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The map label for this gene is cobO [H]

Identifier: 13471359

GI number: 13471359

Start: 1098730

End: 1099344

Strand: Reverse

Name: cobO [H]

Synonym: mll1306

Alternate gene names: 13471359

Gene position: 1099344-1098730 (Counterclockwise)

Preceding gene: 13471360

Following gene: 13471357

Centisome position: 15.62

GC content: 64.55

Gene sequence:

>615_bases
ATGACCGACATCGACAATAAGGACGAAGAGCGCCATCGCGCCAAGATGGCCAAGCGCAAGGCGGTGCAGGATGCCGAGGT
GGCGAGCAAGACGGTCGAAAAGGGGCTGCTGATCGTCAACACCGGTCCGGGCAAGGGCAAGACCACGGCTGCCTTCGGCC
TGGCGCTGCGGATGCTTGGCTATGGTAAGCGCGTCGGCGTCGTGCAGTTCATCAAGGGCAAGTGGCACACCGGCGAGAAG
GATGCGTTTTCTGCCTTTGGCGACCGCGTCGTCTGGCACGCGATGGGCGAGGGCTTCACCTGGGAGACGCAGGATCTGAA
GCGCGACATCGCCGCCGCCGAGGCCGCCTGGGCCAAGGCGCTCGAGTTGATCGCCGACCCCTCGATCAGCCTTGTCGTGC
TCGACGAACTCAACATCGCGCTGCGTTACGATTATCTCGATCTCGACAAGGTGGTCGCGGCGCTGAAGGCGCGCCGCGAG
GGCCTGCATATCGTCGTCACCGGCCGCAACGCCAAGCCGGCGCTGGTCGAGGCGGCCGATCTGGTCACCGAGATGGGCGT
GACCAAACACCACTTCTCGGCAGGCGTGAAGGCGCAGCAGGGGATCGAGTTCTAG

Upstream 100 bases:

>100_bases
CGGTTTCGCGATGACGCCGGCCGGCTCAACCAGCAGGTCGCGGCGATCGCCGATACGGTGCTGCTGATGGTGGCGGGGCT
GCCGCTCAAGGTGAGGTGAC

Downstream 100 bases:

>100_bases
AACGCAAGAACGGCGATGACCGAAACCACGGCGAACAACGCGATCAGCAGGTAGTCAGCGACGCGGTAGAGCGTCAGCGC
CCGCCTGATGTCGCCGCTGT

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTDIDNKDEERHRAKMAKRKAVQDAEVASKTVEKGLLIVNTGPGKGKTTAAFGLALRMLGYGKRVGVVQFIKGKWHTGEK
DAFSAFGDRVVWHAMGEGFTWETQDLKRDIAAAEAAWAKALELIADPSISLVVLDELNIALRYDYLDLDKVVAALKARRE
GLHIVVTGRNAKPALVEAADLVTEMGVTKHHFSAGVKAQQGIEF

Sequences:

>Translated_204_residues
MTDIDNKDEERHRAKMAKRKAVQDAEVASKTVEKGLLIVNTGPGKGKTTAAFGLALRMLGYGKRVGVVQFIKGKWHTGEK
DAFSAFGDRVVWHAMGEGFTWETQDLKRDIAAAEAAWAKALELIADPSISLVVLDELNIALRYDYLDLDKVVAALKARRE
GLHIVVTGRNAKPALVEAADLVTEMGVTKHHFSAGVKAQQGIEF
>Mature_203_residues
TDIDNKDEERHRAKMAKRKAVQDAEVASKTVEKGLLIVNTGPGKGKTTAAFGLALRMLGYGKRVGVVQFIKGKWHTGEKD
AFSAFGDRVVWHAMGEGFTWETQDLKRDIAAAEAAWAKALELIADPSISLVVLDELNIALRYDYLDLDKVVAALKARREG
LHIVVTGRNAKPALVEAADLVTEMGVTKHHFSAGVKAQQGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=196, Percent_Identity=46.4285714285714, Blast_Score=177, Evalue=6e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22297; Mature: 22166

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIDNKDEERHRAKMAKRKAVQDAEVASKTVEKGLLIVNTGPGKGKTTAAFGLALRMLG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHH
YGKRVGVVQFIKGKWHTGEKDAFSAFGDRVVWHAMGEGFTWETQDLKRDIAAAEAAWAKA
CCCCCCHHEEECCCCCCCCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LELIADPSISLVVLDELNIALRYDYLDLDKVVAALKARREGLHIVVTGRNAKPALVEAAD
HHHHCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
LVTEMGVTKHHFSAGVKAQQGIEF
HHHHHCCHHHHHHCCCCHHCCCCC
>Mature Secondary Structure 
TDIDNKDEERHRAKMAKRKAVQDAEVASKTVEKGLLIVNTGPGKGKTTAAFGLALRMLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHH
YGKRVGVVQFIKGKWHTGEKDAFSAFGDRVVWHAMGEGFTWETQDLKRDIAAAEAAWAKA
CCCCCCHHEEECCCCCCCCHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LELIADPSISLVVLDELNIALRYDYLDLDKVVAALKARREGLHIVVTGRNAKPALVEAAD
HHHHCCCCEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
LVTEMGVTKHHFSAGVKAQQGIEF
HHHHHCCHHHHHHCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]