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The map label for this gene is dgdR [H]

Identifier: 13472451

GI number: 13472451

Start: 2208246

End: 2209103

Strand: Direct

Name: dgdR [H]

Synonym: mlr2751

Alternate gene names: 13472451

Gene position: 2208246-2209103 (Clockwise)

Preceding gene: 13472449

Following gene: 13472452

Centisome position: 31.38

GC content: 65.27

Gene sequence:

>858_bases
ATGGCTGCTCCGCTTGACCTCAATCTCTTGAAAACCTTCGTCGCCGTCGTCGAGAGCGGCAGCCTGTCCAATGCGGCACC
TCGGGTCGGCCGCAGCCAGTCGGCGGTCAGCATGCAGATGCAGCGGCTGGAGGAGATGGTGGGCAACCAGCTTCTGGTGC
GCGGACCGAGAACGGTTACCCCCAACGCCATCGGCGAGGATTTTCTCATCTATGCGCGCCGGCTGCTGAAGCTGTCGGAT
GAGGCCTGGGCGAGTGTCACGCGACCGAAGGAGACGGGCAGCGTGCGCCTTGGCGTGCCGGACGACTATGCCGCCTTCCT
TCTGCCACCTGTGCTATCGCGTTTTGCCGAGGACCACCCGCTGGTGACGGTGGAACTGATCTGCGAACAGTCGACCGCGC
TGGTGAAAACCCTGGCGGAAGGACGGCTCGACCTGGCGATCGTCACTCGCTTGCCGGACCAGCCGCTCGACGTCATCCGG
CTTGAGCGTTTCGTCTGGGTCGCCTCGCCGAACCATGTCGCCTGGCAGACCGATCCCTTGCCTGTCGCCCTGTTCGAGCC
CGGCTGTGCCGCCAGGATGAATGTCCTGCAGGCGCTTGGCGAAGCTGACCGGTCTTACCGTTGCACCTATTCCAGCGCCT
CCTTGCTTGGCCTGATCGCGGTCGTGCAGGCCGGACTCGCCGTCGCCGGTCTGGCGCAGCGCAGCGTACCGCCATCGCTG
CGCATCATCGGCGGCAATGAAGGGCTTCCCGTGCTGCCGGATCTCGAAATCGGCATCCTGCGCAACCCGCTGTCGAGCAC
GCCGGCGGTCGATCGGCTGCATGATTTCCTGCGCCGCGACCTCGCACAGCAAGCCTGA

Upstream 100 bases:

>100_bases
ATCGAAAATCCCCCAGACGGGCGAACCCATCTGGCCACCAGTATAGCTTTCAAACAAGCGAATAGATTTGGAGCAAGCTA
TTCGATATGCTGATAGCACC

Downstream 100 bases:

>100_bases
GATCATCGTCTCCGCACGGGATTGGGTGCGACCGGCCCCCACTCGCCACGGTGCAGCGTTTGTTAAGGCCTCGGCCCTAT
AAGGCCGTCAGCCAGAGCTC

Product: transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MAAPLDLNLLKTFVAVVESGSLSNAAPRVGRSQSAVSMQMQRLEEMVGNQLLVRGPRTVTPNAIGEDFLIYARRLLKLSD
EAWASVTRPKETGSVRLGVPDDYAAFLLPPVLSRFAEDHPLVTVELICEQSTALVKTLAEGRLDLAIVTRLPDQPLDVIR
LERFVWVASPNHVAWQTDPLPVALFEPGCAARMNVLQALGEADRSYRCTYSSASLLGLIAVVQAGLAVAGLAQRSVPPSL
RIIGGNEGLPVLPDLEIGILRNPLSSTPAVDRLHDFLRRDLAQQA

Sequences:

>Translated_285_residues
MAAPLDLNLLKTFVAVVESGSLSNAAPRVGRSQSAVSMQMQRLEEMVGNQLLVRGPRTVTPNAIGEDFLIYARRLLKLSD
EAWASVTRPKETGSVRLGVPDDYAAFLLPPVLSRFAEDHPLVTVELICEQSTALVKTLAEGRLDLAIVTRLPDQPLDVIR
LERFVWVASPNHVAWQTDPLPVALFEPGCAARMNVLQALGEADRSYRCTYSSASLLGLIAVVQAGLAVAGLAQRSVPPSL
RIIGGNEGLPVLPDLEIGILRNPLSSTPAVDRLHDFLRRDLAQQA
>Mature_284_residues
AAPLDLNLLKTFVAVVESGSLSNAAPRVGRSQSAVSMQMQRLEEMVGNQLLVRGPRTVTPNAIGEDFLIYARRLLKLSDE
AWASVTRPKETGSVRLGVPDDYAAFLLPPVLSRFAEDHPLVTVELICEQSTALVKTLAEGRLDLAIVTRLPDQPLDVIRL
ERFVWVASPNHVAWQTDPLPVALFEPGCAARMNVLQALGEADRSYRCTYSSASLLGLIAVVQAGLAVAGLAQRSVPPSLR
IIGGNEGLPVLPDLEIGILRNPLSSTPAVDRLHDFLRRDLAQQA

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=265, Percent_Identity=33.2075471698113, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787806, Length=237, Percent_Identity=27.4261603375527, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787601, Length=181, Percent_Identity=28.7292817679558, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787879, Length=260, Percent_Identity=28.4615384615385, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790208, Length=148, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787589, Length=238, Percent_Identity=27.7310924369748, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081904, Length=176, Percent_Identity=30.1136363636364, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367136, Length=152, Percent_Identity=32.2368421052632, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI145693105, Length=288, Percent_Identity=25, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788297, Length=147, Percent_Identity=29.9319727891156, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786401, Length=140, Percent_Identity=32.1428571428571, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=144, Percent_Identity=27.7777777777778, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI157672245, Length=144, Percent_Identity=30.5555555555556, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30867; Mature: 30736

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPLDLNLLKTFVAVVESGSLSNAAPRVGRSQSAVSMQMQRLEEMVGNQLLVRGPRTVT
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCC
PNAIGEDFLIYARRLLKLSDEAWASVTRPKETGSVRLGVPDDYAAFLLPPVLSRFAEDHP
CCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
LVTVELICEQSTALVKTLAEGRLDLAIVTRLPDQPLDVIRLERFVWVASPNHVAWQTDPL
EEEEEEECCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHEEEEECCCCEEEECCCC
PVALFEPGCAARMNVLQALGEADRSYRCTYSSASLLGLIAVVQAGLAVAGLAQRSVPPSL
EEEEECCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
RIIGGNEGLPVLPDLEIGILRNPLSSTPAVDRLHDFLRRDLAQQA
EEEECCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAPLDLNLLKTFVAVVESGSLSNAAPRVGRSQSAVSMQMQRLEEMVGNQLLVRGPRTVT
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCC
PNAIGEDFLIYARRLLKLSDEAWASVTRPKETGSVRLGVPDDYAAFLLPPVLSRFAEDHP
CCCCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCC
LVTVELICEQSTALVKTLAEGRLDLAIVTRLPDQPLDVIRLERFVWVASPNHVAWQTDPL
EEEEEEECCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHEEEEECCCCEEEECCCC
PVALFEPGCAARMNVLQALGEADRSYRCTYSSASLLGLIAVVQAGLAVAGLAQRSVPPSL
EEEEECCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
RIIGGNEGLPVLPDLEIGILRNPLSSTPAVDRLHDFLRRDLAQQA
EEEECCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]