Click here to switch to the map view.

The map label for this gene is efp1

Identifier: 13473354

GI number: 13473354

Start: 3144749

End: 3145315

Strand: Direct

Name: efp1

Synonym: mlr3919

Alternate gene names: 13473354

Gene position: 3144749-3145315 (Clockwise)

Preceding gene: 13473353

Following gene: 13473355

Centisome position: 44.69

GC content: 61.9

Gene sequence:

>567_bases
ATGGCCAAGATCAATGGCAACGAAATCCGTCCCGGCTACGTCATCGAGCATGATGGCGGCCTGTGGGTGGCGGTCAGGAC
CAACACCGTCAAGCCCGGCAAGGGCGGCGCCTACAACCAGGTCGAATTGAAGAATCTGATCAACGGCACCAAGCTCAACG
AGCGCTTCCGCTCGGCCGAGACGGTCGAGCAAATCCGCCTCGACCTGAAGGATTTTTCCTTCCTCTACGAGCAGGACGAC
GCGCTGGTGTTCATGGACACCCAGAGCTACGAACAGCTCGAACTGAACAAGGATTTCGTCGGCGACCGCGCCGCATTCCT
GCAGGACGGCATGATGGTGACGGTCCAGCTCTATGAGGAGAGGCCGATCGGCATCTCGCTGCCCGATCAGGTGACCCTGA
CCATCACCGAGGCCGACCCGGTGGTGAAGGGCCAGACGGCGGCGGCCTCCTACAAGCCGGCGGTGCTGAAGAACGGCATC
CGCGTGCTGGTGCCGCCTTTCATCGGCGCCGGCGAACGCATCATCGTCGACACCAACGAAATCACTTACGTGCGCCGCGC
CGACTGA

Upstream 100 bases:

>100_bases
GGGACCGATCGGGCGTCCCTTGCCTCTCCGGACGATTTGTGGTCTTGGGAGCCCCTAAATCGCCAGTCCCGGCGAAAATC
TCATTCCGGATCACCCCATC

Downstream 100 bases:

>100_bases
CGCGCTGCAGCAGGAAGACATACGATGGCACGCTCAGCCCTTCTCAACGTCATGGTCCAGGCCGCAATGAAGGCCGGCCG
CTCGCTGTCACGCGACTTTG

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 1

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAKINGNEIRPGYVIEHDGGLWVAVRTNTVKPGKGGAYNQVELKNLINGTKLNERFRSAETVEQIRLDLKDFSFLYEQDD
ALVFMDTQSYEQLELNKDFVGDRAAFLQDGMMVTVQLYEERPIGISLPDQVTLTITEADPVVKGQTAAASYKPAVLKNGI
RVLVPPFIGAGERIIVDTNEITYVRRAD

Sequences:

>Translated_188_residues
MAKINGNEIRPGYVIEHDGGLWVAVRTNTVKPGKGGAYNQVELKNLINGTKLNERFRSAETVEQIRLDLKDFSFLYEQDD
ALVFMDTQSYEQLELNKDFVGDRAAFLQDGMMVTVQLYEERPIGISLPDQVTLTITEADPVVKGQTAAASYKPAVLKNGI
RVLVPPFIGAGERIIVDTNEITYVRRAD
>Mature_187_residues
AKINGNEIRPGYVIEHDGGLWVAVRTNTVKPGKGGAYNQVELKNLINGTKLNERFRSAETVEQIRLDLKDFSFLYEQDDA
LVFMDTQSYEQLELNKDFVGDRAAFLQDGMMVTVQLYEERPIGISLPDQVTLTITEADPVVKGQTAAASYKPAVLKNGIR
VLVPPFIGAGERIIVDTNEITYVRRAD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=186, Percent_Identity=36.0215053763441, Blast_Score=119, Evalue=9e-29,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=29.9465240641711, Blast_Score=94, Evalue=6e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP1_RHILO (Q98F60)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104921.1
- ProteinModelPortal:   Q98F60
- SMR:   Q98F60
- GeneID:   1227582
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr3919
- NMPDR:   fig|266835.1.peg.3025
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20979; Mature: 20848

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKINGNEIRPGYVIEHDGGLWVAVRTNTVKPGKGGAYNQVELKNLINGTKLNERFRSAE
CCCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHHH
TVEQIRLDLKDFSFLYEQDDALVFMDTQSYEQLELNKDFVGDRAAFLQDGMMVTVQLYEE
HHHHHHHHHHHHEEEEECCCEEEEEECCCCEEEECCCCCCCCHHHHHHCCEEEEEEEECC
RPIGISLPDQVTLTITEADPVVKGQTAAASYKPAVLKNGIRVLVPPFIGAGERIIVDTNE
CCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCEEEEECCC
ITYVRRAD
EEEEEECC
>Mature Secondary Structure 
AKINGNEIRPGYVIEHDGGLWVAVRTNTVKPGKGGAYNQVELKNLINGTKLNERFRSAE
CCCCCCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCEEHHHHHCCCHHHHHHHHHH
TVEQIRLDLKDFSFLYEQDDALVFMDTQSYEQLELNKDFVGDRAAFLQDGMMVTVQLYEE
HHHHHHHHHHHHEEEEECCCEEEEEECCCCEEEECCCCCCCCHHHHHHCCEEEEEEEECC
RPIGISLPDQVTLTITEADPVVKGQTAAASYKPAVLKNGIRVLVPPFIGAGERIIVDTNE
CCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCEEEEECCC
ITYVRRAD
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968