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The map label for this gene is visC [H]

Identifier: 15603591

GI number: 15603591

Start: 1935855

End: 1937024

Strand: Direct

Name: visC [H]

Synonym: PM1726

Alternate gene names: 15603591

Gene position: 1935855-1937024 (Clockwise)

Preceding gene: 15603590

Following gene: 15603593

Centisome position: 85.75

GC content: 42.56

Gene sequence:

>1170_bases
ATGAAAACATTTGATCTGGTTATTGTCGGTGGTGGCATGGTTGGGCTCACTCTCGCTGCTCGCCTCGCTAACGCACCACT
ACGCATTGCGCTGATTGAGGCATTTCCGCCAACAACCCCACTAGAAACAGTTACTCATCGCGTGAGTGCGTTAAACCTGG
CGAGCCAGCATTTACTGACTCAACTTGGTGTCTGGCAAGACATCACCCACATACGAGCAACGGAATACAATGCCATGCAC
GTATGGGAAAAAGATAGCTTTGCTCATATTCATTTTACGACCGCAGGATTAGGCATTTCTCACTTAGGGCATATTGTTGA
AAACCACGTAATTCAGCAAACATTATGGCAAAAAGTGAATCAACAAAAAAATATCGAAATACTCACCGCACTTCCACAAA
CATTAGGCTTAACCGAAAGCCACGCCATGCTCTCACTCAATGATGGTCAAATGGTCGCCACCAAATTACTAGTGGCTGCC
GATGGTGCAAACTCTTGGGTACGCAAACAAGCAAACATTCCACTTGTTTTTAGAGATTATGGACATCATGCATTAGTTTG
TAACGTAGCAACCACAGAACCGCACCAACATTGCGCACGCCAGATATTCTCAAAAGACAGTATCCTTGCCTTCTTACCCT
TACATCAACAACACCTTTGTTCGATAGTTTGGTCACAACCTGGAGAACAAGCAGAGCACCTTGCACAATGTGATGAAGAA
GAATTTAATCGCGCATTATCTGTCGCCTTTGATATGCATCTGGGATTATGTCAAGTTCAAGGGGAAAGACAAGCGATTAA
GTTAACAGCACGTTATGCCCGTGATTTTGCTCAAAATAGAATTGCGCTCGTAGGTGATGCAGCACACACTATTCATCCTC
TAGCAGGTTTAGGGGTCAATTTAGGCTTACAAGATGTTATCGAATTGGCGCGGACAATAGAAGAAAATATAAAAGCAGAT
GTGGATATTGGACAATATCGTTATTTACGCCACTATGAACGTAAACGGAAGAAAGAGACCATGAAAATGTTACTTGTCAT
GCAAGGCTTAAAAGATCTTTTCCATGGAGCTCATCCAATCAAGAAAATGATCAGGGGCATTGGATTGAGTGCAACTGATA
AATTTAGCCTTGTCAAAACAGAATTAATGAAACAAGCCTTAGGATTATAA

Upstream 100 bases:

>100_bases
TACCATTACAATTTGGACGAACACTCGGCTTAATGACCCTGTCGCAATCAACCTTATTGCGACAACATTTTGCCAAACTG
GCATTAGGGTGGACTTAAAC

Downstream 100 bases:

>100_bases
TGACACATATAAAAAAAGCGTGGTTTGATATTTATCGAACCACGCTTTTTTATCCGCTCTCATTTATCCTAGCATGCTGA
TCAGATACTACCTAACAACA

Product: VisC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKTFDLVIVGGGMVGLTLAARLANAPLRIALIEAFPPTTPLETVTHRVSALNLASQHLLTQLGVWQDITHIRATEYNAMH
VWEKDSFAHIHFTTAGLGISHLGHIVENHVIQQTLWQKVNQQKNIEILTALPQTLGLTESHAMLSLNDGQMVATKLLVAA
DGANSWVRKQANIPLVFRDYGHHALVCNVATTEPHQHCARQIFSKDSILAFLPLHQQHLCSIVWSQPGEQAEHLAQCDEE
EFNRALSVAFDMHLGLCQVQGERQAIKLTARYARDFAQNRIALVGDAAHTIHPLAGLGVNLGLQDVIELARTIEENIKAD
VDIGQYRYLRHYERKRKKETMKMLLVMQGLKDLFHGAHPIKKMIRGIGLSATDKFSLVKTELMKQALGL

Sequences:

>Translated_389_residues
MKTFDLVIVGGGMVGLTLAARLANAPLRIALIEAFPPTTPLETVTHRVSALNLASQHLLTQLGVWQDITHIRATEYNAMH
VWEKDSFAHIHFTTAGLGISHLGHIVENHVIQQTLWQKVNQQKNIEILTALPQTLGLTESHAMLSLNDGQMVATKLLVAA
DGANSWVRKQANIPLVFRDYGHHALVCNVATTEPHQHCARQIFSKDSILAFLPLHQQHLCSIVWSQPGEQAEHLAQCDEE
EFNRALSVAFDMHLGLCQVQGERQAIKLTARYARDFAQNRIALVGDAAHTIHPLAGLGVNLGLQDVIELARTIEENIKAD
VDIGQYRYLRHYERKRKKETMKMLLVMQGLKDLFHGAHPIKKMIRGIGLSATDKFSLVKTELMKQALGL
>Mature_389_residues
MKTFDLVIVGGGMVGLTLAARLANAPLRIALIEAFPPTTPLETVTHRVSALNLASQHLLTQLGVWQDITHIRATEYNAMH
VWEKDSFAHIHFTTAGLGISHLGHIVENHVIQQTLWQKVNQQKNIEILTALPQTLGLTESHAMLSLNDGQMVATKLLVAA
DGANSWVRKQANIPLVFRDYGHHALVCNVATTEPHQHCARQIFSKDSILAFLPLHQQHLCSIVWSQPGEQAEHLAQCDEE
EFNRALSVAFDMHLGLCQVQGERQAIKLTARYARDFAQNRIALVGDAAHTIHPLAGLGVNLGLQDVIELARTIEENIKAD
VDIGQYRYLRHYERKRKKETMKMLLVMQGLKDLFHGAHPIKKMIRGIGLSATDKFSLVKTELMKQALGL

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=406, Percent_Identity=30.2955665024631, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI32967307, Length=350, Percent_Identity=30, Blast_Score=129, Evalue=6e-30,
Organism=Escherichia coli, GI1789273, Length=392, Percent_Identity=52.8061224489796, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1786883, Length=395, Percent_Identity=33.1645569620253, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789274, Length=394, Percent_Identity=30.9644670050761, Blast_Score=172, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI25146631, Length=437, Percent_Identity=28.8329519450801, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321694, Length=456, Percent_Identity=25.219298245614, Blast_Score=110, Evalue=5e-25,
Organism=Drosophila melanogaster, GI19920760, Length=433, Percent_Identity=32.7944572748268, Blast_Score=165, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 43356; Mature: 43356

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFDLVIVGGGMVGLTLAARLANAPLRIALIEAFPPTTPLETVTHRVSALNLASQHLLT
CCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
QLGVWQDITHIRATEYNAMHVWEKDSFAHIHFTTAGLGISHLGHIVENHVIQQTLWQKVN
HHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
QQKNIEILTALPQTLGLTESHAMLSLNDGQMVATKLLVAADGANSWVRKQANIPLVFRDY
CCCCCEEEECCHHHHCCCCCCEEEEECCCCEEEHHHEEEECCCCHHHHHCCCCCEEEEEC
GHHALVCNVATTEPHQHCARQIFSKDSILAFLPLHQQHLCSIVWSQPGEQAEHLAQCDEE
CCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHCCCHH
EFNRALSVAFDMHLGLCQVQGERQAIKLTARYARDFAQNRIALVGDAAHTIHPLAGLGVN
HHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCC
LGLQDVIELARTIEENIKADVDIGQYRYLRHYERKRKKETMKMLLVMQGLKDLFHGAHPI
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KKMIRGIGLSATDKFSLVKTELMKQALGL
HHHHHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTFDLVIVGGGMVGLTLAARLANAPLRIALIEAFPPTTPLETVTHRVSALNLASQHLLT
CCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
QLGVWQDITHIRATEYNAMHVWEKDSFAHIHFTTAGLGISHLGHIVENHVIQQTLWQKVN
HHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
QQKNIEILTALPQTLGLTESHAMLSLNDGQMVATKLLVAADGANSWVRKQANIPLVFRDY
CCCCCEEEECCHHHHCCCCCCEEEEECCCCEEEHHHEEEECCCCHHHHHCCCCCEEEEEC
GHHALVCNVATTEPHQHCARQIFSKDSILAFLPLHQQHLCSIVWSQPGEQAEHLAQCDEE
CCEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHCCCHH
EFNRALSVAFDMHLGLCQVQGERQAIKLTARYARDFAQNRIALVGDAAHTIHPLAGLGVN
HHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCCC
LGLQDVIELARTIEENIKADVDIGQYRYLRHYERKRKKETMKMLLVMQGLKDLFHGAHPI
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
KKMIRGIGLSATDKFSLVKTELMKQALGL
HHHHHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]