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The map label for this gene is cat [H]

Identifier: 13472906

GI number: 13472906

Start: 2694078

End: 2694695

Strand: Direct

Name: cat [H]

Synonym: mlr3351

Alternate gene names: 13472906

Gene position: 2694078-2694695 (Clockwise)

Preceding gene: 13472905

Following gene: 13472907

Centisome position: 38.29

GC content: 65.86

Gene sequence:

>618_bases
ATGACCAGGAAATTGTCAGAGACGCCGCTGGTCCACCCGACGGCGGAGGTGCACAATTCGACGCTCGGCCGCTGGACCGA
GATCGCCGACCGCAGCCGGGTTTCGGAAAGCGAACTCGGCGACTATTCCTACATGATGCAGGATTGCTCTGTCTGGTGCG
CGACAATCGGCAAGTTTGCAAACATTGCCGCCTCGGTGCGCCTCAACGCCACCAACCACCCGACCTGGCGGCCGACGCTG
CACCACTTCACCTACCGCGCCTCGGACTATTGGGACGACGCCGAGCACGAGAGCGAATTCTTCGCCCAGCGCCGCGCCAA
GCGCGTCACCATCGGCCACGACACCTGGCTCGGTCACGGCTCGACCGTCCTGCCGGGAGTCACTGTCGGCGATGGCGCGG
CGGTTGGTGCCGGAGCGGTCGTCTCGAAGGATGTCGCGCCCTACACCATCGTCGCCGGCGTACCGGCCAAACCGATCCGC
GAGCGCTTCGACCGCCGCACCGCCGAACGCTACCAGGTGCTTGCCTGGTGGGACTGGGACCACGCGCGGCTGCGCGCGTC
GCTCGAGGATTTTCGCGAGCTGTCGGCAGAGGCATTCCTGGAGAAATACGGGGGATAG

Upstream 100 bases:

>100_bases
GCGTCGCCTTGCTCGGCATCTTCCACGATCATGATGTGCGCGAGGCGGTAGCCGACCGCATCATCGACGTCACCGCTTTT
GCTCCAGGAAAACTCGCCGC

Downstream 100 bases:

>100_bases
TTCCTCACATCATCGTAATCAGGGGGGGCCCGTTCATATCCCTGACACAGGACTCGGACAGGACGCCATCTCCCCCAAGG
AGATCGCCATGCTCGACACC

Product: acetyltransferase (virginiamycin, streptogramin A, chloramphenicol)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTRKLSETPLVHPTAEVHNSTLGRWTEIADRSRVSESELGDYSYMMQDCSVWCATIGKFANIAASVRLNATNHPTWRPTL
HHFTYRASDYWDDAEHESEFFAQRRAKRVTIGHDTWLGHGSTVLPGVTVGDGAAVGAGAVVSKDVAPYTIVAGVPAKPIR
ERFDRRTAERYQVLAWWDWDHARLRASLEDFRELSAEAFLEKYGG

Sequences:

>Translated_205_residues
MTRKLSETPLVHPTAEVHNSTLGRWTEIADRSRVSESELGDYSYMMQDCSVWCATIGKFANIAASVRLNATNHPTWRPTL
HHFTYRASDYWDDAEHESEFFAQRRAKRVTIGHDTWLGHGSTVLPGVTVGDGAAVGAGAVVSKDVAPYTIVAGVPAKPIR
ERFDRRTAERYQVLAWWDWDHARLRASLEDFRELSAEAFLEKYGG
>Mature_204_residues
TRKLSETPLVHPTAEVHNSTLGRWTEIADRSRVSESELGDYSYMMQDCSVWCATIGKFANIAASVRLNATNHPTWRPTLH
HFTYRASDYWDDAEHESEFFAQRRAKRVTIGHDTWLGHGSTVLPGVTVGDGAAVGAGAVVSKDVAPYTIVAGVPAKPIRE
RFDRRTAERYQVLAWWDWDHARLRASLEDFRELSAEAFLEKYGG

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=114, Percent_Identity=34.2105263157895, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 23094; Mature: 22963

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLSETPLVHPTAEVHNSTLGRWTEIADRSRVSESELGDYSYMMQDCSVWCATIGKFA
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHH
NIAASVRLNATNHPTWRPTLHHFTYRASDYWDDAEHESEFFAQRRAKRVTIGHDTWLGHG
HHHEEEEECCCCCCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCCC
STVLPGVTVGDGAAVGAGAVVSKDVAPYTIVAGVPAKPIRERFDRRTAERYQVLAWWDWD
CEECCCEEECCCCCCCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCH
HARLRASLEDFRELSAEAFLEKYGG
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRKLSETPLVHPTAEVHNSTLGRWTEIADRSRVSESELGDYSYMMQDCSVWCATIGKFA
CCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHH
NIAASVRLNATNHPTWRPTLHHFTYRASDYWDDAEHESEFFAQRRAKRVTIGHDTWLGHG
HHHEEEEECCCCCCCCCCHHHHEEECCCCCCCCCHHHHHHHHHHHHCEEECCCCCCCCCC
STVLPGVTVGDGAAVGAGAVVSKDVAPYTIVAGVPAKPIRERFDRRTAERYQVLAWWDWD
CEECCCEEECCCCCCCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCH
HARLRASLEDFRELSAEAFLEKYGG
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]