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The map label for this gene is ptsP [H]

Identifier: 13472971

GI number: 13472971

Start: 2772239

End: 2774509

Strand: Reverse

Name: ptsP [H]

Synonym: mll3436

Alternate gene names: 13472971

Gene position: 2774509-2772239 (Counterclockwise)

Preceding gene: 13472972

Following gene: 13472970

Centisome position: 39.43

GC content: 66.05

Gene sequence:

>2271_bases
ATGCGTGACCAGGCCAGTGGCCCGCGCGTTTTGCTGAAACGGCTCCGCGAGCTCATGCAAGAGCCGCTGGAGCCGCAGGA
GCGGCTTGACCGGATCGTGCGCGATATCGCTTCCAACATGGTCGCGGAAGTGTGCTCGCTCTATGTGCTGCGCGCCGATT
CGGTGCTCGAGCTCTATGCCACCGAGGGTCTGAACCCGAACGCTGTCCACCTGGCGCAGCTGCGGCTCGGGCAAGGCCTT
GTCGGGACCATCGCCGCCAGCGCGCGGCCGCTCAATCTTTCCAATGCGCAGGAACATCCGGCCTTCGCCTACCTGCCGGA
GACCGGGGAAGAGATCTACAATTCCTTCCTCGGCGTGCCGGTGCTCAGGGCAGGGCGCACGCTGGGCGTCCTGGTCGTGC
AGAACAAGACCATGCGCCATTATCGCGACGACGAGGTCGAGGCGCTGGAAACCACCGCCATGGTCATCGCCGAGATGATC
GCCACTGGCGATCTGGCGCGGCTGACGCGGCCGGGCCTCGAACTCGACCTGCGCCGGCCGGTCAGCTTCACCGGCCTGTC
CTTCAACGACGGCGTCGGGCTTGGCCATGTCGTGCTGCATGAGCCGCGCATCGTCGTCACCAATCTGTTCAACGAGGACA
GCGAGGAAGAGGTCCGCCGGCTCGAGACCTCGCTCGGCTCGCTGCGGCTCTCCATCGACGATATGCTGGAACGCCGCGAC
GTTGCCTTCGAGGGCGAGCATCGCCAGGTGCTGGAAGCCTACCGCATGTTCGCCAATGACCGTGGGTGGGTGCGCCGGCT
GGAAGAGGCCATCCGCAACGGCCTGACGGCCGAAGCGGCCGTGGAAAAGGTGCAGAGCGACATGCGCGCGCGCATGCTGC
ACATGACCGATCCCTATCTGCGCGAGCGGATGAGCGATTTCGACGACCTCGCCAACCGGCTCTTGCGCCAGCTGATGGGG
CGTGGGCCGGAAGATGTCGCGGCCTCGCTGCCGAAGGACGCCATCATCGTCGCCCGCTCGATGGGCGCGGCCGAGCTGCT
CGACTATCCCAGGGAGAAAATGCGCGGGCTGGTGCTCGAGGATGGCGCGGCCACCAGCCATGTCGTCATCGTCGCGCGCG
CCATGGGCATTCCGGTCGCGGGCCAGATGAAGGGCGCCGTTTCCATGGCGGAAAACGGCGATGCCATCATCGTTGACGGC
GAGGAGGGCGTGATCCATCTGCGGCCGCAGTCCGATCTCGAAGCCGCCTATGCCGAAAAGGTGCGGTTCCGTGCGCGCCG
GCAAGAGGTCTATCGCGAACTGCGCAAGAAGCCGTCGACGACCAGGGACGGCGTCCAGGTCGATCTGTTGATGAATGCCG
GGCTTGCCGTCGACCTGCCGCAGCTGGCCGAGGCGGGTGCGGCCGGCATCGGCCTGTTCCGCACCGAGCTGCAATTCATG
GTCGCCTCGACCTTCCCGCGCGCCGAGGCGCAGGAGAAACTCTATCGCGACGTGCTGGAGGCGGCGCGTGGCAAGCCCGT
CACCTTCCGCACCATCGATATCGGTGGCGACAAGGTGCTGCCCTACTTCAAGGGCGCCATCCAGGAAGAGAACCCGGCGC
TCGGCTGGCGGGCGATCCGGCTGACGCTCGACCGGCCGGGGCTGCTGCGCACCCAGATCCGCGCCCTGCTGAAGGCCAGT
GGCGGGCGCGAGCTCAAGCTGATGCTGCCGATGGTGACCGAACTCAGCGAGATTGCGCAAGCAAGAGAAATCATCGACCG
CGAGGTGCGGCATCTCTCGCGCTTCGCCCACCATCTGCCGACCAGCCTCAAATTGGGCGCGATGCTGGAAGTGCCGTCGC
TGCTGTTCCAGCTCGACGAATTGATGAAGGCGGTCGACTTCGTCTCGGTCGGTTCGAATGATCTGTTCCAGTTCGTCATG
GCGGTCGACCGCGGCAACACGCAACTGGCCAACCGCTTCGACACGCTGTCGGCGCCGTTCCTGCGCGTGCTCAAGCAGAT
CGCCGATGCAGGCATCCGCAACCACACGCCGGTGACGCTGTGCGGAGAACTCGCCGGCAAGCCGATCTCGGCGATGGCGC
TGATCGGTCTGGGCTTCCGTTCGATCTCGATGTCGCCGGCCTCGATCGGCCCGGTCAAGGCGATGCTGACGGAACTGCCG
CTGGATGAGCTGACGGCGTTCTTCGACGACAATCTGATGGCGCCGGCGCAGGGGCTGCCGATGCGGGCGCTGCTGCAGGC
CTTCGCCGACGACCGCTCGATTCCGTTGTAG

Upstream 100 bases:

>100_bases
CGGTCTGGATAAGCAGTAGCAAGACTGAATCAGTTGTTGCGCGCATGCCGGCAGCGGCGGAAACTGCGCCGGCAAGTGTT
TCATTGGAGAAGAAGCCGCG

Downstream 100 bases:

>100_bases
CGCCCCCATCATGGTCAATCTGCCCCGCGATCGTATGGATCAAGTCGTCAAGCGTTTCGAGATGCTCGAAGCGCAGATGT
CGGCCGGCCCGGCGCCGGAC

Product: phosphoenolpyruvate-protein phosphotransferase, PtsP

Products: NA

Alternate protein names: Enzyme I-Ntr; Phosphotransferase system, enzyme I [H]

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MRDQASGPRVLLKRLRELMQEPLEPQERLDRIVRDIASNMVAEVCSLYVLRADSVLELYATEGLNPNAVHLAQLRLGQGL
VGTIAASARPLNLSNAQEHPAFAYLPETGEEIYNSFLGVPVLRAGRTLGVLVVQNKTMRHYRDDEVEALETTAMVIAEMI
ATGDLARLTRPGLELDLRRPVSFTGLSFNDGVGLGHVVLHEPRIVVTNLFNEDSEEEVRRLETSLGSLRLSIDDMLERRD
VAFEGEHRQVLEAYRMFANDRGWVRRLEEAIRNGLTAEAAVEKVQSDMRARMLHMTDPYLRERMSDFDDLANRLLRQLMG
RGPEDVAASLPKDAIIVARSMGAAELLDYPREKMRGLVLEDGAATSHVVIVARAMGIPVAGQMKGAVSMAENGDAIIVDG
EEGVIHLRPQSDLEAAYAEKVRFRARRQEVYRELRKKPSTTRDGVQVDLLMNAGLAVDLPQLAEAGAAGIGLFRTELQFM
VASTFPRAEAQEKLYRDVLEAARGKPVTFRTIDIGGDKVLPYFKGAIQEENPALGWRAIRLTLDRPGLLRTQIRALLKAS
GGRELKLMLPMVTELSEIAQAREIIDREVRHLSRFAHHLPTSLKLGAMLEVPSLLFQLDELMKAVDFVSVGSNDLFQFVM
AVDRGNTQLANRFDTLSAPFLRVLKQIADAGIRNHTPVTLCGELAGKPISAMALIGLGFRSISMSPASIGPVKAMLTELP
LDELTAFFDDNLMAPAQGLPMRALLQAFADDRSIPL

Sequences:

>Translated_756_residues
MRDQASGPRVLLKRLRELMQEPLEPQERLDRIVRDIASNMVAEVCSLYVLRADSVLELYATEGLNPNAVHLAQLRLGQGL
VGTIAASARPLNLSNAQEHPAFAYLPETGEEIYNSFLGVPVLRAGRTLGVLVVQNKTMRHYRDDEVEALETTAMVIAEMI
ATGDLARLTRPGLELDLRRPVSFTGLSFNDGVGLGHVVLHEPRIVVTNLFNEDSEEEVRRLETSLGSLRLSIDDMLERRD
VAFEGEHRQVLEAYRMFANDRGWVRRLEEAIRNGLTAEAAVEKVQSDMRARMLHMTDPYLRERMSDFDDLANRLLRQLMG
RGPEDVAASLPKDAIIVARSMGAAELLDYPREKMRGLVLEDGAATSHVVIVARAMGIPVAGQMKGAVSMAENGDAIIVDG
EEGVIHLRPQSDLEAAYAEKVRFRARRQEVYRELRKKPSTTRDGVQVDLLMNAGLAVDLPQLAEAGAAGIGLFRTELQFM
VASTFPRAEAQEKLYRDVLEAARGKPVTFRTIDIGGDKVLPYFKGAIQEENPALGWRAIRLTLDRPGLLRTQIRALLKAS
GGRELKLMLPMVTELSEIAQAREIIDREVRHLSRFAHHLPTSLKLGAMLEVPSLLFQLDELMKAVDFVSVGSNDLFQFVM
AVDRGNTQLANRFDTLSAPFLRVLKQIADAGIRNHTPVTLCGELAGKPISAMALIGLGFRSISMSPASIGPVKAMLTELP
LDELTAFFDDNLMAPAQGLPMRALLQAFADDRSIPL
>Mature_756_residues
MRDQASGPRVLLKRLRELMQEPLEPQERLDRIVRDIASNMVAEVCSLYVLRADSVLELYATEGLNPNAVHLAQLRLGQGL
VGTIAASARPLNLSNAQEHPAFAYLPETGEEIYNSFLGVPVLRAGRTLGVLVVQNKTMRHYRDDEVEALETTAMVIAEMI
ATGDLARLTRPGLELDLRRPVSFTGLSFNDGVGLGHVVLHEPRIVVTNLFNEDSEEEVRRLETSLGSLRLSIDDMLERRD
VAFEGEHRQVLEAYRMFANDRGWVRRLEEAIRNGLTAEAAVEKVQSDMRARMLHMTDPYLRERMSDFDDLANRLLRQLMG
RGPEDVAASLPKDAIIVARSMGAAELLDYPREKMRGLVLEDGAATSHVVIVARAMGIPVAGQMKGAVSMAENGDAIIVDG
EEGVIHLRPQSDLEAAYAEKVRFRARRQEVYRELRKKPSTTRDGVQVDLLMNAGLAVDLPQLAEAGAAGIGLFRTELQFM
VASTFPRAEAQEKLYRDVLEAARGKPVTFRTIDIGGDKVLPYFKGAIQEENPALGWRAIRLTLDRPGLLRTQIRALLKAS
GGRELKLMLPMVTELSEIAQAREIIDREVRHLSRFAHHLPTSLKLGAMLEVPSLLFQLDELMKAVDFVSVGSNDLFQFVM
AVDRGNTQLANRFDTLSAPFLRVLKQIADAGIRNHTPVTLCGELAGKPISAMALIGLGFRSISMSPASIGPVKAMLTELP
LDELTAFFDDNLMAPAQGLPMRALLQAFADDRSIPL

Specific function: Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP)

COG id: COG3605

COG function: function code T; Signal transduction protein containing GAF and PtsI domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GAF domain [H]

Homologues:

Organism=Escherichia coli, GI1789193, Length=713, Percent_Identity=34.7826086956522, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1788756, Length=582, Percent_Identity=30.2405498281787, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI1788726, Length=559, Percent_Identity=33.2737030411449, Blast_Score=264, Evalue=2e-71,
Organism=Escherichia coli, GI48994992, Length=515, Percent_Identity=31.4563106796116, Blast_Score=250, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003018
- InterPro:   IPR008279
- InterPro:   IPR006318
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR008731
- InterPro:   IPR015813 [H]

Pfam domain/function: PF01590 GAF; PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF02896 PEP-utilizers_C [H]

EC number: =2.7.3.9 [H]

Molecular weight: Translated: 83634; Mature: 83634

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDQASGPRVLLKRLRELMQEPLEPQERLDRIVRDIASNMVAEVCSLYVLRADSVLELYA
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TEGLNPNAVHLAQLRLGQGLVGTIAASARPLNLSNAQEHPAFAYLPETGEEIYNSFLGVP
HCCCCCCCEEHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCH
VLRAGRTLGVLVVQNKTMRHYRDDEVEALETTAMVIAEMIATGDLARLTRPGLELDLRRP
HHHCCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEECCCC
VSFTGLSFNDGVGLGHVVLHEPRIVVTNLFNEDSEEEVRRLETSLGSLRLSIDDMLERRD
CEECCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHEEECHHHHHHHHC
VAFEGEHRQVLEAYRMFANDRGWVRRLEEAIRNGLTAEAAVEKVQSDMRARMLHMTDPYL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RERMSDFDDLANRLLRQLMGRGPEDVAASLPKDAIIVARSMGAAELLDYPREKMRGLVLE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHHCCHHHHCCEEEE
DGAATSHVVIVARAMGIPVAGQMKGAVSMAENGDAIIVDGEEGVIHLRPQSDLEAAYAEK
CCCCCCHHEEEEHHHCCCCCCCCCCCCEECCCCCEEEEECCCCEEEECCCHHHHHHHHHH
VRFRARRQEVYRELRKKPSTTRDGVQVDLLMNAGLAVDLPQLAEAGAAGIGLFRTELQFM
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHH
VASTFPRAEAQEKLYRDVLEAARGKPVTFRTIDIGGDKVLPYFKGAIQEENPALGWRAIR
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEECHHHHHHCCCCCCCCCEEEEE
LTLDRPGLLRTQIRALLKASGGRELKLMLPMVTELSEIAQAREIIDREVRHLSRFAHHLP
EEECCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSLKLGAMLEVPSLLFQLDELMKAVDFVSVGSNDLFQFVMAVDRGNTQLANRFDTLSAPF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHH
LRVLKQIADAGIRNHTPVTLCGELAGKPISAMALIGLGFRSISMSPASIGPVKAMLTELP
HHHHHHHHHCCCCCCCCCEEEHHHCCCCHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCC
LDELTAFFDDNLMAPAQGLPMRALLQAFADDRSIPL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRDQASGPRVLLKRLRELMQEPLEPQERLDRIVRDIASNMVAEVCSLYVLRADSVLELYA
CCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TEGLNPNAVHLAQLRLGQGLVGTIAASARPLNLSNAQEHPAFAYLPETGEEIYNSFLGVP
HCCCCCCCEEHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHCCCH
VLRAGRTLGVLVVQNKTMRHYRDDEVEALETTAMVIAEMIATGDLARLTRPGLELDLRRP
HHHCCCEEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEECCCC
VSFTGLSFNDGVGLGHVVLHEPRIVVTNLFNEDSEEEVRRLETSLGSLRLSIDDMLERRD
CEECCCCCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHEEECHHHHHHHHC
VAFEGEHRQVLEAYRMFANDRGWVRRLEEAIRNGLTAEAAVEKVQSDMRARMLHMTDPYL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHH
RERMSDFDDLANRLLRQLMGRGPEDVAASLPKDAIIVARSMGAAELLDYPREKMRGLVLE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEECCCCHHHHHHCCHHHHCCEEEE
DGAATSHVVIVARAMGIPVAGQMKGAVSMAENGDAIIVDGEEGVIHLRPQSDLEAAYAEK
CCCCCCHHEEEEHHHCCCCCCCCCCCCEECCCCCEEEEECCCCEEEECCCHHHHHHHHHH
VRFRARRQEVYRELRKKPSTTRDGVQVDLLMNAGLAVDLPQLAEAGAAGIGLFRTELQFM
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHH
VASTFPRAEAQEKLYRDVLEAARGKPVTFRTIDIGGDKVLPYFKGAIQEENPALGWRAIR
HHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEECHHHHHHCCCCCCCCCEEEEE
LTLDRPGLLRTQIRALLKASGGRELKLMLPMVTELSEIAQAREIIDREVRHLSRFAHHLP
EEECCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSLKLGAMLEVPSLLFQLDELMKAVDFVSVGSNDLFQFVMAVDRGNTQLANRFDTLSAPF
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHH
LRVLKQIADAGIRNHTPVTLCGELAGKPISAMALIGLGFRSISMSPASIGPVKAMLTELP
HHHHHHHHHCCCCCCCCCEEEHHHCCCCHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCC
LDELTAFFDDNLMAPAQGLPMRALLQAFADDRSIPL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 7896715; 8973315 [H]