Click here to switch to the map view.

The map label for this gene is lipB [H]

Identifier: 13470648

GI number: 13470648

Start: 300065

End: 300883

Strand: Reverse

Name: lipB [H]

Synonym: mll0416

Alternate gene names: 13470648

Gene position: 300883-300065 (Counterclockwise)

Preceding gene: 13470649

Following gene: 13470645

Centisome position: 4.28

GC content: 64.35

Gene sequence:

>819_bases
ATGACCGGCCGGCTGCGCCTCACCATTCTCGGCTGCGGCTCGTCGCCAGGTACGCCGCGCATCACCGGCGACTGGGGCAA
TTGCGACCCGGCCAACCCGAGGAACCGGCGCATGCGCACGGCAGCGCTGGTCGAGCGGGTTGCCGCCGATGGCGGCCGCA
CCACCGTGGTCATCGACACCGGGCCGGATTTCCGCGAACAGATGCTGCTTGCTTCGGTCAAACGCATCGATGCGGTCGTC
TACACGCACCCGCATGCCGACCATATCCACGGCATCGACGATCTGCGCGGCTATGTGCTGGAGCAGCGCCACCTGATCGA
CATCCATGCCGACCAGCCGACGATGCTGCGCCTGCGGCAGGCGTTCGGCTATTGCTTCGAGACGCCTCCGGGCAGTTCTT
ATCCGCCGATCGTGCGGGCGCATATCATCGACCACGCAAAGCCTGTCGTGATCGAAGGCGAGGGGGGTGCCCTCGCCCTC
GAACCCCTGCCGCAGATCCATGGCGACATCATTTCGCTCGGCTTCCGCATTGGCGGCCTGGCCTATTGCCCTGATATCAG
CGACTTTCCCGATCCCACCGCCGATCGGCTGCGCGGCCTGGAAATGCTGGTCATCGACGCGCTGCAGTACAACCCCCATC
CCAGCCATCTGTCACTCGGCCAGGCGCTCGGCTGGATCGAGAAGCTGGCGCCTAAACAGGCCGTGCTGACCCACATGCAC
GTGCCGCTCGACTATGCCAAGGTCAAGGGCGAAATGCCGGCCAACGTCACCCCGGCATACGATGGCATGGTGATTGAAAT
TCCTTATGAATCAGCGTGA

Upstream 100 bases:

>100_bases
GGTTGGCGTCAGCGAAGCTGAAATCGCGGATCTGACGACAAGCAACTTCTTCCGCCTGTTCGGCAAGATGCCGCGACCTG
CCGAACTGAGCGCCTGAACG

Downstream 100 bases:

>100_bases
TGCGAACGGCCTTTCATGAGGCTGTTCTGCTCGTCGGGCCGAGTATCAGCAGCGTTCCAGTCCGTTCATAGCCCATGCAG
GGATAAAGTAGAGCTCCGGC

Product: hydrolase

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTGRLRLTILGCGSSPGTPRITGDWGNCDPANPRNRRMRTAALVERVAADGGRTTVVIDTGPDFREQMLLASVKRIDAVV
YTHPHADHIHGIDDLRGYVLEQRHLIDIHADQPTMLRLRQAFGYCFETPPGSSYPPIVRAHIIDHAKPVVIEGEGGALAL
EPLPQIHGDIISLGFRIGGLAYCPDISDFPDPTADRLRGLEMLVIDALQYNPHPSHLSLGQALGWIEKLAPKQAVLTHMH
VPLDYAKVKGEMPANVTPAYDGMVIEIPYESA

Sequences:

>Translated_272_residues
MTGRLRLTILGCGSSPGTPRITGDWGNCDPANPRNRRMRTAALVERVAADGGRTTVVIDTGPDFREQMLLASVKRIDAVV
YTHPHADHIHGIDDLRGYVLEQRHLIDIHADQPTMLRLRQAFGYCFETPPGSSYPPIVRAHIIDHAKPVVIEGEGGALAL
EPLPQIHGDIISLGFRIGGLAYCPDISDFPDPTADRLRGLEMLVIDALQYNPHPSHLSLGQALGWIEKLAPKQAVLTHMH
VPLDYAKVKGEMPANVTPAYDGMVIEIPYESA
>Mature_271_residues
TGRLRLTILGCGSSPGTPRITGDWGNCDPANPRNRRMRTAALVERVAADGGRTTVVIDTGPDFREQMLLASVKRIDAVVY
THPHADHIHGIDDLRGYVLEQRHLIDIHADQPTMLRLRQAFGYCFETPPGSSYPPIVRAHIIDHAKPVVIEGEGGALALE
PLPQIHGDIISLGFRIGGLAYCPDISDFPDPTADRLRGLEMLVIDALQYNPHPSHLSLGQALGWIEKLAPKQAVLTHMHV
PLDYAKVKGEMPANVTPAYDGMVIEIPYESA

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 29777; Mature: 29645

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRLRLTILGCGSSPGTPRITGDWGNCDPANPRNRRMRTAALVERVAADGGRTTVVIDT
CCCEEEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
GPDFREQMLLASVKRIDAVVYTHPHADHIHGIDDLRGYVLEQRHLIDIHADQPTMLRLRQ
CCCHHHHHHHHHHHHHCEEEEECCCCHHCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHH
AFGYCFETPPGSSYPPIVRAHIIDHAKPVVIEGEGGALALEPLPQIHGDIISLGFRIGGL
HHCCEECCCCCCCCCCHHHEEECCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHCCE
AYCPDISDFPDPTADRLRGLEMLVIDALQYNPHPSHLSLGQALGWIEKLAPKQAVLTHMH
EECCCCCCCCCCHHHHHCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHC
VPLDYAKVKGEMPANVTPAYDGMVIEIPYESA
CCCHHHHHCCCCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
TGRLRLTILGCGSSPGTPRITGDWGNCDPANPRNRRMRTAALVERVAADGGRTTVVIDT
CCEEEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEC
GPDFREQMLLASVKRIDAVVYTHPHADHIHGIDDLRGYVLEQRHLIDIHADQPTMLRLRQ
CCCHHHHHHHHHHHHHCEEEEECCCCHHCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHH
AFGYCFETPPGSSYPPIVRAHIIDHAKPVVIEGEGGALALEPLPQIHGDIISLGFRIGGL
HHCCEECCCCCCCCCCHHHEEECCCCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHCCE
AYCPDISDFPDPTADRLRGLEMLVIDALQYNPHPSHLSLGQALGWIEKLAPKQAVLTHMH
EECCCCCCCCCCHHHHHCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHC
VPLDYAKVKGEMPANVTPAYDGMVIEIPYESA
CCCHHHHHCCCCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]