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The map label for this gene is dacC [H]

Identifier: 13470655

GI number: 13470655

Start: 307339

End: 308505

Strand: Reverse

Name: dacC [H]

Synonym: mll0426

Alternate gene names: 13470655

Gene position: 308505-307339 (Counterclockwise)

Preceding gene: 13470656

Following gene: 13470654

Centisome position: 4.38

GC content: 63.67

Gene sequence:

>1167_bases
ATGCAGTTGCGCGCCTTTCCGCCATTTGCCGGCCTTCTGGGACTGGCTTTGCTGCTGCTTTGCCTCGCTCCAGCACACGC
GCAGCTTTTCGAGACCAAGGCCACACAGGCCTTCATGATCGATGCCGACACCGGCACGGTGCTGTTCTCGAAAGACGCCG
ACAAGCCGATCCCACCGGCCTCGATGGCCAAGCTGATGACCATGGAGGTGGTTTTCAACGCCATCAAGTCCGGGCGCCTC
AAGCTCGACGACACATTCGTGGTCAGTGAAAACGCCTGGCGCAAGGGCGGGGCGCCATCGGGCACATCGACGATGTTCGC
CAAGCTCAAATCGGCGATCCGGCTTGAGGACCTGATCCAGGGCGTGACCGTGCAGGCGGCCAATGACGGCTGCATTGTCA
TCGCAGAAGGCATGGCCGGATCCGAGGACAATTTTGCCGCGCAGATGACCGAGCGCGCCCGCCAGATCGGGCTGAAAACA
TCGACCTTCGTCAATTCGACCGGCCTGCCGGCCGACGGCCAGCAGACAACGGTGCGCGAGCTGGCGCAGTTGGCCCTGCA
TTTGTGGCGCGATTATCCGGATTTCTATCGCTACTACGGGCTGAAGGATTTCACCTGGAACAAGATCTCGCAGAAGAACC
GCAACCCGCTGCTGGCCATGGACATCGGCGCCGACGGTCTGGCTGTCGGCGCGAGCGAGGTGGCCGGCTTCGGCATCGTC
GCTTCGGTCAGTCACAACGGCACGCGGGTGATCATGGCCATGAACGGGTTGGCCAACGACAAGGAGCGTGCCGAGGAGGC
GCGCAAGCTGCTCGACTGGGGCGCGCGCTCGTTCGAGAAGACCGAGATCTTCGCCAAGGACGAGGTGGTCGGCGAGGCCC
AGGTTTTTGGCGGTGCGAAATCCGGCGTGACGCTGAAGGCAAAAGGGCCGATCGACATCTTCCTGCCGATCACCAACCGC
GACAAGCTGACGGCCAGGATCGTCTACACCGGCCCGGTTGCGGCGCCCGTGGAGGAAGGCCAGCCGGTGGGTGCGCTGCG
CGTCTGGATCGGCGACACGCTGAGCCAGGAGACGCCGCTTTTCGCTGCCGAATCGATCGGCGTCGGCACATTGCCGCAGC
GCGCGCTCGATGCCGTCAAGGAACTGGCGATCGGCTGGCTGCGATAG

Upstream 100 bases:

>100_bases
TGGCTGTGCGCAACTGATCTATTTTGACCGGGCGGTTGATCCGGCGGAAAAAACCCTGATAGCTTGGCTGTGCCAAAACC
GGCAAACGGGTCGAGATTTC

Downstream 100 bases:

>100_bases
CACCGACGGCATGGACGTTTTCCCGAACGCGGACTATCTAGAGCCCAACAATCCACATGGACAAAGGCCCTTTCGTTTGG
CGCGCGGATTTTTCATCACC

Product: penicillin binding protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MQLRAFPPFAGLLGLALLLLCLAPAHAQLFETKATQAFMIDADTGTVLFSKDADKPIPPASMAKLMTMEVVFNAIKSGRL
KLDDTFVVSENAWRKGGAPSGTSTMFAKLKSAIRLEDLIQGVTVQAANDGCIVIAEGMAGSEDNFAAQMTERARQIGLKT
STFVNSTGLPADGQQTTVRELAQLALHLWRDYPDFYRYYGLKDFTWNKISQKNRNPLLAMDIGADGLAVGASEVAGFGIV
ASVSHNGTRVIMAMNGLANDKERAEEARKLLDWGARSFEKTEIFAKDEVVGEAQVFGGAKSGVTLKAKGPIDIFLPITNR
DKLTARIVYTGPVAAPVEEGQPVGALRVWIGDTLSQETPLFAAESIGVGTLPQRALDAVKELAIGWLR

Sequences:

>Translated_388_residues
MQLRAFPPFAGLLGLALLLLCLAPAHAQLFETKATQAFMIDADTGTVLFSKDADKPIPPASMAKLMTMEVVFNAIKSGRL
KLDDTFVVSENAWRKGGAPSGTSTMFAKLKSAIRLEDLIQGVTVQAANDGCIVIAEGMAGSEDNFAAQMTERARQIGLKT
STFVNSTGLPADGQQTTVRELAQLALHLWRDYPDFYRYYGLKDFTWNKISQKNRNPLLAMDIGADGLAVGASEVAGFGIV
ASVSHNGTRVIMAMNGLANDKERAEEARKLLDWGARSFEKTEIFAKDEVVGEAQVFGGAKSGVTLKAKGPIDIFLPITNR
DKLTARIVYTGPVAAPVEEGQPVGALRVWIGDTLSQETPLFAAESIGVGTLPQRALDAVKELAIGWLR
>Mature_388_residues
MQLRAFPPFAGLLGLALLLLCLAPAHAQLFETKATQAFMIDADTGTVLFSKDADKPIPPASMAKLMTMEVVFNAIKSGRL
KLDDTFVVSENAWRKGGAPSGTSTMFAKLKSAIRLEDLIQGVTVQAANDGCIVIAEGMAGSEDNFAAQMTERARQIGLKT
STFVNSTGLPADGQQTTVRELAQLALHLWRDYPDFYRYYGLKDFTWNKISQKNRNPLLAMDIGADGLAVGASEVAGFGIV
ASVSHNGTRVIMAMNGLANDKERAEEARKLLDWGARSFEKTEIFAKDEVVGEAQVFGGAKSGVTLKAKGPIDIFLPITNR
DKLTARIVYTGPVAAPVEEGQPVGALRVWIGDTLSQETPLFAAESIGVGTLPQRALDAVKELAIGWLR

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=378, Percent_Identity=34.6560846560847, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI87082022, Length=363, Percent_Identity=33.0578512396694, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786851, Length=390, Percent_Identity=30.7692307692308, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41718; Mature: 41718

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRAFPPFAGLLGLALLLLCLAPAHAQLFETKATQAFMIDADTGTVLFSKDADKPIPPA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCHH
SMAKLMTMEVVFNAIKSGRLKLDDTFVVSENAWRKGGAPSGTSTMFAKLKSAIRLEDLIQ
HHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GVTVQAANDGCIVIAEGMAGSEDNFAAQMTERARQIGLKTSTFVNSTGLPADGQQTTVRE
CCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCHHHHHH
LAQLALHLWRDYPDFYRYYGLKDFTWNKISQKNRNPLLAMDIGADGLAVGASEVAGFGIV
HHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHCCCCCEEEEEECCCCCEECHHHHCCCEEE
ASVSHNGTRVIMAMNGLANDKERAEEARKLLDWGARSFEKTEIFAKDEVVGEAQVFGGAK
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHEEEHHHHCCHHHHCCCCC
SGVTLKAKGPIDIFLPITNRDKLTARIVYTGPVAAPVEEGQPVGALRVWIGDTLSQETPL
CCEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCC
FAAESIGVGTLPQRALDAVKELAIGWLR
EEECCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLRAFPPFAGLLGLALLLLCLAPAHAQLFETKATQAFMIDADTGTVLFSKDADKPIPPA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCHH
SMAKLMTMEVVFNAIKSGRLKLDDTFVVSENAWRKGGAPSGTSTMFAKLKSAIRLEDLIQ
HHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GVTVQAANDGCIVIAEGMAGSEDNFAAQMTERARQIGLKTSTFVNSTGLPADGQQTTVRE
CCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHEECCCCCCCCCCHHHHHH
LAQLALHLWRDYPDFYRYYGLKDFTWNKISQKNRNPLLAMDIGADGLAVGASEVAGFGIV
HHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHCCCCCEEEEEECCCCCEECHHHHCCCEEE
ASVSHNGTRVIMAMNGLANDKERAEEARKLLDWGARSFEKTEIFAKDEVVGEAQVFGGAK
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHEEEHHHHCCHHHHCCCCC
SGVTLKAKGPIDIFLPITNRDKLTARIVYTGPVAAPVEEGQPVGALRVWIGDTLSQETPL
CCEEEEECCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCC
FAAESIGVGTLPQRALDAVKELAIGWLR
EEECCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]