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The map label for this gene is cobP [H]

Identifier: 13471360

GI number: 13471360

Start: 1099346

End: 1099861

Strand: Reverse

Name: cobP [H]

Synonym: mll1308

Alternate gene names: 13471360

Gene position: 1099861-1099346 (Counterclockwise)

Preceding gene: 13471361

Following gene: 13471359

Centisome position: 15.63

GC content: 67.05

Gene sequence:

>516_bases
TTGCCTGATCGCAACAAGCTGACCTTCATCATCGGCGGTGCGCGCTCCGGCAAGAGCGCGCATGCCGAAATCCTGGTGAC
GGCGTTGCCGTCGCCATGGACCTATATCGCTACCGCGCAAGCCTATGACGACGAGATGCGTGAGCGCATCGCGCTGCACC
GCTCGCGGCGCGGCGAGGGCTGGACGACCATCGACGCGCCGCTCGACCTTGCCGGCGCGCTCGAGGCATTGCCCGACAAC
CAGCCGGTGCTTGTCGACTGCCTGACGCTGTGGCTGACCAATCACATGCTGGCCGATCACGACGTCGCAGCCGCGTGCCG
GCGGCTGGCGGATGTGCTGTCACGACCACGCGGACCCTGGTTCGTGGTCTCCAACGAAGTCGGGCAAGGGATCGTGCCGG
ACAATGCCTTGGCGCGCCGGTTTCGCGATGACGCCGGCCGGCTCAACCAGCAGGTCGCGGCGATCGCCGATACGGTGCTG
CTGATGGTGGCGGGGCTGCCGCTCAAGGTGAGGTGA

Upstream 100 bases:

>100_bases
GTGACGCTGACCAATCTGGTGTTCTGGCTGGTGCTCGGCGCCGTCGTCGGCGTGGTGCGCGGACGCTTTACCGGCACGGC
GACCAGCCTGCGCGACAGCT

Downstream 100 bases:

>100_bases
CATGACCGACATCGACAATAAGGACGAAGAGCGCCATCGCGCCAAGATGGCCAAGCGCAAGGCGGTGCAGGATGCCGAGG
TGGCGAGCAAGACGGTCGAA

Product: cobinamide kinase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPDRNKLTFIIGGARSGKSAHAEILVTALPSPWTYIATAQAYDDEMRERIALHRSRRGEGWTTIDAPLDLAGALEALPDN
QPVLVDCLTLWLTNHMLADHDVAAACRRLADVLSRPRGPWFVVSNEVGQGIVPDNALARRFRDDAGRLNQQVAAIADTVL
LMVAGLPLKVR

Sequences:

>Translated_171_residues
MPDRNKLTFIIGGARSGKSAHAEILVTALPSPWTYIATAQAYDDEMRERIALHRSRRGEGWTTIDAPLDLAGALEALPDN
QPVLVDCLTLWLTNHMLADHDVAAACRRLADVLSRPRGPWFVVSNEVGQGIVPDNALARRFRDDAGRLNQQVAAIADTVL
LMVAGLPLKVR
>Mature_170_residues
PDRNKLTFIIGGARSGKSAHAEILVTALPSPWTYIATAQAYDDEMRERIALHRSRRGEGWTTIDAPLDLAGALEALPDNQ
PVLVDCLTLWLTNHMLADHDVAAACRRLADVLSRPRGPWFVVSNEVGQGIVPDNALARRFRDDAGRLNQQVAAIADTVLL
MVAGLPLKVR

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=40.3314917127072, Blast_Score=113, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18713; Mature: 18581

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDRNKLTFIIGGARSGKSAHAEILVTALPSPWTYIATAQAYDDEMRERIALHRSRRGEG
CCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCC
WTTIDAPLDLAGALEALPDNQPVLVDCLTLWLTNHMLADHDVAAACRRLADVLSRPRGPW
CEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCE
FVVSNEVGQGIVPDNALARRFRDDAGRLNQQVAAIADTVLLMVAGLPLKVR
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure 
PDRNKLTFIIGGARSGKSAHAEILVTALPSPWTYIATAQAYDDEMRERIALHRSRRGEG
CCCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCC
WTTIDAPLDLAGALEALPDNQPVLVDCLTLWLTNHMLADHDVAAACRRLADVLSRPRGPW
CEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCE
FVVSNEVGQGIVPDNALARRFRDDAGRLNQQVAAIADTVLLMVAGLPLKVR
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]