTGCCAACCGCG
CCACGCGCCTGCCGCATGTCGCCACCGGTCATCCGCTGACCGATCCGCTGACACTGATCGTTTCGTTCTACGTGTTCGTC
GAGGCCTTCGCGCGCCATCGCGGCCTCGATCCGGACACGCCGCGCAATCTTCGCAAGGTGACGGAGACAGTATGA

Upstream 100 bases:

>100_bases
GCGGCAAGGTGATCGAATTCACCCGCTCCATCTACCGGGGCGACGCCTATGATTTCGTCGCCGAACTGCGGCTGACAGGG
CCGAGCGAAGAGGGCCGACC

Downstream 100 bases:

>100_bases
GCGACCGTTTTGCCCTGACTGGCGCCCGCATTTTCGACGGTGACGACTGGCATGACGATGCCGCACTCGTCGTGCGCGAC
GGCCTTGTCGAGGCGATTGT

Product: glucosamine-fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MISNTTHMQREIEEIPKAVARLLDGSGAALAEAGRGIKERDPHFVVTVARGSSDHAATFMKYAVELTAGLAVASVGPSIA
SIYGRKLRLDGSACLAISQSGKSPDIVAMAETARAGGALTIAITNTADSPLARASDYAIDILAGPERSVAATKTFVNSAV
AGLALMAHSTGDEALLAALARLPEHFGKAIACDWMSVLAETIEKQKSLFILGRGPSAAMANEAALKFKETCGMHAEAYSA
AEVMHGPLALIGPDFPVLALAARDASEPSITEAADGLAAKGAPVFVTSALANRATRLPHVATGHPLTDPLTLIVSFYVFV
EAFARHRGLDPDTPRNLRKVTETV

Sequences:

>Translated_344_residues
MISNTTHMQREIEEIPKAVARLLDGSGAALAEAGRGIKERDPHFVVTVARGSSDHAATFMKYAVELTAGLAVASVGPSIA
SIYGRKLRLDGSACLAISQSGKSPDIVAMAETARAGGALTIAITNTADSPLARASDYAIDILAGPERSVAATKTFVNSAV
AGLALMAHSTGDEALLAALARLPEHFGKAIACDWMSVLAETIEKQKSLFILGRGPSAAMANEAALKFKETCGMHAEAYSA
AEVMHGPLALIGPDFPVLALAARDASEPSITEAADGLAAKGAPVFVTSALANRATRLPHVATGHPLTDPLTLIVSFYVFV
EAFARHRGLDPDTPRNLRKVTETV
>Mature_344_residues
MISNTTHMQREIEEIPKAVARLLDGSGAALAEAGRGIKERDPHFVVTVARGSSDHAATFMKYAVELTAGLAVASVGPSIA
SIYGRKLRLDGSACLAISQSGKSPDIVAMAETARAGGALTIAITNTADSPLARASDYAIDILAGPERSVAATKTFVNSAV
AGLALMAHSTGDEALLAALARLPEHFGKAIACDWMSVLAETIEKQKSLFILGRGPSAAMANEAALKFKETCGMHAEAYSA
AEVMHGPLALIGPDFPVLALAARDASEPSITEAADGLAAKGAPVFVTSALANRATRLPHVATGHPLTDPLTLIVSFYVFV
EAFARHRGLDPDTPRNLRKVTETV

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=368, Percent_Identity=31.25, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI4826742, Length=366, Percent_Identity=30.8743169398907, Blast_Score=129, Evalue=5e-30,
Organism=Escherichia coli, GI1790167, Length=357, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082251, Length=304, Percent_Identity=23.3552631578947, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532899, Length=373, Percent_Identity=31.6353887399464, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17532897, Length=373, Percent_Identity=31.6353887399464, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17539970, Length=373, Percent_Identity=31.9034852546917, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322745, Length=267, Percent_Identity=29.9625468164794, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6323731, Length=209, Percent_Identity=23.9234449760766, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357745, Length=367, Percent_Identity=30.5177111716621, Blast_Score=127, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 35789; Mature: 35789

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNTTHMQREIEEIPKAVARLLDGSGAALAEAGRGIKERDPHFVVTVARGSSDHAATFM
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
KYAVELTAGLAVASVGPSIASIYGRKLRLDGSACLAISQSGKSPDIVAMAETARAGGALT
HHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCCCEEE
IAITNTADSPLARASDYAIDILAGPERSVAATKTFVNSAVAGLALMAHSTGDEALLAALA
EEEECCCCCCCHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RLPEHFGKAIACDWMSVLAETIEKQKSLFILGRGPSAAMANEAALKFKETCGMHAEAYSA
HHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHH
AEVMHGPLALIGPDFPVLALAARDASEPSITEAADGLAAKGAPVFVTSALANRATRLPHV
HHHHCCCEEEECCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCC
ATGHPLTDPLTLIVSFYVFVEAFARHRGLDPDTPRNLRKVTETV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MISNTTHMQREIEEIPKAVARLLDGSGAALAEAGRGIKERDPHFVVTVARGSSDHAATFM
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHH
KYAVELTAGLAVASVGPSIASIYGRKLRLDGSACLAISQSGKSPDIVAMAETARAGGALT
HHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCEEEEEECCCCCCCEEEEECCCCCCCEEE
IAITNTADSPLARASDYAIDILAGPERSVAATKTFVNSAVAGLALMAHSTGDEALLAALA
EEEECCCCCCCHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RLPEHFGKAIACDWMSVLAETIEKQKSLFILGRGPSAAMANEAALKFKETCGMHAEAYSA
HHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHH
AEVMHGPLALIGPDFPVLALAARDASEPSITEAADGLAAKGAPVFVTSALANRATRLPHV
HHHHCCCEEEECCCCCEEEEEECCCCCCCHHHHHCCCCCCCCCCEEHHHHHHHHHCCCCC
ATGHPLTDPLTLIVSFYVFVEAFARHRGLDPDTPRNLRKVTETV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]