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The map label for this gene is comF [H]

Identifier: 15603421

GI number: 15603421

Start: 1758601

End: 1759287

Strand: Direct

Name: comF [H]

Synonym: PM1556

Alternate gene names: 15603421

Gene position: 1758601-1759287 (Clockwise)

Preceding gene: 15603420

Following gene: 15603422

Centisome position: 77.9

GC content: 40.9

Gene sequence:

>687_bases
ATGCGGGGATTTGGTTTTTGTTGTGTTCACTGCCAGCAACCGTTAGCCATTGCACATCATGGATTATGTAGTCGCTGTAA
TCAGCAAATCAGACGTTTTGCTTATTGTGGCCATTGTGGTAAGGAATTAACACGAGATGCACTACGTTGTGGGCATTGTT
TACAACATAAAGCCAGTTGGGATCGCATGGTGATCGTTGGTCACTATGTCGATCCCTTATCTTGTTTAATTCACCGTTTT
AAATTCCAACATGCCTTCTTTTTAGACCGTACTTTAGCACGCCTGCTATTATTAGCGCTCTATCATGCAAGACGTACTCA
TGGACTTATTTGGCCAGAAGTACTTTTGCCGGTGCCTTTACATCGTTTACGTCATTGGCAACGTGGTTACAATCAATCTG
CGTTGATTGCAAACTATCTTGCGCATTGGCTAAAGATACCCTGCGATCATGATTTTCTACAGCGTATTAAACATACTCAT
ACGCAACGTGGTTTAAGTGCAACGGAACGAAGAAAAAATTTACGCCACGCATTTCGTCTTCATCCAAAAAGTCAAACGCA
TCGCTATCAATCTGTTGCATTAATTGATGATGTAATTACAACAGGTGCAACGTTGAATGAGTTGGCACTCTTATTAAAAA
AAGCAGGTGTTGAGCATATTCAAGTTTGGGGATTAGCAAAAACGTAA

Upstream 100 bases:

>100_bases
TTACTTTTGCGATGCGTGTCGCAAAAGTAACTTATTCTTTTGCCCTTTTAATATCCTGTGCTTTAGTCTGTAGTCATTTT
ATGTCAAGCAAAGGATACCT

Downstream 100 bases:

>100_bases
GGAAAGATTTATTACTGTAAAAGGTAGAAAAAAAAACGAACTCGGAGTATCATTCTTGACAATCTTACTCAAGTATTCAC
ATTCTTTAGGATAGTTTATG

Product: ComF

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRGFGFCCVHCQQPLAIAHHGLCSRCNQQIRRFAYCGHCGKELTRDALRCGHCLQHKASWDRMVIVGHYVDPLSCLIHRF
KFQHAFFLDRTLARLLLLALYHARRTHGLIWPEVLLPVPLHRLRHWQRGYNQSALIANYLAHWLKIPCDHDFLQRIKHTH
TQRGLSATERRKNLRHAFRLHPKSQTHRYQSVALIDDVITTGATLNELALLLKKAGVEHIQVWGLAKT

Sequences:

>Translated_228_residues
MRGFGFCCVHCQQPLAIAHHGLCSRCNQQIRRFAYCGHCGKELTRDALRCGHCLQHKASWDRMVIVGHYVDPLSCLIHRF
KFQHAFFLDRTLARLLLLALYHARRTHGLIWPEVLLPVPLHRLRHWQRGYNQSALIANYLAHWLKIPCDHDFLQRIKHTH
TQRGLSATERRKNLRHAFRLHPKSQTHRYQSVALIDDVITTGATLNELALLLKKAGVEHIQVWGLAKT
>Mature_228_residues
MRGFGFCCVHCQQPLAIAHHGLCSRCNQQIRRFAYCGHCGKELTRDALRCGHCLQHKASWDRMVIVGHYVDPLSCLIHRF
KFQHAFFLDRTLARLLLLALYHARRTHGLIWPEVLLPVPLHRLRHWQRGYNQSALIANYLAHWLKIPCDHDFLQRIKHTH
TQRGLSATERRKNLRHAFRLHPKSQTHRYQSVALIDDVITTGATLNELALLLKKAGVEHIQVWGLAKT

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=222, Percent_Identity=43.2432432432432, Blast_Score=161, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 26514; Mature: 26514

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFGFCCVHCQQPLAIAHHGLCSRCNQQIRRFAYCGHCGKELTRDALRCGHCLQHKASW
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DRMVIVGHYVDPLSCLIHRFKFQHAFFLDRTLARLLLLALYHARRTHGLIWPEVLLPVPL
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HRLRHWQRGYNQSALIANYLAHWLKIPCDHDFLQRIKHTHTQRGLSATERRKNLRHAFRL
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
HPKSQTHRYQSVALIDDVITTGATLNELALLLKKAGVEHIQVWGLAKT
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEEECCCCC
>Mature Secondary Structure
MRGFGFCCVHCQQPLAIAHHGLCSRCNQQIRRFAYCGHCGKELTRDALRCGHCLQHKASW
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DRMVIVGHYVDPLSCLIHRFKFQHAFFLDRTLARLLLLALYHARRTHGLIWPEVLLPVPL
CCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HRLRHWQRGYNQSALIANYLAHWLKIPCDHDFLQRIKHTHTQRGLSATERRKNLRHAFRL
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
HPKSQTHRYQSVALIDDVITTGATLNELALLLKKAGVEHIQVWGLAKT
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]