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The map label for this gene is cvgSY [C]

Identifier: 15603245

GI number: 15603245

Start: 1572958

End: 1575546

Strand: Direct

Name: cvgSY [C]

Synonym: PM1380

Alternate gene names: 15603245

Gene position: 1572958-1575546 (Clockwise)

Preceding gene: 15603241

Following gene: 15603249

Centisome position: 69.68

GC content: 40.17

Gene sequence:

>2589_bases
ATGAAACGTTTTTTTACCAGCGCCTTCTTGCCAAAACCCTACAGTGTTCGCTTTCGGCTCGTGATCTTTTTAATCACAGC
CATTTTCCTGATCATTTTTATTAGTGGCACCGCCATTATTGGCTTAAATAGCACTTATAACGCCTTATCCAACCTGCGTG
ATAGTTCATTAAACCAGATGTTTTCCTCAATGACCTTAGGGGTAAAAACTGCACAAATTTCTACTTATGCAAAACGCCTT
ACTCAAACAACACGCGCTTTAGAGTATCAAGAAGAATCCAAAACCTTGGCACATCATGCTGAACAATTACAAATGCTCTT
AACTCAAGCGAAGCAATCTACACCAGAGGACCAACGCTTTGCCAATATCATCTATCACATTGATTTACTGGGAAAAAGTG
TACAAGACTTGCTATTACAAACTCACCAACGTCATATTCTTAACACCACAATCATTAGTGAATTAAACCAAGGGTTGCTC
CACATTCAGCATATTAAAAGACTGGAAAAAAATACCGCACTGCCAGAACAGATCCCTGCCACTTTTTTATCGCAGCTTAA
CCGTATGGAAAAATTAATTGAAGATGCCACCAAAAGTAATTTTTCGACGGGGATTTTTATCAGCATTGAGTCCAATTTTT
TACTCTTCCCTGCAGTTGATTACTTAACCGACATTAACCAAGAACTGGATAAGCTCAAAGCCCTTTTCCCACAGTTGATT
GACAATGCTAAAGCCCTTGAAAAGATCAATTTACGCGTGCAATTCCTCACCTTCCAGATTGATGCTTTGGTGCAACAAAT
TAGCCAACAATATACACAATTGGCGAAAGAAAAAGTGGACAGCGTGGATATTGATTCAGAACAAATTCAACAACGATTAT
CCACACTTACTTTGTCTATTTTGCTCTTTTCGTTATTTACGATTTTATTGATTATTATTCTAGGACAATACATTTATTCC
TTGATCGGCAAACGCTTATATTCCATTACTGATGCGTTAAAACGCTTATCACAAGGCGATAAAAACGTGACGGTACCGCA
ACAACAAACCCAAGATGAAATTGGCGATTTAGCACGGACCTTTGATATTTTTCACCAAAATGTGCTGACCTTAGAGCAAA
CTGACTCATTATTAAAAGAAAAGAGTGAATTATTAGAGCACACGTTTTTAGCCATGCGCGACGGTCTCGCCATTTTTGAC
CAACAACTTAACTTAGTGTCTTACAACGCACAATTTAACACACTACTAGGTGACTTTTTTACGCATACCTCCCCATTAAG
CTTACACACACTGGTGGATTACTTTAATCATAAACACGCTAAGGTAAGCGGCTGGGAACAACCAATTGATCTCGCCTTAC
TGAAACAAATTCGGCAAGCGGAAGATTTCCTTGAAATTGAATATTCACAGCAAGTACTGGAATGGCGGGTTAGTCCATTA
AAAGATGGACTAGTCATCTTTTTAATTGATCGTACACAACGCAAAAAATTAGAAAACGAAATTGCGCACAGTCAAAAAAT
GCGAGCCATCGGTCACCTCACCGGTGGGATTGCGCATGATTTCAATAATTTCTTAGCTGTGATTATTGGTAATTTGGATT
TAATTGATCCGCATGGGCTTGATGAACGCCAAGTCAAACGTCTACAGCGTGCCTTGAAAGCAGCAGAAAATAGCGCAACG
CTGACACAACGCTTGTTAGCCTATGCGCGAAAACAACCGTTACACCCTACAGCTTTAGATATTAATCAACTGGTGATTGA
GTTTAATGATTTGATTAAACACACCATTCCCCCAACGATTAATGTACAACTCGAATTGGGCGAACATTTGCCTTTAGTCT
ATATTGATAAAAACCAGCTCGAAACCGCTTTAGTGAATTTAATTGTCAATGCGAAAGATGCACTCAATCACGAAGGTAAT
ATCATCATTCGCAGCACACAATTAACAGTACAGCGTGCTCATTGCCAAGAGGAGATGGTGCAACTCTCAATCATTGATGA
CGGTTGTGGGATGGATGAGCAAACACAAAAACGGGTATTTGAACCATTCTTCACCACTAAACAAAATGGTCGCGGAAGTG
GCTTGGGCTTATCCATGGTCTATGGTTTTATCCGCCAATCGAAAGGACGTGTACTGATTGAGTCCCAACCTGATCAAGGT
ACCGCTATTCATTTGCAATTGCCAATCGCACAACAAATACAAGATGTATCAGCGTTGACATCCCAACCTCGTCTGAGCTG
TGATACAGCATACCAGATTCTAGTAGTGGAAGATAAAGCCAGTGTACGCGAGACCCTGTCAGAACAATTACATGAAATGG
GCTACCAACCCGTTTTATGTGAGTCAGGTGAACAAGCCCTTGCCTTATTAGAACAAGGACTAACGATTGACTATTTACTC
TCTGATATTATGTTATCCGGCAAATTAACCGGGGTAGATGTCGCAAAATGGGTAAAAACACACTTACCGCAAGTGAAGAT
CCTGTTGATGACAGGGCACACTGAGCAAAGAGAAAAAGCAGAACAATTCCCAGTCCTTGTCAAACCCTTTAAACAAATAG
AATTGCAGCAGAAACTCACCGCACTTTGA

Upstream 100 bases:

>100_bases
TTTTCGAACAAGCTTTTCATAATTATCCTGTATTTTTTCTTGATTCTCCGTACAATGTTTGATGTACCATTCAAGATGAC
AAATAAAGTGCGGTCTATTT

Downstream 100 bases:

>100_bases
GTTATCAAGCATAAAAAAATCCACTTTCTTAACAAAAGTGGATTTTTCTTGCTCAAGAAAAAGGAATATTAGCCTTTTTT
CGCCCCTTGCATATACAGCA

Product: CvgSY

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 862; Mature: 862

Protein sequence:

>862_residues
MKRFFTSAFLPKPYSVRFRLVIFLITAIFLIIFISGTAIIGLNSTYNALSNLRDSSLNQMFSSMTLGVKTAQISTYAKRL
TQTTRALEYQEESKTLAHHAEQLQMLLTQAKQSTPEDQRFANIIYHIDLLGKSVQDLLLQTHQRHILNTTIISELNQGLL
HIQHIKRLEKNTALPEQIPATFLSQLNRMEKLIEDATKSNFSTGIFISIESNFLLFPAVDYLTDINQELDKLKALFPQLI
DNAKALEKINLRVQFLTFQIDALVQQISQQYTQLAKEKVDSVDIDSEQIQQRLSTLTLSILLFSLFTILLIIILGQYIYS
LIGKRLYSITDALKRLSQGDKNVTVPQQQTQDEIGDLARTFDIFHQNVLTLEQTDSLLKEKSELLEHTFLAMRDGLAIFD
QQLNLVSYNAQFNTLLGDFFTHTSPLSLHTLVDYFNHKHAKVSGWEQPIDLALLKQIRQAEDFLEIEYSQQVLEWRVSPL
KDGLVIFLIDRTQRKKLENEIAHSQKMRAIGHLTGGIAHDFNNFLAVIIGNLDLIDPHGLDERQVKRLQRALKAAENSAT
LTQRLLAYARKQPLHPTALDINQLVIEFNDLIKHTIPPTINVQLELGEHLPLVYIDKNQLETALVNLIVNAKDALNHEGN
IIIRSTQLTVQRAHCQEEMVQLSIIDDGCGMDEQTQKRVFEPFFTTKQNGRGSGLGLSMVYGFIRQSKGRVLIESQPDQG
TAIHLQLPIAQQIQDVSALTSQPRLSCDTAYQILVVEDKASVRETLSEQLHEMGYQPVLCESGEQALALLEQGLTIDYLL
SDIMLSGKLTGVDVAKWVKTHLPQVKILLMTGHTEQREKAEQFPVLVKPFKQIELQQKLTAL

Sequences:

>Translated_862_residues
MKRFFTSAFLPKPYSVRFRLVIFLITAIFLIIFISGTAIIGLNSTYNALSNLRDSSLNQMFSSMTLGVKTAQISTYAKRL
TQTTRALEYQEESKTLAHHAEQLQMLLTQAKQSTPEDQRFANIIYHIDLLGKSVQDLLLQTHQRHILNTTIISELNQGLL
HIQHIKRLEKNTALPEQIPATFLSQLNRMEKLIEDATKSNFSTGIFISIESNFLLFPAVDYLTDINQELDKLKALFPQLI
DNAKALEKINLRVQFLTFQIDALVQQISQQYTQLAKEKVDSVDIDSEQIQQRLSTLTLSILLFSLFTILLIIILGQYIYS
LIGKRLYSITDALKRLSQGDKNVTVPQQQTQDEIGDLARTFDIFHQNVLTLEQTDSLLKEKSELLEHTFLAMRDGLAIFD
QQLNLVSYNAQFNTLLGDFFTHTSPLSLHTLVDYFNHKHAKVSGWEQPIDLALLKQIRQAEDFLEIEYSQQVLEWRVSPL
KDGLVIFLIDRTQRKKLENEIAHSQKMRAIGHLTGGIAHDFNNFLAVIIGNLDLIDPHGLDERQVKRLQRALKAAENSAT
LTQRLLAYARKQPLHPTALDINQLVIEFNDLIKHTIPPTINVQLELGEHLPLVYIDKNQLETALVNLIVNAKDALNHEGN
IIIRSTQLTVQRAHCQEEMVQLSIIDDGCGMDEQTQKRVFEPFFTTKQNGRGSGLGLSMVYGFIRQSKGRVLIESQPDQG
TAIHLQLPIAQQIQDVSALTSQPRLSCDTAYQILVVEDKASVRETLSEQLHEMGYQPVLCESGEQALALLEQGLTIDYLL
SDIMLSGKLTGVDVAKWVKTHLPQVKILLMTGHTEQREKAEQFPVLVKPFKQIELQQKLTAL
>Mature_862_residues
MKRFFTSAFLPKPYSVRFRLVIFLITAIFLIIFISGTAIIGLNSTYNALSNLRDSSLNQMFSSMTLGVKTAQISTYAKRL
TQTTRALEYQEESKTLAHHAEQLQMLLTQAKQSTPEDQRFANIIYHIDLLGKSVQDLLLQTHQRHILNTTIISELNQGLL
HIQHIKRLEKNTALPEQIPATFLSQLNRMEKLIEDATKSNFSTGIFISIESNFLLFPAVDYLTDINQELDKLKALFPQLI
DNAKALEKINLRVQFLTFQIDALVQQISQQYTQLAKEKVDSVDIDSEQIQQRLSTLTLSILLFSLFTILLIIILGQYIYS
LIGKRLYSITDALKRLSQGDKNVTVPQQQTQDEIGDLARTFDIFHQNVLTLEQTDSLLKEKSELLEHTFLAMRDGLAIFD
QQLNLVSYNAQFNTLLGDFFTHTSPLSLHTLVDYFNHKHAKVSGWEQPIDLALLKQIRQAEDFLEIEYSQQVLEWRVSPL
KDGLVIFLIDRTQRKKLENEIAHSQKMRAIGHLTGGIAHDFNNFLAVIIGNLDLIDPHGLDERQVKRLQRALKAAENSAT
LTQRLLAYARKQPLHPTALDINQLVIEFNDLIKHTIPPTINVQLELGEHLPLVYIDKNQLETALVNLIVNAKDALNHEGN
IIIRSTQLTVQRAHCQEEMVQLSIIDDGCGMDEQTQKRVFEPFFTTKQNGRGSGLGLSMVYGFIRQSKGRVLIESQPDQG
TAIHLQLPIAQQIQDVSALTSQPRLSCDTAYQILVVEDKASVRETLSEQLHEMGYQPVLCESGEQALALLEQGLTIDYLL
SDIMLSGKLTGVDVAKWVKTHLPQVKILLMTGHTEQREKAEQFPVLVKPFKQIELQQKLTAL

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=29.0836653386454, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=27.9166666666667, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1788713, Length=480, Percent_Identity=23.3333333333333, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1790300, Length=271, Percent_Identity=24.7232472324723, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=24.4813278008299, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 97848; Mature: 97848

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFFTSAFLPKPYSVRFRLVIFLITAIFLIIFISGTAIIGLNSTYNALSNLRDSSLNQM
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
FSSMTLGVKTAQISTYAKRLTQTTRALEYQEESKTLAHHAEQLQMLLTQAKQSTPEDQRF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ANIIYHIDLLGKSVQDLLLQTHQRHILNTTIISELNQGLLHIQHIKRLEKNTALPEQIPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
TFLSQLNRMEKLIEDATKSNFSTGIFISIESNFLLFPAVDYLTDINQELDKLKALFPQLI
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DNAKALEKINLRVQFLTFQIDALVQQISQQYTQLAKEKVDSVDIDSEQIQQRLSTLTLSI
CCHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLFSLFTILLIIILGQYIYSLIGKRLYSITDALKRLSQGDKNVTVPQQQTQDEIGDLART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FDIFHQNVLTLEQTDSLLKEKSELLEHTFLAMRDGLAIFDQQLNLVSYNAQFNTLLGDFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCHHHHHHHHHH
THTSPLSLHTLVDYFNHKHAKVSGWEQPIDLALLKQIRQAEDFLEIEYSQQVLEWRVSPL
HCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDGLVIFLIDRTQRKKLENEIAHSQKMRAIGHLTGGIAHDFNNFLAVIIGNLDLIDPHGL
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEECCCCC
DERQVKRLQRALKAAENSATLTQRLLAYARKQPLHPTALDINQLVIEFNDLIKHTIPPTI
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
NVQLELGEHLPLVYIDKNQLETALVNLIVNAKDALNHEGNIIIRSTQLTVQRAHCQEEMV
EEEEEECCCCCEEEECCHHHHHHHHHHHHCCHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
QLSIIDDGCGMDEQTQKRVFEPFFTTKQNGRGSGLGLSMVYGFIRQSKGRVLIESQPDQG
EEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
TAIHLQLPIAQQIQDVSALTSQPRLSCDTAYQILVVEDKASVRETLSEQLHEMGYQPVLC
CEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCEEE
ESGEQALALLEQGLTIDYLLSDIMLSGKLTGVDVAKWVKTHLPQVKILLMTGHTEQREKA
CCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHH
EQFPVLVKPFKQIELQQKLTAL
HHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRFFTSAFLPKPYSVRFRLVIFLITAIFLIIFISGTAIIGLNSTYNALSNLRDSSLNQM
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
FSSMTLGVKTAQISTYAKRLTQTTRALEYQEESKTLAHHAEQLQMLLTQAKQSTPEDQRF
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ANIIYHIDLLGKSVQDLLLQTHQRHILNTTIISELNQGLLHIQHIKRLEKNTALPEQIPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
TFLSQLNRMEKLIEDATKSNFSTGIFISIESNFLLFPAVDYLTDINQELDKLKALFPQLI
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
DNAKALEKINLRVQFLTFQIDALVQQISQQYTQLAKEKVDSVDIDSEQIQQRLSTLTLSI
CCHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLFSLFTILLIIILGQYIYSLIGKRLYSITDALKRLSQGDKNVTVPQQQTQDEIGDLART
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
FDIFHQNVLTLEQTDSLLKEKSELLEHTFLAMRDGLAIFDQQLNLVSYNAQFNTLLGDFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCHHHHHHHHHH
THTSPLSLHTLVDYFNHKHAKVSGWEQPIDLALLKQIRQAEDFLEIEYSQQVLEWRVSPL
HCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KDGLVIFLIDRTQRKKLENEIAHSQKMRAIGHLTGGIAHDFNNFLAVIIGNLDLIDPHGL
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEECCCCC
DERQVKRLQRALKAAENSATLTQRLLAYARKQPLHPTALDINQLVIEFNDLIKHTIPPTI
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
NVQLELGEHLPLVYIDKNQLETALVNLIVNAKDALNHEGNIIIRSTQLTVQRAHCQEEMV
EEEEEECCCCCEEEECCHHHHHHHHHHHHCCHHHCCCCCCEEEEEHHHHHHHHHHHHHHH
QLSIIDDGCGMDEQTQKRVFEPFFTTKQNGRGSGLGLSMVYGFIRQSKGRVLIESQPDQG
EEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCC
TAIHLQLPIAQQIQDVSALTSQPRLSCDTAYQILVVEDKASVRETLSEQLHEMGYQPVLC
CEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCEEE
ESGEQALALLEQGLTIDYLLSDIMLSGKLTGVDVAKWVKTHLPQVKILLMTGHTEQREKA
CCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHH
EQFPVLVKPFKQIELQQKLTAL
HHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA