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The map label for this gene is yabD [H]

Identifier: 13470649

GI number: 13470649

Start: 300887

End: 301681

Strand: Reverse

Name: yabD [H]

Synonym: mll0418

Alternate gene names: 13470649

Gene position: 301681-300887 (Counterclockwise)

Preceding gene: 13470650

Following gene: 13470648

Centisome position: 4.29

GC content: 62.89

Gene sequence:

>795_bases
ATGCTCGTCGACAGCCATTGCCATCTGGACTTTCCGGATTTCGCCGAAGAGCGGGCGGCCATTGTCGCCCGCGCCAAAGC
GGCTGGTATCGGCCGCATGGTGACGATATCAACCCGCGTGAAGCGCTTTCCACAAATGCTTGAAATTGCTGAGACTTTCG
ACGAAGTCTACTGCTCTGTCGGGACCCACCCGCACAATGCCGCGGAAGAACTCGACGTCACCACTGCCGAGCTCGTCCGT
CTGTCGGCACACCCGAAGGTGGTGGCAATCGGTGAAGCGGGGCTCGATTATTTCTACGACAAGGCGCCGCGCGACGCCCA
GGCGCTGGGTTTTCGCAATCACATTGCCGCCGCTCGCGCGACCGGGCTGCCGCTCGTCATCCATTCGCGCGACGCCGATG
ACGACATGGCAGCCATTCTCGAGGACGAAACAGGGAAGGGCGCCTTCCCCTTCATCCTGCATTGTTTCTCGTCCGGACGC
CGGCTGGCCGAGGTGGGCGTCTCGCTCGGCGGCTATGTGTCGTTCTCGGGCATACTGACCTTCAAGAACTCAGCCGAACT
GCGCGCCGTCGCCGCCGACGTGCCGCATGACCGGCTGCTCGTCGAAACCGACGCACCCTATCTGGCGCCGATTCCGTTCC
GGGGCAAGCGCAATGAGCCGGCCTACGTCGCGCATACCGCCAAGGTGCTGGCGGAGACGGTTGGCGTCAGCGAAGCTGAA
ATCGCGGATCTGACGACAAGCAACTTCTTCCGCCTGTTCGGCAAGATGCCGCGACCTGCCGAACTGAGCGCCTGA

Upstream 100 bases:

>100_bases
TGCATGTCCACGCCGACTATGCGTTGGTTCCTGGCACTGCGTTGCCCGCGCCGGAGGGCGTGTTTCCGCGTTATGTCGAA
CAGCCGGGTGCGAACGCCTG

Downstream 100 bases:

>100_bases
ACGATGACCGGCCGGCTGCGCCTCACCATTCTCGGCTGCGGCTCGTCGCCAGGTACGCCGCGCATCACCGGCGACTGGGG
CAATTGCGACCCGGCCAACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLVDSHCHLDFPDFAEERAAIVARAKAAGIGRMVTISTRVKRFPQMLEIAETFDEVYCSVGTHPHNAAEELDVTTAELVR
LSAHPKVVAIGEAGLDYFYDKAPRDAQALGFRNHIAAARATGLPLVIHSRDADDDMAAILEDETGKGAFPFILHCFSSGR
RLAEVGVSLGGYVSFSGILTFKNSAELRAVAADVPHDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAKVLAETVGVSEAE
IADLTTSNFFRLFGKMPRPAELSA

Sequences:

>Translated_264_residues
MLVDSHCHLDFPDFAEERAAIVARAKAAGIGRMVTISTRVKRFPQMLEIAETFDEVYCSVGTHPHNAAEELDVTTAELVR
LSAHPKVVAIGEAGLDYFYDKAPRDAQALGFRNHIAAARATGLPLVIHSRDADDDMAAILEDETGKGAFPFILHCFSSGR
RLAEVGVSLGGYVSFSGILTFKNSAELRAVAADVPHDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAKVLAETVGVSEAE
IADLTTSNFFRLFGKMPRPAELSA
>Mature_264_residues
MLVDSHCHLDFPDFAEERAAIVARAKAAGIGRMVTISTRVKRFPQMLEIAETFDEVYCSVGTHPHNAAEELDVTTAELVR
LSAHPKVVAIGEAGLDYFYDKAPRDAQALGFRNHIAAARATGLPLVIHSRDADDDMAAILEDETGKGAFPFILHCFSSGR
RLAEVGVSLGGYVSFSGILTFKNSAELRAVAADVPHDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAKVLAETVGVSEAE
IADLTTSNFFRLFGKMPRPAELSA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=272, Percent_Identity=28.6764705882353, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI110349734, Length=272, Percent_Identity=27.5735294117647, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI226061853, Length=278, Percent_Identity=29.136690647482, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=27.6264591439689, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI225903424, Length=223, Percent_Identity=29.5964125560538, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI14042943, Length=264, Percent_Identity=23.8636363636364, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI225903439, Length=238, Percent_Identity=25.2100840336134, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI226061595, Length=232, Percent_Identity=28.448275862069, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=43.1906614785992, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=33.2046332046332, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=31.5384615384615, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17559024, Length=279, Percent_Identity=29.0322580645161, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=26.7175572519084, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=227, Percent_Identity=30.8370044052863, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17543026, Length=298, Percent_Identity=24.496644295302, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=28.5211267605634, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24586117, Length=208, Percent_Identity=29.8076923076923, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221330018, Length=208, Percent_Identity=29.8076923076923, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28593; Mature: 28593

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLDFPDFAEERAAIVARAKAAGIGRMVTISTRVKRFPQMLEIAETFDEVYCSV
CEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
GTHPHNAAEELDVTTAELVRLSAHPKVVAIGEAGLDYFYDKAPRDAQALGFRNHIAAARA
CCCCCCCHHHHCCCHHHHHHHCCCCCEEEECCCCCHHHHCCCCCCHHHHCHHHHHHHHHH
TGLPLVIHSRDADDDMAAILEDETGKGAFPFILHCFSSGRRLAEVGVSLGGYVSFSGILT
CCCEEEEECCCCCCHHHHHEECCCCCCCHHHHHHHHHCCCEEHHHCCCCCCEEEEEEEEE
FKNSAELRAVAADVPHDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAKVLAETVGVSEAE
ECCCCCEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
IADLTTSNFFRLFGKMPRPAELSA
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLVDSHCHLDFPDFAEERAAIVARAKAAGIGRMVTISTRVKRFPQMLEIAETFDEVYCSV
CEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHC
GTHPHNAAEELDVTTAELVRLSAHPKVVAIGEAGLDYFYDKAPRDAQALGFRNHIAAARA
CCCCCCCHHHHCCCHHHHHHHCCCCCEEEECCCCCHHHHCCCCCCHHHHCHHHHHHHHHH
TGLPLVIHSRDADDDMAAILEDETGKGAFPFILHCFSSGRRLAEVGVSLGGYVSFSGILT
CCCEEEEECCCCCCHHHHHEECCCCCCCHHHHHHHHHCCCEEHHHCCCCCCEEEEEEEEE
FKNSAELRAVAADVPHDRLLVETDAPYLAPIPFRGKRNEPAYVAHTAKVLAETVGVSEAE
ECCCCCEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHH
IADLTTSNFFRLFGKMPRPAELSA
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]