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The map label for this gene is ompR [H]

Identifier: 15603241

GI number: 15603241

Start: 1568196

End: 1568927

Strand: Direct

Name: ompR [H]

Synonym: PM1376

Alternate gene names: 15603241

Gene position: 1568196-1568927 (Clockwise)

Preceding gene: 15603234

Following gene: 15603245

Centisome position: 69.47

GC content: 40.98

Gene sequence:

>732_bases
ATGGATATACAAATGCAACAAAATACTTCTCTTCTTGTCATTGATGATGATGTTCAAGTTTGTGAATTGCTTACCGATAT
TTTTGAGGAACATGGCTATACTGTTATGACGGCTCAAACCGGTCAGCAAGCGTTAGCTTTGTTGCAATCGACTCCGCACT
TTTCATTAATTTTTCTTGATTTAATTCTGCCTGATGTAAATGGATTAATTCTCTTACAGCGTTTAAAAAGCCTGACCACT
GCCCCTGTGATTATGTTAAGTGGGCTAGATTCTGAATCCGATATTGTTGTTGGCTTAGAAATGGGTGCTGATGACTACAT
CTCCAAACCCTTTTATCCTCGCGTGGTCGTTGCAAGAGCGAAAGTCGCGTTACGTCGCCATCAGCCACAACCTTTTTCAA
CTAGCGCCTCACATCAAGGTTTTACTTTTCATCATTGGGTGCTAGATACACAAAATCGGAAATTATATTCGCCACAAAAA
GTGGATATTGAGCTGACGCAAGGAGAATACACCTTATTACACGCCTTAGTTTCTCATGCACAAAAAGTTCTTTCTCGTGA
AAAGTTACTTGAACTGACACACACGGAAAGCTTAGAAATTTTTGACCGCACTGTCGATGTGCTCATTATGCGGTTACGTA
AAAAAATTGAGCCTAACCCCAAGGCACCAACCTATATTCAAACTGTTCGCGGCATGGGTTATTTATTTGCCGTCGCGGTT
GAGCGCTGTTAA

Upstream 100 bases:

>100_bases
GCCAATACGCATAACTACCTCATCGTTTTAGATTTTGTTTATTGATGAATACTCTTTCTGTTAGAAATTATATATACTTA
AAAAATAATCTATTTAAGGC

Downstream 100 bases:

>100_bases
TGTCGCATGTTTAACCACAAATAATAAGCCCCCTCCCAAACTCAGGAGGGGGAATCAGGTAATTACTTCACAGTCCAACC
TTTATAATCTTTAATGTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDIQMQQNTSLLVIDDDVQVCELLTDIFEEHGYTVMTAQTGQQALALLQSTPHFSLIFLDLILPDVNGLILLQRLKSLTT
APVIMLSGLDSESDIVVGLEMGADDYISKPFYPRVVVARAKVALRRHQPQPFSTSASHQGFTFHHWVLDTQNRKLYSPQK
VDIELTQGEYTLLHALVSHAQKVLSREKLLELTHTESLEIFDRTVDVLIMRLRKKIEPNPKAPTYIQTVRGMGYLFAVAV
ERC

Sequences:

>Translated_243_residues
MDIQMQQNTSLLVIDDDVQVCELLTDIFEEHGYTVMTAQTGQQALALLQSTPHFSLIFLDLILPDVNGLILLQRLKSLTT
APVIMLSGLDSESDIVVGLEMGADDYISKPFYPRVVVARAKVALRRHQPQPFSTSASHQGFTFHHWVLDTQNRKLYSPQK
VDIELTQGEYTLLHALVSHAQKVLSREKLLELTHTESLEIFDRTVDVLIMRLRKKIEPNPKAPTYIQTVRGMGYLFAVAV
ERC
>Mature_243_residues
MDIQMQQNTSLLVIDDDVQVCELLTDIFEEHGYTVMTAQTGQQALALLQSTPHFSLIFLDLILPDVNGLILLQRLKSLTT
APVIMLSGLDSESDIVVGLEMGADDYISKPFYPRVVVARAKVALRRHQPQPFSTSASHQGFTFHHWVLDTQNRKLYSPQK
VDIELTQGEYTLLHALVSHAQKVLSREKLLELTHTESLEIFDRTVDVLIMRLRKKIEPNPKAPTYIQTVRGMGYLFAVAV
ERC

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=39.7435897435897, Blast_Score=170, Evalue=6e-44,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=34.5991561181435, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.9565217391304, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=33.8842975206612, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI2367329, Length=249, Percent_Identity=35.7429718875502, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=34.8936170212766, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=235, Percent_Identity=34.0425531914894, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=32.2033898305085, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=33.9130434782609, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=33.1896551724138, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=34.3347639484979, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790552, Length=236, Percent_Identity=32.2033898305085, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.7510917030568, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=29.8245614035088, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790437, Length=105, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27499; Mature: 27499

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQMQQNTSLLVIDDDVQVCELLTDIFEEHGYTVMTAQTGQQALALLQSTPHFSLIFLD
CCCEECCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHH
LILPDVNGLILLQRLKSLTTAPVIMLSGLDSESDIVVGLEMGADDYISKPFYPRVVVARA
HHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHCCCCCCHHHHHHH
KVALRRHQPQPFSTSASHQGFTFHHWVLDTQNRKLYSPQKVDIELTQGEYTLLHALVSHA
HHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCEECCCCEEEEEEECCHHHHHHHHHHHH
QKVLSREKLLELTHTESLEIFDRTVDVLIMRLRKKIEPNPKAPTYIQTVRGMGYLFAVAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHH
ERC
HCC
>Mature Secondary Structure
MDIQMQQNTSLLVIDDDVQVCELLTDIFEEHGYTVMTAQTGQQALALLQSTPHFSLIFLD
CCCEECCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCCHHHHHHH
LILPDVNGLILLQRLKSLTTAPVIMLSGLDSESDIVVGLEMGADDYISKPFYPRVVVARA
HHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCHHHCCCCCCHHHHHHH
KVALRRHQPQPFSTSASHQGFTFHHWVLDTQNRKLYSPQKVDIELTQGEYTLLHALVSHA
HHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCEECCCCEEEEEEECCHHHHHHHHHHHH
QKVLSREKLLELTHTESLEIFDRTVDVLIMRLRKKIEPNPKAPTYIQTVRGMGYLFAVAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHH
ERC
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]