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The map label for this gene is nagA [H]

Identifier: 13473994

GI number: 13473994

Start: 3788066

End: 3789238

Strand: Reverse

Name: nagA [H]

Synonym: mll4766

Alternate gene names: 13473994

Gene position: 3789238-3788066 (Counterclockwise)

Preceding gene: 13473995

Following gene: 13473993

Centisome position: 53.85

GC content: 67.69

Gene sequence:

>1173_bases
ATGAGCGACCGTTTTGCCCTGACTGGCGCCCGCATTTTCGACGGTGACGACTGGCATGACGATGCCGCACTCGTCGTGCG
CGACGGCCTTGTCGAGGCGATTGTGCCCTCCGGCGCCATTGCCAGGGATGTCCGCGCCGTCGACACCGGTGGCGGCATGC
TGGTGCCGGGCTTCGTCGACATCCAGGTCAATGGCGGCGGCGGGGTCATGCTCAACGACCACCCCGATGTTGCCTCGATC
GAAACCATCTGCCGGGCGCATGCACCCTTCGGCACGACGGCGCTGCTGCCGACGCTGATCACCGACACGCCCGCGATCAC
CGCTGCCGCCATCGCCGCCGGCGAGGCCGCCGCGCTGCAAAAGGTGCCCAGCTTCCTCGGCCTGCATCTGGAAGGCCCGC
ACCTGTCGATCGCGCGCAAGGGCGCGCATGATCCGGCGCTGATCCGGCCGATGACGGATGCCGACCAGGTGATGCTGATC
GCGGCGCGGCCAAAGCTGCCGGTGCTGCTCACCACGATCGCGCCGGAATCCGTCGATCCCACCCGTGTTGCGGCCTTGGC
CAAGGCCGGCATCATCGTCAGCCTCGGCCATTCCGATACGGGCTACGCCACGGCAAAGGGCTTCGCCGAGGCCGGCGCCG
CCGTGGTCACGCATCTGTTCAACGCGATGAGCCAGATCGGCAACCGCGAGCCCGGCCTCGTCGGCGCGGCCATCGACATC
GGCACATTGTCCGCCGGGCTGATCGCCGACGGCATCCATGTCCATCCGGCAGCCATCAGGATCGCGCTCGACGCCAAACA
GGGGCCGGGCAAGATCGTGCTGGTCACCGACGCCATGGCGACGATCGGCACCGACATGACCTCGTTCACGCTCAACGGCC
GCACCATCTACCGCAAGGACGGGAGCCTGCGGCTTGCCGACGGCACGCTGGCCGGCGCCGACCTCGACATGATCTCGGCC
GTGCGGTTCATGCACAATATCGTCGGTGTCGATCTGTCCGAGGCCTTGCGCATGGCTTCGCTCTATCCGGCGCAGGCGAT
CGGCCAGTCGCACCGGCTTGGCCGCCTGGCCAACGGCACGGTGGCCGACATCGTTGCGCTGTCGGACGGTCTCGACATAA
GAAGCGTGTGGATCGGCGGCGACAAGGTGTTCGAGGCCGGCGCTTCACGCTAA

Upstream 100 bases:

>100_bases
CACTGATCGTTTCGTTCTACGTGTTCGTCGAGGCCTTCGCGCGCCATCGCGGCCTCGATCCGGACACGCCGCGCAATCTT
CGCAAGGTGACGGAGACAGT

Downstream 100 bases:

>100_bases
GAGCGGGGCCATGCAGACAATCGATTGTGTCGTCGCCGGAGCGGGCGTCGTCGGGATTGCCGTCGCCAGGGCGCTTGCCG
TGTCGGGCCGCGAGGTGGTG

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSDRFALTGARIFDGDDWHDDAALVVRDGLVEAIVPSGAIARDVRAVDTGGGMLVPGFVDIQVNGGGGVMLNDHPDVASI
ETICRAHAPFGTTALLPTLITDTPAITAAAIAAGEAAALQKVPSFLGLHLEGPHLSIARKGAHDPALIRPMTDADQVMLI
AARPKLPVLLTTIAPESVDPTRVAALAKAGIIVSLGHSDTGYATAKGFAEAGAAVVTHLFNAMSQIGNREPGLVGAAIDI
GTLSAGLIADGIHVHPAAIRIALDAKQGPGKIVLVTDAMATIGTDMTSFTLNGRTIYRKDGSLRLADGTLAGADLDMISA
VRFMHNIVGVDLSEALRMASLYPAQAIGQSHRLGRLANGTVADIVALSDGLDIRSVWIGGDKVFEAGASR

Sequences:

>Translated_390_residues
MSDRFALTGARIFDGDDWHDDAALVVRDGLVEAIVPSGAIARDVRAVDTGGGMLVPGFVDIQVNGGGGVMLNDHPDVASI
ETICRAHAPFGTTALLPTLITDTPAITAAAIAAGEAAALQKVPSFLGLHLEGPHLSIARKGAHDPALIRPMTDADQVMLI
AARPKLPVLLTTIAPESVDPTRVAALAKAGIIVSLGHSDTGYATAKGFAEAGAAVVTHLFNAMSQIGNREPGLVGAAIDI
GTLSAGLIADGIHVHPAAIRIALDAKQGPGKIVLVTDAMATIGTDMTSFTLNGRTIYRKDGSLRLADGTLAGADLDMISA
VRFMHNIVGVDLSEALRMASLYPAQAIGQSHRLGRLANGTVADIVALSDGLDIRSVWIGGDKVFEAGASR
>Mature_389_residues
SDRFALTGARIFDGDDWHDDAALVVRDGLVEAIVPSGAIARDVRAVDTGGGMLVPGFVDIQVNGGGGVMLNDHPDVASIE
TICRAHAPFGTTALLPTLITDTPAITAAAIAAGEAAALQKVPSFLGLHLEGPHLSIARKGAHDPALIRPMTDADQVMLIA
ARPKLPVLLTTIAPESVDPTRVAALAKAGIIVSLGHSDTGYATAKGFAEAGAAVVTHLFNAMSQIGNREPGLVGAAIDIG
TLSAGLIADGIHVHPAAIRIALDAKQGPGKIVLVTDAMATIGTDMTSFTLNGRTIYRKDGSLRLADGTLAGADLDMISAV
RFMHNIVGVDLSEALRMASLYPAQAIGQSHRLGRLANGTVADIVALSDGLDIRSVWIGGDKVFEAGASR

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=389, Percent_Identity=35.2185089974293, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI224922791, Length=379, Percent_Identity=35.0923482849604, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1786892, Length=383, Percent_Identity=40.2088772845953, Blast_Score=267, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17553768, Length=362, Percent_Identity=30.3867403314917, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281361140, Length=392, Percent_Identity=34.4387755102041, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI19920392, Length=378, Percent_Identity=34.3915343915344, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40091; Mature: 39959

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRFALTGARIFDGDDWHDDAALVVRDGLVEAIVPSGAIARDVRAVDTGGGMLVPGFVD
CCCCEEEECCEEECCCCCCCCCEEEEECCHHHHHCCCCCHHHCCEEEECCCCEEECCEEE
IQVNGGGGVMLNDHPDVASIETICRAHAPFGTTALLPTLITDTPAITAAAIAAGEAAALQ
EEEECCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHH
KVPSFLGLHLEGPHLSIARKGAHDPALIRPMTDADQVMLIAARPKLPVLLTTIAPESVDP
HHHHHHCEEECCCCEEEEECCCCCCEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCH
TRVAALAKAGIIVSLGHSDTGYATAKGFAEAGAAVVTHLFNAMSQIGNREPGLVGAAIDI
HHHHHHHHCCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GTLSAGLIADGIHVHPAAIRIALDAKQGPGKIVLVTDAMATIGTDMTSFTLNGRTIYRKD
CCCCCCHHCCCCEECCEEEEEEEECCCCCCEEEEEECCHHHHCCCCEEEEECCEEEEEEC
GSLRLADGTLAGADLDMISAVRFMHNIVGVDLSEALRMASLYPAQAIGQSHRLGRLANGT
CCEEEECCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
VADIVALSDGLDIRSVWIGGDKVFEAGASR
CEEEEEECCCCCEEEEEECCHHHCCCCCCC
>Mature Secondary Structure 
SDRFALTGARIFDGDDWHDDAALVVRDGLVEAIVPSGAIARDVRAVDTGGGMLVPGFVD
CCCEEEECCEEECCCCCCCCCEEEEECCHHHHHCCCCCHHHCCEEEECCCCEEECCEEE
IQVNGGGGVMLNDHPDVASIETICRAHAPFGTTALLPTLITDTPAITAAAIAAGEAAALQ
EEEECCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHCCCHHHHH
KVPSFLGLHLEGPHLSIARKGAHDPALIRPMTDADQVMLIAARPKLPVLLTTIAPESVDP
HHHHHHCEEECCCCEEEEECCCCCCEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCH
TRVAALAKAGIIVSLGHSDTGYATAKGFAEAGAAVVTHLFNAMSQIGNREPGLVGAAIDI
HHHHHHHHCCEEEEECCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
GTLSAGLIADGIHVHPAAIRIALDAKQGPGKIVLVTDAMATIGTDMTSFTLNGRTIYRKD
CCCCCCHHCCCCEECCEEEEEEEECCCCCCEEEEEECCHHHHCCCCEEEEECCEEEEEEC
GSLRLADGTLAGADLDMISAVRFMHNIVGVDLSEALRMASLYPAQAIGQSHRLGRLANGT
CCEEEECCEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
VADIVALSDGLDIRSVWIGGDKVFEAGASR
CEEEEEECCCCCEEEEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]