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The map label for this gene is trpG_2 [C]

Identifier: 15603328

GI number: 15603328

Start: 1655069

End: 1655659

Strand: Reverse

Name: trpG_2 [C]

Synonym: PM1463

Alternate gene names: 15603328

Gene position: 1655659-1655069 (Counterclockwise)

Preceding gene: 15603333

Following gene: 15603322

Centisome position: 73.34

GC content: 47.55

Gene sequence:

>591_bases
ATGAAACGACTTCTGATCATCAATAATCAAGATTCTTTTACTTACAATTTAGTGGATGTAATCCGTGGCTTAGCGGTGCC
CTTTGACGTGGTTAATGTGCAAGAATTGGATGTGGATGCCGTTGCCAATTACAGCCATATTCTGATTTCCCCTGGTCCTG
ATGTGCCTCGTGCCTATCCACAATTGTTTGCGCTGTTGGAACGCTACCACCAATCCAAATCCATTTTAGGGGTATGCTTG
GGTCATCAAACCCTATGTGAATTTTTTGGCGGTGAATTATACAATTTAGACAAAGTTCGCCACGGGCGTTGCCAACGCCT
ACAAGTGCGGTCAGAATCGGTCTTGTTTCAAGGGCTCCCCCCTGAATTTCAAATTGGCTTATACCACTCTTGGGCAATCC
GTGAACACAATTTCCCTGCGACGCTCACCATCACCGCCCAGTGCGCCGAAGAGGTGGTGATGGCATTCCAGCACAACCAC
TTGCCCATTTACGGTGTGCAATTCCATCCAGAGTCCTTTATGACGGAACATGGCGAACGGCTATTACGCAATTGGTTGGA
ACATCGTTCTCTGCCCTGTACACCGAGTTGA

Upstream 100 bases:

>100_bases
CTACATTTGAAAAAATAAGTGAAAGTTTAACGGAAAATAAACCAAAAATCCGCATTTTCCTTTATACTTTGCCTCTTTCT
CCACAGAATATGGCGCAAAT

Downstream 100 bases:

>100_bases
CACATCTCTCTGACACAAAAAACGGTCAATTTCAATGTGCAAAACATTTTCAAAATTGACCGCACTTTTTCGTTTAGTGG
CGCCTTTTTGGAAAATCAAC

Product: putative anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKRLLIINNQDSFTYNLVDVIRGLAVPFDVVNVQELDVDAVANYSHILISPGPDVPRAYPQLFALLERYHQSKSILGVCL
GHQTLCEFFGGELYNLDKVRHGRCQRLQVRSESVLFQGLPPEFQIGLYHSWAIREHNFPATLTITAQCAEEVVMAFQHNH
LPIYGVQFHPESFMTEHGERLLRNWLEHRSLPCTPS

Sequences:

>Translated_196_residues
MKRLLIINNQDSFTYNLVDVIRGLAVPFDVVNVQELDVDAVANYSHILISPGPDVPRAYPQLFALLERYHQSKSILGVCL
GHQTLCEFFGGELYNLDKVRHGRCQRLQVRSESVLFQGLPPEFQIGLYHSWAIREHNFPATLTITAQCAEEVVMAFQHNH
LPIYGVQFHPESFMTEHGERLLRNWLEHRSLPCTPS
>Mature_196_residues
MKRLLIINNQDSFTYNLVDVIRGLAVPFDVVNVQELDVDAVANYSHILISPGPDVPRAYPQLFALLERYHQSKSILGVCL
GHQTLCEFFGGELYNLDKVRHGRCQRLQVRSESVLFQGLPPEFQIGLYHSWAIREHNFPATLTITAQCAEEVVMAFQHNH
LPIYGVQFHPESFMTEHGERLLRNWLEHRSLPCTPS

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=36.5079365079365, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1787517, Length=202, Percent_Identity=33.6633663366337, Blast_Score=106, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6322638, Length=205, Percent_Identity=31.7073170731707, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324361, Length=209, Percent_Identity=26.7942583732057, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281365319, Length=149, Percent_Identity=32.2147651006711, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22480; Mature: 22480

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLIINNQDSFTYNLVDVIRGLAVPFDVVNVQELDVDAVANYSHILISPGPDVPRAYP
CCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCHHHCCHHHHCCCCEEEEECCCCCCHHHH
QLFALLERYHQSKSILGVCLGHQTLCEFFGGELYNLDKVRHGRCQRLQVRSESVLFQGLP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEECHHHHHCCCHHHEECCCCCEEECCCC
PEFQIGLYHSWAIREHNFPATLTITAQCAEEVVMAFQHNHLPIYGVQFHPESFMTEHGER
CCEEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
LLRNWLEHRSLPCTPS
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKRLLIINNQDSFTYNLVDVIRGLAVPFDVVNVQELDVDAVANYSHILISPGPDVPRAYP
CCEEEEEECCCCEEEHHHHHHHHHCCCCCCCCHHHCCHHHHCCCCEEEEECCCCCCHHHH
QLFALLERYHQSKSILGVCLGHQTLCEFFGGELYNLDKVRHGRCQRLQVRSESVLFQGLP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEECHHHHHCCCHHHEECCCCCEEECCCC
PEFQIGLYHSWAIREHNFPATLTITAQCAEEVVMAFQHNHLPIYGVQFHPESFMTEHGER
CCEEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHH
LLRNWLEHRSLPCTPS
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]