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The map label for this gene is torC [H]

Identifier: 15603657

GI number: 15603657

Start: 2016712

End: 2017890

Strand: Direct

Name: torC [H]

Synonym: PM1792

Alternate gene names: 15603657

Gene position: 2016712-2017890 (Clockwise)

Preceding gene: 15603656

Following gene: 15603658

Centisome position: 89.33

GC content: 42.49

Gene sequence:

>1179_bases
ATGAAATTTTTTATGTTAATTAAGCGATTTTTTACCAAGCCTTCTGCCAAAATAGGTTTGGGTATTTTAGTGAGTATTGG
CTTTATTGCAGGTGCGATTAGCTGGCAAAAATTTAATGATTTAATGGATCACACCAGTACTGAAGAATTTTGTATTGGTT
GTCATTCTATGCAGCAACCATTAGAAGAATTAAAGCAAACGGCACATTGGTCAAATCGTTCTGGTGTCACTGCCACTTGC
TCAAGCTGCCACTTGCCGCATGATAAAACCGCCAAATATGCCCGCAAAGTCCAAGCGGTGCGTGAGGTATTTGCGGAATT
CACCGGCAAATATGAGGAAGAAGGCGCCTTTGAAAAGCACCGCCAAGAAATGGCAGAACGAGAATGGGCTCGTTTTGCAG
CGAATGGTTCGAAAGAATGTAAAGCCTGTCATAGCTATGAGCGCATGAACTTCGACAAAATGTCTGAGGCAGCGAGAAAA
GCCATGATTCCTGCCGCAGCGAAAGATCAAAGCTGTATGGATTGCCATAAAGGCGTAGCACACCATTTACCAAAAACACA
AGTGAGTGAAGGCAGTACTTCGAAATTTGATCAATTTGTGGCAAAAGCACCACAGGCGGATAAAACGTATTACAGTAAAG
CCAATATCGCGCTGTTTAAAGATGAAGCTATGCAAGCGCAAATTGGTCAACTGGAAACGGCGGTACCAGTACGTTTTGTT
AAAGCAGGTCAAGGCGCGGATTTAGTGGAAATGACCATGTGGCGTAAAGACAAAGGTTTTGGTCGAATTTGGTATCACCA
ATTTGGCAAAAATATTACAGATGCCGTATTAAGCAAAGAATTTATGCAAAATGCACCGCACTTTACGGTGTTAGCGAAAC
AAGAAGATCCTTTAACAGGTTTAACGTGGCAACAAGTCAGCATGCAAGTGTGGATTGCTAAATCACAGTTAATTGAGGAC
GTGAAGCCAGTATGGGCAGCGGCGGAAAGCATGTACAAAACCCAATGTAGTACCTGTCATAGACAGCCAGAAGTGGCGCA
CTTTGACTCGAATACATGGATCGGTTTATTCAATGGTATGGTGGGTTTCACCAACATGGATAAACAAACCAGTAAAGAAG
TTTTACGCTATTTACAACTGCATTCATCTGACTTTGAAGCCCATTCTGACAGCAAGTAG

Upstream 100 bases:

>100_bases
TTGCCGATTTTAATGATGGGGAGCGTGGGAGCTTATGGCTTGATCGTTTGGTTATTACAAATGTTCGTCATTGGCTTACC
AGGCGCGTAACGGGGTAGAT

Downstream 100 bases:

>100_bases
GAGAGAACACCATGAAACAATCACGTCGTCAATTTTTGAAAAATATGTCTGCCATGGCGGCGACATTTGCGATGCCTAAT
TTCCTTATTGCTCAAAACGC

Product: hypothetical protein

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKFFMLIKRFFTKPSAKIGLGILVSIGFIAGAISWQKFNDLMDHTSTEEFCIGCHSMQQPLEELKQTAHWSNRSGVTATC
SSCHLPHDKTAKYARKVQAVREVFAEFTGKYEEEGAFEKHRQEMAEREWARFAANGSKECKACHSYERMNFDKMSEAARK
AMIPAAAKDQSCMDCHKGVAHHLPKTQVSEGSTSKFDQFVAKAPQADKTYYSKANIALFKDEAMQAQIGQLETAVPVRFV
KAGQGADLVEMTMWRKDKGFGRIWYHQFGKNITDAVLSKEFMQNAPHFTVLAKQEDPLTGLTWQQVSMQVWIAKSQLIED
VKPVWAAAESMYKTQCSTCHRQPEVAHFDSNTWIGLFNGMVGFTNMDKQTSKEVLRYLQLHSSDFEAHSDSK

Sequences:

>Translated_392_residues
MKFFMLIKRFFTKPSAKIGLGILVSIGFIAGAISWQKFNDLMDHTSTEEFCIGCHSMQQPLEELKQTAHWSNRSGVTATC
SSCHLPHDKTAKYARKVQAVREVFAEFTGKYEEEGAFEKHRQEMAEREWARFAANGSKECKACHSYERMNFDKMSEAARK
AMIPAAAKDQSCMDCHKGVAHHLPKTQVSEGSTSKFDQFVAKAPQADKTYYSKANIALFKDEAMQAQIGQLETAVPVRFV
KAGQGADLVEMTMWRKDKGFGRIWYHQFGKNITDAVLSKEFMQNAPHFTVLAKQEDPLTGLTWQQVSMQVWIAKSQLIED
VKPVWAAAESMYKTQCSTCHRQPEVAHFDSNTWIGLFNGMVGFTNMDKQTSKEVLRYLQLHSSDFEAHSDSK
>Mature_392_residues
MKFFMLIKRFFTKPSAKIGLGILVSIGFIAGAISWQKFNDLMDHTSTEEFCIGCHSMQQPLEELKQTAHWSNRSGVTATC
SSCHLPHDKTAKYARKVQAVREVFAEFTGKYEEEGAFEKHRQEMAEREWARFAANGSKECKACHSYERMNFDKMSEAARK
AMIPAAAKDQSCMDCHKGVAHHLPKTQVSEGSTSKFDQFVAKAPQADKTYYSKANIALFKDEAMQAQIGQLETAVPVRFV
KAGQGADLVEMTMWRKDKGFGRIWYHQFGKNITDAVLSKEFMQNAPHFTVLAKQEDPLTGLTWQQVSMQVWIAKSQLIED
VKPVWAAAESMYKTQCSTCHRQPEVAHFDSNTWIGLFNGMVGFTNMDKQTSKEVLRYLQLHSSDFEAHSDSK

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=385, Percent_Identity=36.8831168831169, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1788181, Length=373, Percent_Identity=30.5630026809651, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1788530, Length=188, Percent_Identity=40.4255319148936, Blast_Score=161, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 44448; Mature: 44448

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFMLIKRFFTKPSAKIGLGILVSIGFIAGAISWQKFNDLMDHTSTEEFCIGCHSMQQP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LEELKQTAHWSNRSGVTATCSSCHLPHDKTAKYARKVQAVREVFAEFTGKYEEEGAFEKH
HHHHHHHHCCCCCCCCEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RQEMAEREWARFAANGSKECKACHSYERMNFDKMSEAARKAMIPAAAKDQSCMDCHKGVA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
HHLPKTQVSEGSTSKFDQFVAKAPQADKTYYSKANIALFKDEAMQAQIGQLETAVPVRFV
HCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHE
KAGQGADLVEMTMWRKDKGFGRIWYHQFGKNITDAVLSKEFMQNAPHFTVLAKQEDPLTG
ECCCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
LTWQQVSMQVWIAKSQLIEDVKPVWAAAESMYKTQCSTCHRQPEVAHFDSNTWIGLFNGM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEHHCCC
VGFTNMDKQTSKEVLRYLQLHSSDFEAHSDSK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKFFMLIKRFFTKPSAKIGLGILVSIGFIAGAISWQKFNDLMDHTSTEEFCIGCHSMQQP
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LEELKQTAHWSNRSGVTATCSSCHLPHDKTAKYARKVQAVREVFAEFTGKYEEEGAFEKH
HHHHHHHHCCCCCCCCEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RQEMAEREWARFAANGSKECKACHSYERMNFDKMSEAARKAMIPAAAKDQSCMDCHKGVA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
HHLPKTQVSEGSTSKFDQFVAKAPQADKTYYSKANIALFKDEAMQAQIGQLETAVPVRFV
HCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHE
KAGQGADLVEMTMWRKDKGFGRIWYHQFGKNITDAVLSKEFMQNAPHFTVLAKQEDPLTG
ECCCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
LTWQQVSMQVWIAKSQLIEDVKPVWAAAESMYKTQCSTCHRQPEVAHFDSNTWIGLFNGM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEHHCCC
VGFTNMDKQTSKEVLRYLQLHSSDFEAHSDSK
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]