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The map label for this gene is ubiH [H]

Identifier: 15603590

GI number: 15603590

Start: 1934647

End: 1935852

Strand: Direct

Name: ubiH [H]

Synonym: PM1725

Alternate gene names: 15603590

Gene position: 1934647-1935852 (Clockwise)

Preceding gene: 15603589

Following gene: 15603591

Centisome position: 85.7

GC content: 43.78

Gene sequence:

>1206_bases
ATGCTTGAAGCAGCAAACTACGATGTGATTATTGTAGGTGGGGCGATGACCGGAACAACGCTGGCCCTTGCACTCAGTAG
CAAAACAGCGGGGAAAATGAGAATTGCTGTCCTTGAAAAGCAAGTAACTCATCATCACCAACAAAGTGGCTTTGATGCGC
GTTGTATTGCTTTATCTGACGGTAGTTGCCAGCGTTTTGCGCAAATCCAATTACTTCAGTCACCGCATCTTTGGTCACGT
TTGCAGCCCGTCAGCACCCCCATTCATAAGATCCACGTGTCTGATAAAGGGCATAGTGGTTTGCTGGAATTCAGGGCACA
AGAGTTTAATTTACCCCAATTAGGTGCAGTCATTGAATTAACCCAAGCAGGGCAAATACTCCTCAATGCCATTCAAGAAT
ACACGCATATTGACTACCTTGCACCGATTGAAATTGAAAACATCACACGAAATGACGCGCATGTCGAAATCAAGCTGAAA
AATCACCGCACTTTACGTGGTCAACTTTTAGTTGGCGCAGATGGTACACAATCCTTGGTCGCCAAAGCCGCTAATATCGC
ACAGAAAGTCGTACGCGAATATCGCCAAACAGCGATCATTACCAATATCTTGGTACAACAAGATCATCAGTATCGCGCTT
TTGAGCGTTTTACCGATGAAGGACCGCTTGCTTTATTGCCAATGCAAGACAATCTGATGTCATTAGTTTGGTGCGTTAAA
GATGCTCAACAATTAATGACACTCAATGATCAGGCGTTTTTATCTGCCTTACAAGATCGTTTCGGCTGGCGTCTAGGTAA
ACTGCTACAATGTGGACAACGTTTTACTTATCCATTGAATCTATATCAAGCCGAACAACATATCCAGCCGCGCATTGCTT
TAATTGGCAATGCCGCCCAAACTCTGCATCCGATTGCGGGGCAAGGTTTCAATTTAGGCATTCGCGATGTGATGACCCTC
GCCGATGTGGTCGCCACACATTATCTACAACAAAAAGATATCGGTACTTACGCACATTTACAAGCATATGAAAAACAACG
TCAGTCAGATCAACAGCAAACGCTACGCTTAACTGATGATTTACTTTCTATCTTTGCAAATCATTTATTACCATTACAAT
TTGGACGAACACTCGGCTTAATGACCCTGTCGCAATCAACCTTATTGCGACAACATTTTGCCAAACTGGCATTAGGGTGG
ACTTAA

Upstream 100 bases:

>100_bases
TGCTAATCACCGAATACGGTAATAAAAATCTCACTAGTGCTGTACCAAAAGAAATCGATGAGATTGAAAAATTAATGGCG
GGCAAATAAAGGATCATTTT

Downstream 100 bases:

>100_bases
ACATGAAAACATTTGATCTGGTTATTGTCGGTGGTGGCATGGTTGGGCTCACTCTCGCTGCTCGCCTCGCTAACGCACCA
CTACGCATTGCGCTGATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MLEAANYDVIIVGGAMTGTTLALALSSKTAGKMRIAVLEKQVTHHHQQSGFDARCIALSDGSCQRFAQIQLLQSPHLWSR
LQPVSTPIHKIHVSDKGHSGLLEFRAQEFNLPQLGAVIELTQAGQILLNAIQEYTHIDYLAPIEIENITRNDAHVEIKLK
NHRTLRGQLLVGADGTQSLVAKAANIAQKVVREYRQTAIITNILVQQDHQYRAFERFTDEGPLALLPMQDNLMSLVWCVK
DAQQLMTLNDQAFLSALQDRFGWRLGKLLQCGQRFTYPLNLYQAEQHIQPRIALIGNAAQTLHPIAGQGFNLGIRDVMTL
ADVVATHYLQQKDIGTYAHLQAYEKQRQSDQQQTLRLTDDLLSIFANHLLPLQFGRTLGLMTLSQSTLLRQHFAKLALGW
T

Sequences:

>Translated_401_residues
MLEAANYDVIIVGGAMTGTTLALALSSKTAGKMRIAVLEKQVTHHHQQSGFDARCIALSDGSCQRFAQIQLLQSPHLWSR
LQPVSTPIHKIHVSDKGHSGLLEFRAQEFNLPQLGAVIELTQAGQILLNAIQEYTHIDYLAPIEIENITRNDAHVEIKLK
NHRTLRGQLLVGADGTQSLVAKAANIAQKVVREYRQTAIITNILVQQDHQYRAFERFTDEGPLALLPMQDNLMSLVWCVK
DAQQLMTLNDQAFLSALQDRFGWRLGKLLQCGQRFTYPLNLYQAEQHIQPRIALIGNAAQTLHPIAGQGFNLGIRDVMTL
ADVVATHYLQQKDIGTYAHLQAYEKQRQSDQQQTLRLTDDLLSIFANHLLPLQFGRTLGLMTLSQSTLLRQHFAKLALGW
T
>Mature_401_residues
MLEAANYDVIIVGGAMTGTTLALALSSKTAGKMRIAVLEKQVTHHHQQSGFDARCIALSDGSCQRFAQIQLLQSPHLWSR
LQPVSTPIHKIHVSDKGHSGLLEFRAQEFNLPQLGAVIELTQAGQILLNAIQEYTHIDYLAPIEIENITRNDAHVEIKLK
NHRTLRGQLLVGADGTQSLVAKAANIAQKVVREYRQTAIITNILVQQDHQYRAFERFTDEGPLALLPMQDNLMSLVWCVK
DAQQLMTLNDQAFLSALQDRFGWRLGKLLQCGQRFTYPLNLYQAEQHIQPRIALIGNAAQTLHPIAGQGFNLGIRDVMTL
ADVVATHYLQQKDIGTYAHLQAYEKQRQSDQQQTLRLTDDLLSIFANHLLPLQFGRTLGLMTLSQSTLLRQHFAKLALGW
T

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=280, Percent_Identity=32.1428571428571, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI32967307, Length=298, Percent_Identity=31.2080536912752, Blast_Score=142, Evalue=8e-34,
Organism=Escherichia coli, GI1789274, Length=395, Percent_Identity=43.0379746835443, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI1786883, Length=402, Percent_Identity=31.3432835820896, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789273, Length=347, Percent_Identity=31.9884726224784, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25146631, Length=423, Percent_Identity=26.0047281323877, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6321694, Length=441, Percent_Identity=22.9024943310658, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920760, Length=440, Percent_Identity=26.1363636363636, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 44943; Mature: 44943

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEAANYDVIIVGGAMTGTTLALALSSKTAGKMRIAVLEKQVTHHHQQSGFDARCIALSD
CCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEEECC
GSCQRFAQIQLLQSPHLWSRLQPVSTPIHKIHVSDKGHSGLLEFRAQEFNLPQLGAVIEL
CCHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCHHHHEEH
TQAGQILLNAIQEYTHIDYLAPIEIENITRNDAHVEIKLKNHRTLRGQLLVGADGTQSLV
HHHHHHHHHHHHHHHHCCEECCEEECCCCCCCCEEEEEECCCCEEEEEEEECCCCHHHHH
AKAANIAQKVVREYRQTAIITNILVQQDHQYRAFERFTDEGPLALLPMQDNLMSLVWCVK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHH
DAQQLMTLNDQAFLSALQDRFGWRLGKLLQCGQRFTYPLNLYQAEQHIQPRIALIGNAAQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCHHH
TLHPIAGQGFNLGIRDVMTLADVVATHYLQQKDIGTYAHLQAYEKQRQSDQQQTLRLTDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLSIFANHLLPLQFGRTLGLMTLSQSTLLRQHFAKLALGWT
HHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLEAANYDVIIVGGAMTGTTLALALSSKTAGKMRIAVLEKQVTHHHQQSGFDARCIALSD
CCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCEEEEEECC
GSCQRFAQIQLLQSPHLWSRLQPVSTPIHKIHVSDKGHSGLLEFRAQEFNLPQLGAVIEL
CCHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCHHHHEEH
TQAGQILLNAIQEYTHIDYLAPIEIENITRNDAHVEIKLKNHRTLRGQLLVGADGTQSLV
HHHHHHHHHHHHHHHHCCEECCEEECCCCCCCCEEEEEECCCCEEEEEEEECCCCHHHHH
AKAANIAQKVVREYRQTAIITNILVQQDHQYRAFERFTDEGPLALLPMQDNLMSLVWCVK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHH
DAQQLMTLNDQAFLSALQDRFGWRLGKLLQCGQRFTYPLNLYQAEQHIQPRIALIGNAAQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEECCHHH
TLHPIAGQGFNLGIRDVMTLADVVATHYLQQKDIGTYAHLQAYEKQRQSDQQQTLRLTDD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLSIFANHLLPLQFGRTLGLMTLSQSTLLRQHFAKLALGWT
HHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]