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The map label for this gene is 13473224

Identifier: 13473224

GI number: 13473224

Start: 3023193

End: 3024221

Strand: Direct

Name: 13473224

Synonym: mlr3754

Alternate gene names: NA

Gene position: 3023193-3024221 (Clockwise)

Preceding gene: 13473223

Following gene: 13473225

Centisome position: 42.97

GC content: 64.92

Gene sequence:

>1029_bases
ATGATGAGCGAACGTCTCGAAGACATTGCCGCCGCGATCGTGGCCAACGGCAAGGGCCTGCTGGCCGCCGACGAAAGTTC
CGGCACCATCAAGAAGCGTTTCGACGTCATCGGCGTCGAATCGACCGCCGACAGCCGCCGCGACTATCGCGAGATGATGT
TCCGCGCCAGGGACGCGATGACCAAGTACATTTCCGGCGTCATCCTCTATGACGAGACCATCCGCCAGAAGGCCGCCGAC
GGCACGCCTCTGGTCGACATCATCAAGGCATCAGGCGCCATCCCCGGCATCAAGGTCGATGCCGGCGCCAAGCCGCTGGC
CGGCTTTCCCGGCGACACTGTCACCGAGGGCCTCGACGGCCTGCGCGAGCGGCTTGCCGACTATTACAAGCTCGGCGCCC
GCTTCGCCAAATGGCGCGCGGTGATCGACATCGACACCGGCAAGGGCGTGCCCTCGGCCAATTCGATCAACTCGAACACC
CACGCGCTCGCCCGCTATGCCGCCCTTTGCCAGGAAGCCGGCATCGTGCCGATCGTCGAGCCGGAAGTGCTGATGGACGG
CGCCCACGACATCGGCACCTGCTACGACGTCTCGAAGGCGACGCTGATCAAGCTTTATGATGAACTCCATGCGGCGCGCG
TCGTCCTCGAAGGCACGATCCTGAAGCCCAACATGGTGCTGTCGGGCAAGAAGTCGGGCACTGTGGACAGTCCCGAAAAG
GTCGCCGAGATGACCATAAAACTGTTCCGCGAGACGGTGCCGGCGGCGGTCCCGGGCATCGCCTTCCTCTCCGGCGGCCA
GGAGGACGAGGAGGCGACCGCCAACCTCAACGCCATCAACGCCATCGGCCCGCACCCGTGGAAGCTGACCTTCTCCTATG
GCCGCGCGCTGCAGGCCGCTCCACAGAAGGCATGGAGCGGCAAGGCGTCGAACGTCGCCGCCGGTCAGGCCGCCTTCACC
CATCGCGCCCACATGAACTATCTGGCGGCGCTCGGAAAATGGAAGGCAAGCCTCGAACAGGCCGCCTGA

Upstream 100 bases:

>100_bases
AAGAGGCGCCCGGGACTTTCAATCGATTCGAGCTTTCCGATGCCATTCCTTTGGCGGTAGATTTCCGTTAAGCGCGGAAC
GAACCCTTTTCAGGAGAAGC

Downstream 100 bases:

>100_bases
GCACAGCGCTTCCGTCATCGTTCAAACCCGGGCCAATGCGCCCGGGTTTTTGTTGTCTGCGATTTGGGGGAAGACCTCTT
CATCCCTATTTCCTCTGGGC

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MMSERLEDIAAAIVANGKGLLAADESSGTIKKRFDVIGVESTADSRRDYREMMFRARDAMTKYISGVILYDETIRQKAAD
GTPLVDIIKASGAIPGIKVDAGAKPLAGFPGDTVTEGLDGLRERLADYYKLGARFAKWRAVIDIDTGKGVPSANSINSNT
HALARYAALCQEAGIVPIVEPEVLMDGAHDIGTCYDVSKATLIKLYDELHAARVVLEGTILKPNMVLSGKKSGTVDSPEK
VAEMTIKLFRETVPAAVPGIAFLSGGQEDEEATANLNAINAIGPHPWKLTFSYGRALQAAPQKAWSGKASNVAAGQAAFT
HRAHMNYLAALGKWKASLEQAA

Sequences:

>Translated_342_residues
MMSERLEDIAAAIVANGKGLLAADESSGTIKKRFDVIGVESTADSRRDYREMMFRARDAMTKYISGVILYDETIRQKAAD
GTPLVDIIKASGAIPGIKVDAGAKPLAGFPGDTVTEGLDGLRERLADYYKLGARFAKWRAVIDIDTGKGVPSANSINSNT
HALARYAALCQEAGIVPIVEPEVLMDGAHDIGTCYDVSKATLIKLYDELHAARVVLEGTILKPNMVLSGKKSGTVDSPEK
VAEMTIKLFRETVPAAVPGIAFLSGGQEDEEATANLNAINAIGPHPWKLTFSYGRALQAAPQKAWSGKASNVAAGQAAFT
HRAHMNYLAALGKWKASLEQAA
>Mature_342_residues
MMSERLEDIAAAIVANGKGLLAADESSGTIKKRFDVIGVESTADSRRDYREMMFRARDAMTKYISGVILYDETIRQKAAD
GTPLVDIIKASGAIPGIKVDAGAKPLAGFPGDTVTEGLDGLRERLADYYKLGARFAKWRAVIDIDTGKGVPSANSINSNT
HALARYAALCQEAGIVPIVEPEVLMDGAHDIGTCYDVSKATLIKLYDELHAARVVLEGTILKPNMVLSGKKSGTVDSPEK
VAEMTIKLFRETVPAAVPGIAFLSGGQEDEEATANLNAINAIGPHPWKLTFSYGRALQAAPQKAWSGKASNVAAGQAAFT
HRAHMNYLAALGKWKASLEQAA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=336, Percent_Identity=52.9761904761905, Blast_Score=336, Evalue=1e-92,
Organism=Homo sapiens, GI34577110, Length=336, Percent_Identity=52.9761904761905, Blast_Score=336, Evalue=1e-92,
Organism=Homo sapiens, GI4557305, Length=336, Percent_Identity=52.9761904761905, Blast_Score=336, Evalue=1e-92,
Organism=Homo sapiens, GI193794814, Length=336, Percent_Identity=52.9761904761905, Blast_Score=336, Evalue=1e-92,
Organism=Homo sapiens, GI4885063, Length=337, Percent_Identity=52.5222551928783, Blast_Score=336, Evalue=2e-92,
Organism=Homo sapiens, GI40354205, Length=332, Percent_Identity=50.9036144578313, Blast_Score=327, Evalue=7e-90,
Organism=Caenorhabditis elegans, GI25150450, Length=333, Percent_Identity=48.948948948949, Blast_Score=323, Evalue=6e-89,
Organism=Caenorhabditis elegans, GI71983985, Length=332, Percent_Identity=50, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI71983990, Length=238, Percent_Identity=46.6386554621849, Blast_Score=214, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24650282, Length=335, Percent_Identity=52.5373134328358, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24650280, Length=335, Percent_Identity=52.5373134328358, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24650278, Length=335, Percent_Identity=52.5373134328358, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI221459619, Length=337, Percent_Identity=52.2255192878338, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24650288, Length=337, Percent_Identity=52.2255192878338, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI45553577, Length=335, Percent_Identity=51.9402985074627, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24650304, Length=334, Percent_Identity=43.1137724550898, Blast_Score=284, Evalue=5e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36475; Mature: 36475

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSERLEDIAAAIVANGKGLLAADESSGTIKKRFDVIGVESTADSRRDYREMMFRARDAM
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEEECCCCHHHHHHHHHHHHHHHHHH
TKYISGVILYDETIRQKAADGTPLVDIIKASGAIPGIKVDAGAKPLAGFPGDTVTEGLDG
HHHHCCEEEEHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHH
LRERLADYYKLGARFAKWRAVIDIDTGKGVPSANSINSNTHALARYAALCQEAGIVPIVE
HHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEC
PEVLMDGAHDIGTCYDVSKATLIKLYDELHAARVVLEGTILKPNMVLSGKKSGTVDSPEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEECCCCCCCCCCHHH
VAEMTIKLFRETVPAAVPGIAFLSGGQEDEEATANLNAINAIGPHPWKLTFSYGRALQAA
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHCCCCEECCCCCCCEEEEEHHCCHHHHC
PQKAWSGKASNVAAGQAAFTHRAHMNYLAALGKWKASLEQAA
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMSERLEDIAAAIVANGKGLLAADESSGTIKKRFDVIGVESTADSRRDYREMMFRARDAM
CCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHEEEECCCCHHHHHHHHHHHHHHHHHH
TKYISGVILYDETIRQKAADGTPLVDIIKASGAIPGIKVDAGAKPLAGFPGDTVTEGLDG
HHHHCCEEEEHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHH
LRERLADYYKLGARFAKWRAVIDIDTGKGVPSANSINSNTHALARYAALCQEAGIVPIVE
HHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEC
PEVLMDGAHDIGTCYDVSKATLIKLYDELHAARVVLEGTILKPNMVLSGKKSGTVDSPEK
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEECCCCCCCCCCHHH
VAEMTIKLFRETVPAAVPGIAFLSGGQEDEEATANLNAINAIGPHPWKLTFSYGRALQAA
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHCCCCEECCCCCCCEEEEEHHCCHHHHC
PQKAWSGKASNVAAGQAAFTHRAHMNYLAALGKWKASLEQAA
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]