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The map label for this gene is suhB

Identifier: 13473355

GI number: 13473355

Start: 3145340

End: 3146140

Strand: Direct

Name: suhB

Synonym: mlr3921

Alternate gene names: 13473355

Gene position: 3145340-3146140 (Clockwise)

Preceding gene: 13473354

Following gene: 13473356

Centisome position: 44.7

GC content: 65.54

Gene sequence:

>801_bases
ATGGCACGCTCAGCCCTTCTCAACGTCATGGTCCAGGCCGCAATGAAGGCCGGCCGCTCGCTGTCACGCGACTTTGGTGA
GGTCCAGAACCTCCAGGTCTCGTTGAAGGGACCCGGCGACTATGTCAGCCAGGCCGACCGCAAGGCCGAGGACATCATCT
TTGCCGAATTGTCGAAGGCGCGCCCGGGCTACGGTTTCCTGATGGAAGAGCGTGGCGCGGTGGAAGGCGAAGACAGCCAG
CACCGCTGGATCGTGGATCCGCTCGACGGCACCACCAATTTCCTGCACGGCATTCCGCTGTTCGCCGTCTCGATCGCGCT
GGAGCGCCAGGGCCAGATCGTAGCCGGCGTCATCTACAATCCGGCCATGGACGAGCTCTACACGACCGAGCGCGGTGGCG
GCGCTTTCATGAACGACCGCCGGCTGCGCGTGGCTGGCCGCATCAAGCTGGTCGACACGGTGATCGGCTGCGGCATGCCG
CATCTGGGACGCGGCCACCACGGCAATTTCCTCGTGGAATTGCGTAACGTCATGGCCGAGGTCTCGGGCGTGCGCCGTCT
CGGTTCGGCCGCGCTCGATCTCGCTTATGTCGCTGCCGGCCGCATGGACGGTTTCTGGGAAACCGGCCTGTCGGCCTGGG
ACATTGCCGCGGGCCTGCTCCTGATCCGCGAAGCCGGCGGCTTCGTCTCGGACATGGATGGCGGGCAGGACATGCTGGAC
AACGGCTCGGTGGTCGCGGGCAACGAGGTCATCCAGCGCGCGCTGCTGAAGGCCGTGAAAAAGCCTCTCTCGGCGCGCTG
A

Upstream 100 bases:

>100_bases
GCCGCCTTTCATCGGCGCCGGCGAACGCATCATCGTCGACACCAACGAAATCACTTACGTGCGCCGCGCCGACTGACGCG
CTGCAGCAGGAAGACATACG

Downstream 100 bases:

>100_bases
AGGGCCGCAGTCGCAAAACCGCCACCTAAGCTTGAAATACTGTCCGGCGGTTGCCCAGATATGGGGTGAAGCAGGACGAT
CGATGGCCAATATCCCGCCC

Product: extragenic suppressor protein SuhB

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MARSALLNVMVQAAMKAGRSLSRDFGEVQNLQVSLKGPGDYVSQADRKAEDIIFAELSKARPGYGFLMEERGAVEGEDSQ
HRWIVDPLDGTTNFLHGIPLFAVSIALERQGQIVAGVIYNPAMDELYTTERGGGAFMNDRRLRVAGRIKLVDTVIGCGMP
HLGRGHHGNFLVELRNVMAEVSGVRRLGSAALDLAYVAAGRMDGFWETGLSAWDIAAGLLLIREAGGFVSDMDGGQDMLD
NGSVVAGNEVIQRALLKAVKKPLSAR

Sequences:

>Translated_266_residues
MARSALLNVMVQAAMKAGRSLSRDFGEVQNLQVSLKGPGDYVSQADRKAEDIIFAELSKARPGYGFLMEERGAVEGEDSQ
HRWIVDPLDGTTNFLHGIPLFAVSIALERQGQIVAGVIYNPAMDELYTTERGGGAFMNDRRLRVAGRIKLVDTVIGCGMP
HLGRGHHGNFLVELRNVMAEVSGVRRLGSAALDLAYVAAGRMDGFWETGLSAWDIAAGLLLIREAGGFVSDMDGGQDMLD
NGSVVAGNEVIQRALLKAVKKPLSAR
>Mature_265_residues
ARSALLNVMVQAAMKAGRSLSRDFGEVQNLQVSLKGPGDYVSQADRKAEDIIFAELSKARPGYGFLMEERGAVEGEDSQH
RWIVDPLDGTTNFLHGIPLFAVSIALERQGQIVAGVIYNPAMDELYTTERGGGAFMNDRRLRVAGRIKLVDTVIGCGMPH
LGRGHHGNFLVELRNVMAEVSGVRRLGSAALDLAYVAAGRMDGFWETGLSAWDIAAGLLLIREAGGFVSDMDGGQDMLDN
GSVVAGNEVIQRALLKAVKKPLSAR

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family

Homologues:

Organism=Homo sapiens, GI7657236, Length=251, Percent_Identity=36.2549800796813, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI5031789, Length=266, Percent_Identity=30.8270676691729, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI221625487, Length=266, Percent_Identity=30.8270676691729, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI221625507, Length=170, Percent_Identity=34.1176470588235, Blast_Score=95, Evalue=6e-20,
Organism=Escherichia coli, GI1788882, Length=259, Percent_Identity=42.4710424710425, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1790659, Length=129, Percent_Identity=31.7829457364341, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193202570, Length=261, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193202572, Length=261, Percent_Identity=31.8007662835249, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320493, Length=208, Percent_Identity=36.5384615384615, Blast_Score=140, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6321836, Length=215, Percent_Identity=30.6976744186047, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357329, Length=240, Percent_Identity=33.75, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24664922, Length=263, Percent_Identity=29.6577946768061, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21357957, Length=268, Percent_Identity=33.5820895522388, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24664918, Length=267, Percent_Identity=31.4606741573034, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21357303, Length=223, Percent_Identity=34.0807174887892, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24664926, Length=230, Percent_Identity=30, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SUHB_RHILO (Q98F59)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104922.1
- ProteinModelPortal:   Q98F59
- SMR:   Q98F59
- GeneID:   1227583
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr3921
- NMPDR:   fig|266835.1.peg.3026
- HOGENOM:   HBG730251
- OMA:   TGFPFKQ
- ProtClustDB:   CLSK863909
- BRENDA:   3.1.3.25
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337
- PANTHER:   PTHR20854
- PRINTS:   PR00377
- PRINTS:   PR01959

Pfam domain/function: PF00459 Inositol_P

EC number: =3.1.3.25

Molecular weight: Translated: 28655; Mature: 28524

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00629 IMP_1; PS00630 IMP_2

Important sites: BINDING 69-69 BINDING 185-185 BINDING 214-214

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSALLNVMVQAAMKAGRSLSRDFGEVQNLQVSLKGPGDYVSQADRKAEDIIFAELSKA
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHC
RPGYGFLMEERGAVEGEDSQHRWIVDPLDGTTNFLHGIPLFAVSIALERQGQIVAGVIYN
CCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
PAMDELYTTERGGGAFMNDRRLRVAGRIKLVDTVIGCGMPHLGRGHHGNFLVELRNVMAE
CHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
VSGVRRLGSAALDLAYVAAGRMDGFWETGLSAWDIAAGLLLIREAGGFVSDMDGGQDMLD
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHC
NGSVVAGNEVIQRALLKAVKKPLSAR
CCCEEECHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARSALLNVMVQAAMKAGRSLSRDFGEVQNLQVSLKGPGDYVSQADRKAEDIIFAELSKA
CHHHHHHHHHHHHHHHCHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHC
RPGYGFLMEERGAVEGEDSQHRWIVDPLDGTTNFLHGIPLFAVSIALERQGQIVAGVIYN
CCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEC
PAMDELYTTERGGGAFMNDRRLRVAGRIKLVDTVIGCGMPHLGRGHHGNFLVELRNVMAE
CHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
VSGVRRLGSAALDLAYVAAGRMDGFWETGLSAWDIAAGLLLIREAGGFVSDMDGGQDMLD
HHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHC
NGSVVAGNEVIQRALLKAVKKPLSAR
CCCEEECHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968