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The map label for this gene is torA

Identifier: 15603658

GI number: 15603658

Start: 2017902

End: 2020373

Strand: Direct

Name: torA

Synonym: PM1793

Alternate gene names: 15603658

Gene position: 2017902-2020373 (Clockwise)

Preceding gene: 15603657

Following gene: 15603659

Centisome position: 89.39

GC content: 43.89

Gene sequence:

>2472_bases
ATGAAACAATCACGTCGTCAATTTTTGAAAAATATGTCTGCCATGGCGGCGACATTTGCGATGCCTAATTTCCTTATTGC
TCAAAACGCGTTTGCACAGTCTGCAGAAAACGTCAGTGAATGGAAAATCACAGGTTCACACTGGGGGGCGATTCGTGCCA
AAGTGCAAAATGGCAAAGTTGTTGATGTCAAACCCTTTGAATATGACCAATATCCAACGGAAATGATCAAGGGGATCAAA
GACTTAATTTATAGCGAAGCACGTATTCGTTACCCAATGGTGCGTTTGGATTGGTTAAAAAAACGTCATAACAGCAATAC
GGCACAACGGGGTGATAACCGCTTTGTGCGTGTGACTTGGGATGAAGCATTAGATTTATTTTATGAAGAACTAGAACGTA
TCCAGCAAAATTACGGTCCATGGGCATTGCACACCGGTAACGTAGGGTGGCGATCTACCGGGCAATTCCATAGTTGCGGT
AACCATATGATCCGTGCTGTGGGGATGCACGGCAACAGTGTCAGTACCAGTGGGGATTATTCCACCGGTGCAGGACAGGT
GATTTTGCCTTATGTCTTAGGATCAACAGAGGTGTATTCACAAGGTACTTCTTGGGAAATTATTTTAAAAGAAAGTGAAA
ATATTATCTTCTGGGCAAGTGATCCAGTGAAAAACTTACAAGTGGGTTGGAACTGTGAAACTCACGAAGCCTATAAATAT
TTAGAACAATTAAAAGCAAAAGTAGCAGCAAAAGACGTGAATGTGATTTGCGTTGATCCCGTGAAAAGCAAAACCCAAAA
TTATTTAGGTTGCGACTTCCAATACATCAACCCGCAAACAGATGTTGCCTTTATGTTGGCGCTTGCCCACACCCTTTATG
TCGAGAATTTGTACGATAAAAAATTCATCGAGATGTACACCGTAGGTTTTGAAAAATTCTTGCCATATTTACTGGGTGAA
AGTGAAGATAAAGTGGTTAAAGATGCTGAGTGGGCAGCAAAAATTTGTGCTATTCAAGCAGAAGACATTCGTCAATTTGC
CAGAATGCTGGCAGGTAAACGTACCCAGTTGATTTTTGGTTGGGCAATCCAACGTCAACAACATGGCGAACAACCGTATT
GGATGGGTACCGTGCTGGCCGCCATGCTCGGGCAAATTGGTTTAGCGGGTGGTGGTATTAGCTATGCGCACCATTATAGC
TCGATTGGTATTCCAAGCTCGGGTGCCGCTATGCCGGGCGCCTTCCCATTAAACTTAGATGAAGGGCAAAAACCGAAATA
CGATAACAAAAATTACAACGGCTACAGTGCCGTAATCCCTTGCGCTAGAATAACGGATTCGCTATTGCAACCAGGCGAAA
CCATTGATCATAATGGACAGAAAATCACTTACGCCCCATATAAAATGGCGATCTTTACAGGTTGTAACCACTGGCACCGC
CATTCTGAACGTAACAAGATGAAACAGGCTTTCCAACGGTTAGAAACCATTGTGTCGATCAACTACAGCTGGACAGCCAC
TTGTCGCTTCTCGGATATTGTCTTACCCGCCTGTACCCCATTTGAGCGCAACGATATTGATGCTTATGGTTCGTACAGTA
ACCGTGGCGTGATCGCCATGCAAAAACTGGTAGATCCGTTGTATGACTCGCGTTCTGACTTTGAGATTTTCAAAGATCTT
TGCCGTCGTTTTGGTAAAGAAAAAGAATATTGTCGCAATATGGACGAAATGGAATGGGTCAAACACCTGTATGAAGCCTG
TCGGCAAGAAAACCAAGGCAAGTTTGACATGCCACCATTTGCTGAATTTTGGCAAAAGGGTTATGTATTATTCCCAGAAG
GGGAGCCTTGGGTACGTCATGCAGATTTCCGTGAGGATCCTGAATTACATGCGTTGGGCACACCGTCTGGCTTTATTGAA
ATTTTCAGTAACAAAATCGCCAGTTATGGCTATGCAGATTGTAAAGGTCATCCAATGTGGTTTGAAAAAGCTGAGCGTTC
GCATGGTGGACCAAAATCAGACAAATATCCGTTCTGGTTACAATCGGCACATCCTGATAAGCGCTTGCATTCCCAGTTAT
GCGAATCGAAAGCATTGCGTGAGACCTATGCCATTCAAGATCGTGAGCCTTTGTTTATCAATCCAGAAGATGCCAAACGT
TTAGGCATTGTTCATGGTGATTTAGTGCGGGTGTATAACGATCGGGGACAAGCGATTGTCGGTGCGCATGTGTCAGATAA
TTTCCCACAAGGTGTACTACGTTTACAAGAAGGTGCATGGTATTCACCTTTAGACGAAAAAGTCGGTTCTATTGATACCT
ATGGTGATCCGAATACCATGAGCTTAGATATTGGCAGTTCAAGTTTGGCGCAAGCGGTATCTGCCAATACTTGTTTGGTC
AATATTGAGAAATTTGTGGGACAAGCACCTGCGGTAACGGGTTTCCATGGTCCACATGAGGTCGCCCTATGA

Upstream 100 bases:

>100_bases
CCAACATGGATAAACAAACCAGTAAAGAAGTTTTACGCTATTTACAACTGCATTCATCTGACTTTGAAGCCCATTCTGAC
AGCAAGTAGGAGAGAACACC

Downstream 100 bases:

>100_bases
TGCCGTTTTCCCGTGAAGAACGCCAATTTGTCTATACTTGGCTGAGCAATATGCTTGGTCATGAGCTTTCCGCTAGCCAA
TTAGCGCAATATCAACAAGG

Product: TorA

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase

Number of amino acids: Translated: 823; Mature: 823

Protein sequence:

>823_residues
MKQSRRQFLKNMSAMAATFAMPNFLIAQNAFAQSAENVSEWKITGSHWGAIRAKVQNGKVVDVKPFEYDQYPTEMIKGIK
DLIYSEARIRYPMVRLDWLKKRHNSNTAQRGDNRFVRVTWDEALDLFYEELERIQQNYGPWALHTGNVGWRSTGQFHSCG
NHMIRAVGMHGNSVSTSGDYSTGAGQVILPYVLGSTEVYSQGTSWEIILKESENIIFWASDPVKNLQVGWNCETHEAYKY
LEQLKAKVAAKDVNVICVDPVKSKTQNYLGCDFQYINPQTDVAFMLALAHTLYVENLYDKKFIEMYTVGFEKFLPYLLGE
SEDKVVKDAEWAAKICAIQAEDIRQFARMLAGKRTQLIFGWAIQRQQHGEQPYWMGTVLAAMLGQIGLAGGGISYAHHYS
SIGIPSSGAAMPGAFPLNLDEGQKPKYDNKNYNGYSAVIPCARITDSLLQPGETIDHNGQKITYAPYKMAIFTGCNHWHR
HSERNKMKQAFQRLETIVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVIAMQKLVDPLYDSRSDFEIFKDL
CRRFGKEKEYCRNMDEMEWVKHLYEACRQENQGKFDMPPFAEFWQKGYVLFPEGEPWVRHADFREDPELHALGTPSGFIE
IFSNKIASYGYADCKGHPMWFEKAERSHGGPKSDKYPFWLQSAHPDKRLHSQLCESKALRETYAIQDREPLFINPEDAKR
LGIVHGDLVRVYNDRGQAIVGAHVSDNFPQGVLRLQEGAWYSPLDEKVGSIDTYGDPNTMSLDIGSSSLAQAVSANTCLV
NIEKFVGQAPAVTGFHGPHEVAL

Sequences:

>Translated_823_residues
MKQSRRQFLKNMSAMAATFAMPNFLIAQNAFAQSAENVSEWKITGSHWGAIRAKVQNGKVVDVKPFEYDQYPTEMIKGIK
DLIYSEARIRYPMVRLDWLKKRHNSNTAQRGDNRFVRVTWDEALDLFYEELERIQQNYGPWALHTGNVGWRSTGQFHSCG
NHMIRAVGMHGNSVSTSGDYSTGAGQVILPYVLGSTEVYSQGTSWEIILKESENIIFWASDPVKNLQVGWNCETHEAYKY
LEQLKAKVAAKDVNVICVDPVKSKTQNYLGCDFQYINPQTDVAFMLALAHTLYVENLYDKKFIEMYTVGFEKFLPYLLGE
SEDKVVKDAEWAAKICAIQAEDIRQFARMLAGKRTQLIFGWAIQRQQHGEQPYWMGTVLAAMLGQIGLAGGGISYAHHYS
SIGIPSSGAAMPGAFPLNLDEGQKPKYDNKNYNGYSAVIPCARITDSLLQPGETIDHNGQKITYAPYKMAIFTGCNHWHR
HSERNKMKQAFQRLETIVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVIAMQKLVDPLYDSRSDFEIFKDL
CRRFGKEKEYCRNMDEMEWVKHLYEACRQENQGKFDMPPFAEFWQKGYVLFPEGEPWVRHADFREDPELHALGTPSGFIE
IFSNKIASYGYADCKGHPMWFEKAERSHGGPKSDKYPFWLQSAHPDKRLHSQLCESKALRETYAIQDREPLFINPEDAKR
LGIVHGDLVRVYNDRGQAIVGAHVSDNFPQGVLRLQEGAWYSPLDEKVGSIDTYGDPNTMSLDIGSSSLAQAVSANTCLV
NIEKFVGQAPAVTGFHGPHEVAL
>Mature_823_residues
MKQSRRQFLKNMSAMAATFAMPNFLIAQNAFAQSAENVSEWKITGSHWGAIRAKVQNGKVVDVKPFEYDQYPTEMIKGIK
DLIYSEARIRYPMVRLDWLKKRHNSNTAQRGDNRFVRVTWDEALDLFYEELERIQQNYGPWALHTGNVGWRSTGQFHSCG
NHMIRAVGMHGNSVSTSGDYSTGAGQVILPYVLGSTEVYSQGTSWEIILKESENIIFWASDPVKNLQVGWNCETHEAYKY
LEQLKAKVAAKDVNVICVDPVKSKTQNYLGCDFQYINPQTDVAFMLALAHTLYVENLYDKKFIEMYTVGFEKFLPYLLGE
SEDKVVKDAEWAAKICAIQAEDIRQFARMLAGKRTQLIFGWAIQRQQHGEQPYWMGTVLAAMLGQIGLAGGGISYAHHYS
SIGIPSSGAAMPGAFPLNLDEGQKPKYDNKNYNGYSAVIPCARITDSLLQPGETIDHNGQKITYAPYKMAIFTGCNHWHR
HSERNKMKQAFQRLETIVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVIAMQKLVDPLYDSRSDFEIFKDL
CRRFGKEKEYCRNMDEMEWVKHLYEACRQENQGKFDMPPFAEFWQKGYVLFPEGEPWVRHADFREDPELHALGTPSGFIE
IFSNKIASYGYADCKGHPMWFEKAERSHGGPKSDKYPFWLQSAHPDKRLHSQLCESKALRETYAIQDREPLFINPEDAKR
LGIVHGDLVRVYNDRGQAIVGAHVSDNFPQGVLRLQEGAWYSPLDEKVGSIDTYGDPNTMSLDIGSSSLAQAVSANTCLV
NIEKFVGQAPAVTGFHGPHEVAL

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787231, Length=833, Percent_Identity=53.1812725090036, Blast_Score=901, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=828, Percent_Identity=38.4057971014493, Blast_Score=583, Evalue=1e-167,
Organism=Escherichia coli, GI145693196, Length=791, Percent_Identity=38.3059418457649, Blast_Score=566, Evalue=1e-162,
Organism=Escherichia coli, GI87081797, Length=760, Percent_Identity=27.7631578947368, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1787870, Length=862, Percent_Identity=26.2180974477958, Blast_Score=236, Evalue=6e-63,
Organism=Escherichia coli, GI171474008, Length=846, Percent_Identity=26.8321513002364, Blast_Score=235, Evalue=7e-63,
Organism=Escherichia coli, GI3868721, Length=749, Percent_Identity=23.2309746328438, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TORA_PASMU (Q9CK41)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_246732.1
- ProteinModelPortal:   Q9CK41
- SMR:   Q9CK41
- GeneID:   1245140
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM1793
- NMPDR:   fig|272843.1.peg.1794
- HOGENOM:   HBG304064
- OMA:   NAETHES
- ProtClustDB:   PRK15102
- BioCyc:   PMUL272843:PM1793-MONOMER
- BRENDA:   1.7.2.3
- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887
- Gene3D:   G3DSA:2.40.40.20
- TIGRFAMs:   TIGR00509
- TIGRFAMs:   TIGR01409
- TIGRFAMs:   TIGR02164

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: =1.7.2.3

Molecular weight: Translated: 93358; Mature: 93358

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1; PS00490 MOLYBDOPTERIN_PROK_2; PS00932 MOLYBDOPTERIN_PROK_3; PS51318 TAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSRRQFLKNMSAMAATFAMPNFLIAQNAFAQSAENVSEWKITGSHWGAIRAKVQNGKV
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHEEEECCCCCEEEEEECCCEE
VDVKPFEYDQYPTEMIKGIKDLIYSEARIRYPMVRLDWLKKRHNSNTAQRGDNRFVRVTW
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEH
DEALDLFYEELERIQQNYGPWALHTGNVGWRSTGQFHSCGNHMIRAVGMHGNSVSTSGDY
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCCC
STGAGQVILPYVLGSTEVYSQGTSWEIILKESENIIFWASDPVKNLQVGWNCETHEAYKY
CCCCCCEEEEEEECCCHHHCCCCCEEEEEECCCCEEEEECCCCCCCEECCCCCHHHHHHH
LEQLKAKVAAKDVNVICVDPVKSKTQNYLGCDFQYINPQTDVAFMLALAHTLYVENLYDK
HHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
KFIEMYTVGFEKFLPYLLGESEDKVVKDAEWAAKICAIQAEDIRQFARMLAGKRTQLIFG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
WAIQRQQHGEQPYWMGTVLAAMLGQIGLAGGGISYAHHYSSIGIPSSGAAMPGAFPLNLD
EEHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEECCCC
EGQKPKYDNKNYNGYSAVIPCARITDSLLQPGETIDHNGQKITYAPYKMAIFTGCNHWHR
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCHHHHH
HSERNKMKQAFQRLETIVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVIAM
HHHHHHHHHHHHHHHHHEECCCCEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCHHHH
QKLVDPLYDSRSDFEIFKDLCRRFGKEKEYCRNMDEMEWVKHLYEACRQENQGKFDMPPF
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
AEFWQKGYVLFPEGEPWVRHADFREDPELHALGTPSGFIEIFSNKIASYGYADCKGHPMW
HHHHHCCEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHH
FEKAERSHGGPKSDKYPFWLQSAHPDKRLHSQLCESKALRETYAIQDREPLFINPEDAKR
HHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHH
LGIVHGDLVRVYNDRGQAIVGAHVSDNFPQGVLRLQEGAWYSPLDEKVGSIDTYGDPNTM
CCCEECCEEEEECCCCCEEEEECCCCCCCHHHHEECCCCCCCCHHHHHCCCCCCCCCCEE
SLDIGSSSLAQAVSANTCLVNIEKFVGQAPAVTGFHGPHEVAL
EEECCCHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQSRRQFLKNMSAMAATFAMPNFLIAQNAFAQSAENVSEWKITGSHWGAIRAKVQNGKV
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHEEEECCCCCEEEEEECCCEE
VDVKPFEYDQYPTEMIKGIKDLIYSEARIRYPMVRLDWLKKRHNSNTAQRGDNRFVRVTW
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEH
DEALDLFYEELERIQQNYGPWALHTGNVGWRSTGQFHSCGNHMIRAVGMHGNSVSTSGDY
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCCC
STGAGQVILPYVLGSTEVYSQGTSWEIILKESENIIFWASDPVKNLQVGWNCETHEAYKY
CCCCCCEEEEEEECCCHHHCCCCCEEEEEECCCCEEEEECCCCCCCEECCCCCHHHHHHH
LEQLKAKVAAKDVNVICVDPVKSKTQNYLGCDFQYINPQTDVAFMLALAHTLYVENLYDK
HHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
KFIEMYTVGFEKFLPYLLGESEDKVVKDAEWAAKICAIQAEDIRQFARMLAGKRTQLIFG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEE
WAIQRQQHGEQPYWMGTVLAAMLGQIGLAGGGISYAHHYSSIGIPSSGAAMPGAFPLNLD
EEHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEECCCC
EGQKPKYDNKNYNGYSAVIPCARITDSLLQPGETIDHNGQKITYAPYKMAIFTGCNHWHR
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCHHHHH
HSERNKMKQAFQRLETIVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVIAM
HHHHHHHHHHHHHHHHHEECCCCEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCCHHHH
QKLVDPLYDSRSDFEIFKDLCRRFGKEKEYCRNMDEMEWVKHLYEACRQENQGKFDMPPF
HHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCH
AEFWQKGYVLFPEGEPWVRHADFREDPELHALGTPSGFIEIFSNKIASYGYADCKGHPMW
HHHHHCCEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHH
FEKAERSHGGPKSDKYPFWLQSAHPDKRLHSQLCESKALRETYAIQDREPLFINPEDAKR
HHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHH
LGIVHGDLVRVYNDRGQAIVGAHVSDNFPQGVLRLQEGAWYSPLDEKVGSIDTYGDPNTM
CCCEECCEEEEECCCCCEEEEECCCCCCCHHHHEECCCCCCCCHHHHHCCCCCCCCCCEE
SLDIGSSSLAQAVSANTCLVNIEKFVGQAPAVTGFHGPHEVAL
EEECCCHHHHHHHCCCEEEEEHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100