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The map label for this gene is yqfA [H]

Identifier: 13473356

GI number: 13473356

Start: 3146223

End: 3146909

Strand: Direct

Name: yqfA [H]

Synonym: mlr3923

Alternate gene names: 13473356

Gene position: 3146223-3146909 (Clockwise)

Preceding gene: 13473355

Following gene: 13473357

Centisome position: 44.72

GC content: 64.48

Gene sequence:

>687_bases
ATGGCCAATATCCCGCCCCAACTCGAAATCCCCTTTGTCGGGCGCTGGCACTACTCCCGCGCGGAGATGATCGCCGACGG
CATTGTCCATGCTGTCGGCATCGTGTTGGCGATCGCGGCCGGCTCGGCGCTGCTGGCGCTGGCGGCGTTTCGCGTCGGGC
CGGGCGAGTACATCGCCGCCGCCTTCTATGTCGTTTCGCTGCTCACTGTGCTGTCGGTGTCGCTGGCCTACAATCTGTGG
CCGGTGTCGTCCCCGGCCAAATGGGTTCTGCGGCGTTTCGATCACGCCGCGATCTATCTTCTGATCGCCGCCACCTACAC
GCCTTTTCTGGCTCAGCTCGACGCTTCGCCGCTGGCCCGCTGGATGATCGTACTGGTCTGGATCGCGGCGGCGACGGGCA
TCGCCATCAAGGTGTGCTTTCCCGGCCGTTTCGACCGGCTGGCGATCGTCTTCTATCTCGCCATCGGCTGGAGCGGCATC
GTCCTGGTCAAGCCGCTCGTCGAGACGCTGCCGACGACGTCGATCGTGCTCATCGTCGCCGGTGGCGTCGTCTATTCCTG
CGGCGTCATCTTCTTCGCCTGGAAGGGTCTGCGCTTCCACAACGCCCTGTGGCACGGCTTCGTCGTCACTGGCGCGGGCC
TGCATCTGGCGGCCATGGTCGACTGCCTGGTGATAAACCGTTTCTGA

Upstream 100 bases:

>100_bases
CCTCTCTCGGCGCGCTGAAGGGCCGCAGTCGCAAAACCGCCACCTAAGCTTGAAATACTGTCCGGCGGTTGCCCAGATAT
GGGGTGAAGCAGGACGATCG

Downstream 100 bases:

>100_bases
TCCGCCCGCGGCAATATTGCCAAGCGCCATTCAATTTGGTCACAATTCCGTTTAGAGTCGCGAACGACGTGATCGGCGGC
AGCGGCAGCGAAAACGGGGC

Product: hemolysin III, novel hemolytic factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MANIPPQLEIPFVGRWHYSRAEMIADGIVHAVGIVLAIAAGSALLALAAFRVGPGEYIAAAFYVVSLLTVLSVSLAYNLW
PVSSPAKWVLRRFDHAAIYLLIAATYTPFLAQLDASPLARWMIVLVWIAAATGIAIKVCFPGRFDRLAIVFYLAIGWSGI
VLVKPLVETLPTTSIVLIVAGGVVYSCGVIFFAWKGLRFHNALWHGFVVTGAGLHLAAMVDCLVINRF

Sequences:

>Translated_228_residues
MANIPPQLEIPFVGRWHYSRAEMIADGIVHAVGIVLAIAAGSALLALAAFRVGPGEYIAAAFYVVSLLTVLSVSLAYNLW
PVSSPAKWVLRRFDHAAIYLLIAATYTPFLAQLDASPLARWMIVLVWIAAATGIAIKVCFPGRFDRLAIVFYLAIGWSGI
VLVKPLVETLPTTSIVLIVAGGVVYSCGVIFFAWKGLRFHNALWHGFVVTGAGLHLAAMVDCLVINRF
>Mature_227_residues
ANIPPQLEIPFVGRWHYSRAEMIADGIVHAVGIVLAIAAGSALLALAAFRVGPGEYIAAAFYVVSLLTVLSVSLAYNLWP
VSSPAKWVLRRFDHAAIYLLIAATYTPFLAQLDASPLARWMIVLVWIAAATGIAIKVCFPGRFDRLAIVFYLAIGWSGIV
LVKPLVETLPTTSIVLIVAGGVVYSCGVIFFAWKGLRFHNALWHGFVVTGAGLHLAAMVDCLVINRF

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI52630445, Length=216, Percent_Identity=31.4814814814815, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI154759275, Length=217, Percent_Identity=30.8755760368664, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI154759277, Length=241, Percent_Identity=28.6307053941909, Blast_Score=71, Evalue=8e-13,
Organism=Escherichia coli, GI1789266, Length=206, Percent_Identity=38.8349514563107, Blast_Score=131, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24640324, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 24664; Mature: 24532

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIPPQLEIPFVGRWHYSRAEMIADGIVHAVGIVLAIAAGSALLALAAFRVGPGEYIAA
CCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
AFYVVSLLTVLSVSLAYNLWPVSSPAKWVLRRFDHAAIYLLIAATYTPFLAQLDASPLAR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHH
WMIVLVWIAAATGIAIKVCFPGRFDRLAIVFYLAIGWSGIVLVKPLVETLPTTSIVLIVA
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEC
GGVVYSCGVIFFAWKGLRFHNALWHGFVVTGAGLHLAAMVDCLVINRF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANIPPQLEIPFVGRWHYSRAEMIADGIVHAVGIVLAIAAGSALLALAAFRVGPGEYIAA
CCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
AFYVVSLLTVLSVSLAYNLWPVSSPAKWVLRRFDHAAIYLLIAATYTPFLAQLDASPLAR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHH
WMIVLVWIAAATGIAIKVCFPGRFDRLAIVFYLAIGWSGIVLVKPLVETLPTTSIVLIVA
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEC
GGVVYSCGVIFFAWKGLRFHNALWHGFVVTGAGLHLAAMVDCLVINRF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]