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The map label for this gene is maiA [H]

Identifier: 13471223

GI number: 13471223

Start: 951385

End: 952035

Strand: Direct

Name: maiA [H]

Synonym: mlr1135

Alternate gene names: 13471223

Gene position: 951385-952035 (Clockwise)

Preceding gene: 13471222

Following gene: 13471224

Centisome position: 13.52

GC content: 62.67

Gene sequence:

>651_bases
ATGAGCGACATCGTCCTGCACAATTACTACCGTTCCTCCACCTCCTACCGGGTGCGCATCGCGCTGGAGATGAAGGGGCT
GAGCTATGACTATGTCCCGCATCATTTGCGCCATGGCGAACATCTGGAACCAGCCTATCTCGCGGTCAATCCGCAGGGGC
TGGTGCCGGCATTGGTGCTCGACGACGGCACGCTGTTGACGCAGTCGCTGGCGATCATCGAATATCTCGACGAGATCCAT
CCCGCGCCGCCGCTGCTGCCGAAGGACCCGCTTGGCCGGGCGCGCGTACGAATGCTGGCGCAGATGATCGCCTGCGACAT
CCACCCGGTGAACAATCTGCGCGTGCTGACCTCGCTGCGCACTTTGTTCGGCGCCGGCGACCAGGACATCACCAACTGGT
TCCGCCACTGGGTGAACGAAGGCTTCCAGCCGCTTGAAAAGATTCTGGCTTCCTCGCCTCAGACCGGAACATTCTGCCAC
GGCGAGGCGGCGGGGCTGGCCGATATCTGCCTGGCGGCACAGATCACCAGCAACGCCCGTTTCGGCGTCGACCTGACGCC
TTACCCGACGATCACCCGCATCAACGCCGCCTGCATGGCGCTGCCAGCCTTCCAGAAAGCCGCTCCGCAGAACCAGATGG
ATGCCGAATAG

Upstream 100 bases:

>100_bases
TCGGTGCCGTCAAGCCCGGCGAGACGATGACCGGCGGCGTCGACGGCATCGGCACGATCGAAGTCACGGTCGGCCAACCG
CAGTCGTGAACGACAAAGCC

Downstream 100 bases:

>100_bases
GCTTCGTTGGTCCGCGCCGCATCCAGAGCAGCATGTCCGGCGGAATCGATTTCCGCTTGACCAGACAGGGAATCGGCTAT
CGTTTCCGGCAATGCGTGCC

Product: glutathione S-transferase

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSDIVLHNYYRSSTSYRVRIALEMKGLSYDYVPHHLRHGEHLEPAYLAVNPQGLVPALVLDDGTLLTQSLAIIEYLDEIH
PAPPLLPKDPLGRARVRMLAQMIACDIHPVNNLRVLTSLRTLFGAGDQDITNWFRHWVNEGFQPLEKILASSPQTGTFCH
GEAAGLADICLAAQITSNARFGVDLTPYPTITRINAACMALPAFQKAAPQNQMDAE

Sequences:

>Translated_216_residues
MSDIVLHNYYRSSTSYRVRIALEMKGLSYDYVPHHLRHGEHLEPAYLAVNPQGLVPALVLDDGTLLTQSLAIIEYLDEIH
PAPPLLPKDPLGRARVRMLAQMIACDIHPVNNLRVLTSLRTLFGAGDQDITNWFRHWVNEGFQPLEKILASSPQTGTFCH
GEAAGLADICLAAQITSNARFGVDLTPYPTITRINAACMALPAFQKAAPQNQMDAE
>Mature_215_residues
SDIVLHNYYRSSTSYRVRIALEMKGLSYDYVPHHLRHGEHLEPAYLAVNPQGLVPALVLDDGTLLTQSLAIIEYLDEIHP
APPLLPKDPLGRARVRMLAQMIACDIHPVNNLRVLTSLRTLFGAGDQDITNWFRHWVNEGFQPLEKILASSPQTGTFCHG
EAAGLADICLAAQITSNARFGVDLTPYPTITRINAACMALPAFQKAAPQNQMDAE

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=212, Percent_Identity=44.3396226415094, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI22202622, Length=161, Percent_Identity=44.7204968944099, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI194440732, Length=212, Percent_Identity=33.0188679245283, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551302, Length=211, Percent_Identity=42.1800947867299, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17556142, Length=214, Percent_Identity=42.9906542056075, Blast_Score=145, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17510461, Length=217, Percent_Identity=40.5529953917051, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322968, Length=87, Percent_Identity=43.6781609195402, Blast_Score=68, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21355857, Length=214, Percent_Identity=40.6542056074766, Blast_Score=163, Evalue=6e-41,
Organism=Drosophila melanogaster, GI45553325, Length=217, Percent_Identity=41.4746543778802, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21355859, Length=218, Percent_Identity=42.2018348623853, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24645375, Length=213, Percent_Identity=41.7840375586854, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI17933730, Length=201, Percent_Identity=26.865671641791, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922526, Length=211, Percent_Identity=29.3838862559242, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 23897; Mature: 23766

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIVLHNYYRSSTSYRVRIALEMKGLSYDYVPHHLRHGEHLEPAYLAVNPQGLVPALVL
CCCEEEEHEECCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEE
DDGTLLTQSLAIIEYLDEIHPAPPLLPKDPLGRARVRMLAQMIACDIHPVNNLRVLTSLR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TLFGAGDQDITNWFRHWVNEGFQPLEKILASSPQTGTFCHGEAAGLADICLAAQITSNAR
HHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHCCCCC
FGVDLTPYPTITRINAACMALPAFQKAAPQNQMDAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDIVLHNYYRSSTSYRVRIALEMKGLSYDYVPHHLRHGEHLEPAYLAVNPQGLVPALVL
CCEEEEHEECCCCCEEEEEEEEECCCCCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEE
DDGTLLTQSLAIIEYLDEIHPAPPLLPKDPLGRARVRMLAQMIACDIHPVNNLRVLTSLR
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
TLFGAGDQDITNWFRHWVNEGFQPLEKILASSPQTGTFCHGEAAGLADICLAAQITSNAR
HHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHCCCCC
FGVDLTPYPTITRINAACMALPAFQKAAPQNQMDAE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]