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The map label for this gene is tdk

Identifier: 13472449

GI number: 13472449

Start: 2206617

End: 2207228

Strand: Direct

Name: tdk

Synonym: mlr2747

Alternate gene names: 13472449

Gene position: 2206617-2207228 (Clockwise)

Preceding gene: 13472445

Following gene: 13472451

Centisome position: 31.36

GC content: 63.56

Gene sequence:

>612_bases
ATGGCCAAGCTCTACTTCAACTACGCAACGATGAATGCCGGCAAGACGACGATGCTCTTGCAGGCCTCGTATAATTATCG
CGAGCGCGGCATGACGACGATGCTGTTCGTCGCCGGCCACTACCGCAAGGGCGACAGCGGCCTGATCTCGTCGCGCATCG
GACTGGAGACCGAGGCGGAGATGTTCCGCGACGGCGACGATTTGTTCGCCCGCGTCGCCGAACATCACGACCATACGACG
GTGCATTGCGTCTTCGTCGACGAGGCGCAGTTCCTCGAGGAGGAGCAGGTCTGGCAATTGGCCCGCATCGCCGACCGGCT
GAACATCCCGGTCATGTGCTACGGCCTGCGCACCGATTTCCAGGGCAAGCTGTTTTCCGGCTCGCGCGCGCTGCTGGCGA
TCGCCGACGATCTGCGCGAGGTGCGCACCATCTGCCGCTGCGGCCGCAAGGCGACGATGGTCGTGCGCCTCGGCGCCGAT
GGCAAGGTGGCCCGCCAGGGCGAACAGGTGGCGATCGGCAAGGATGTCTATGTTTCGCTCTGCCGCCGTCACTGGGAAGA
AGAAATGGGCCGCGCCGCGCCCGACGATTTCATCGGCTTCATGAAATCCTGA

Upstream 100 bases:

>100_bases
TGTCACGCCGCTTATCTTTTTCAGCGGCGAGCCGGCTTTTTCAGGGGAATGCCGCGGCGGCCCCTCCCCGCTTTGGGCCA
AGTCGGCTTAAAAGAGCGGC

Downstream 100 bases:

>100_bases
CCATCTTGAGCGGCGATCCGCCTCAGGCCGCCGAGACACGCCTCAGCGGAAACCGCCAGCCCAGCCGGACACCGAGCGTC
GCCAAGGCGATCAGCGCCAT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MAKLYFNYATMNAGKTTMLLQASYNYRERGMTTMLFVAGHYRKGDSGLISSRIGLETEAEMFRDGDDLFARVAEHHDHTT
VHCVFVDEAQFLEEEQVWQLARIADRLNIPVMCYGLRTDFQGKLFSGSRALLAIADDLREVRTICRCGRKATMVVRLGAD
GKVARQGEQVAIGKDVYVSLCRRHWEEEMGRAAPDDFIGFMKS

Sequences:

>Translated_203_residues
MAKLYFNYATMNAGKTTMLLQASYNYRERGMTTMLFVAGHYRKGDSGLISSRIGLETEAEMFRDGDDLFARVAEHHDHTT
VHCVFVDEAQFLEEEQVWQLARIADRLNIPVMCYGLRTDFQGKLFSGSRALLAIADDLREVRTICRCGRKATMVVRLGAD
GKVARQGEQVAIGKDVYVSLCRRHWEEEMGRAAPDDFIGFMKS
>Mature_202_residues
AKLYFNYATMNAGKTTMLLQASYNYRERGMTTMLFVAGHYRKGDSGLISSRIGLETEAEMFRDGDDLFARVAEHHDHTTV
HCVFVDEAQFLEEEQVWQLARIADRLNIPVMCYGLRTDFQGKLFSGSRALLAIADDLREVRTICRCGRKATMVVRLGADG
KVARQGEQVAIGKDVYVSLCRRHWEEEMGRAAPDDFIGFMKS

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=52.1052631578947, Blast_Score=213, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KITH_RHILO (Q98HR4)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_104016.1
- ProteinModelPortal:   Q98HR4
- SMR:   Q98HR4
- GeneID:   1226677
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr2747
- NMPDR:   fig|266835.1.peg.2120
- HOGENOM:   HBG522108
- OMA:   FRYGAMN
- ProtClustDB:   PRK04296
- BRENDA:   2.7.1.21
- GO:   GO:0005737
- HAMAP:   MF_00124
- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634
- PANTHER:   PTHR11441
- PIRSF:   PIRSF035805

Pfam domain/function: PF00265 TK

EC number: =2.7.1.21

Molecular weight: Translated: 23032; Mature: 22900

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: ACT_SITE 88-88

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYFNYATMNAGKTTMLLQASYNYRERGMTTMLFVAGHYRKGDSGLISSRIGLETEAE
CCEEEEEEEEECCCCEEEEEEECCCHHHCCCEEEEEEEECCCCCCCCCCHHCCCCCHHHH
MFRDGDDLFARVAEHHDHTTVHCVFVDEAQFLEEEQVWQLARIADRLNIPVMCYGLRTDF
HHCCCHHHHHHHHHCCCCCEEEEEEECCHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCC
QGKLFSGSRALLAIADDLREVRTICRCGRKATMVVRLGADGKVARQGEQVAIGKDVYVSL
CCEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHH
CRRHWEEEMGRAAPDDFIGFMKS
HHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure 
AKLYFNYATMNAGKTTMLLQASYNYRERGMTTMLFVAGHYRKGDSGLISSRIGLETEAE
CEEEEEEEEECCCCEEEEEEECCCHHHCCCEEEEEEEECCCCCCCCCCHHCCCCCHHHH
MFRDGDDLFARVAEHHDHTTVHCVFVDEAQFLEEEQVWQLARIADRLNIPVMCYGLRTDF
HHCCCHHHHHHHHHCCCCCEEEEEEECCHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCC
QGKLFSGSRALLAIADDLREVRTICRCGRKATMVVRLGADGKVARQGEQVAIGKDVYVSL
CCEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEECHHHHHHH
CRRHWEEEMGRAAPDDFIGFMKS
HHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968