Click here to switch to the map view.

The map label for this gene is lsrR [H]

Identifier: 15603138

GI number: 15603138

Start: 1465620

End: 1466585

Strand: Reverse

Name: lsrR [H]

Synonym: PM1273

Alternate gene names: 15603138

Gene position: 1466585-1465620 (Counterclockwise)

Preceding gene: 15603146

Following gene: 15603137

Centisome position: 64.97

GC content: 42.13

Gene sequence:

>966_bases
ATGACAGACAATAAATTTGAAACCCTTGATACTAGCCAAACGATGAGTGAAGAGGAGCTACTTGCACGAATTGCGTGGTT
CTATTACCACGATAATCTCACACAAGGGGAAATTGGTGATAAATTGGGTTTACCTCGTTTAAAAGTATCACGTTTATTAG
AAAAAGGACGACAACAAGGCATTATTAAAGTCCAGATTAACTCACGTTTTACCGGTTGCCTTGAATTAGAAGAAGCACTG
AAAGAACATTTTCAGTTAAAACACATACGTATTTTGCCGGCGTTAGAAAAAAACGAAATCAATGAACGTTTAGGGATTGG
GGCATCACAAATGCTGATGTCGATGCTAAAGCCCAATCAGCGCTTAGCGATTGGTTTTGGTGAAACCATTATGCAAACGA
TTAAGCACAGTAATGAGTTTATTACACACAATCATTTGAAGTTGATTACGTTATCTGGTGGAGTGGGACCTTATATGAAA
GGGATAGGTCAGTTGGATGGCTCTTGTTCCGTCAGTATTATTCCCGCACCTTTACGCGCTTCTTCGATTGAAGCAGCAAA
GCTCTTTAAACGAGAAGCTTGTGTCAGAGATATTATGCTTGCGGCCTGTCATGCCGATGCTGCCATTGTTGGCATCGGCG
CCACGCGCCAGAAAGGGCAAGCCACATTGCTGCGCACTGGTTACATTACCGAAGAAAAACAACGTTTAATACGTGAACAA
GGTGCGGTAGGTGATATTCTCGGCTACTTTATGCAAAAAGACGGACAGCTCCAGCCGGATATGCCCTTACACGAAGAACT
GATTAGCGTCACGCTCGATAATTTGAAAAAAATCCCAAATGTGATTGGCATTGCGGGTGGTGAAGACAAAGTCGAAGCCA
TCCTAAGTGCCTTATATGGACAACATATTAATTCATTAGTAACGGAAGAAAAAACAGCTCGAATGATGTTAGCCGCCTTA
GTGTGA

Upstream 100 bases:

>100_bases
AAAAAGTGATCTTCCTCACAATTAAATAAAAAAGTAAAATGAACAGTTGATAATAAAATTAAACAAATGAATAATGCATT
AAGCCATTGAGAATATAACT

Downstream 100 bases:

>100_bases
TGCGATAAGAGCTCCTTTTACTTCCTTACAGCGAAAGGAGAAATCAATGAGCAATCAATATCTTATGGCACTTGATGCTG
GGACCGGGAGTGTACGTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTDNKFETLDTSQTMSEEELLARIAWFYYHDNLTQGEIGDKLGLPRLKVSRLLEKGRQQGIIKVQINSRFTGCLELEEAL
KEHFQLKHIRILPALEKNEINERLGIGASQMLMSMLKPNQRLAIGFGETIMQTIKHSNEFITHNHLKLITLSGGVGPYMK
GIGQLDGSCSVSIIPAPLRASSIEAAKLFKREACVRDIMLAACHADAAIVGIGATRQKGQATLLRTGYITEEKQRLIREQ
GAVGDILGYFMQKDGQLQPDMPLHEELISVTLDNLKKIPNVIGIAGGEDKVEAILSALYGQHINSLVTEEKTARMMLAAL
V

Sequences:

>Translated_321_residues
MTDNKFETLDTSQTMSEEELLARIAWFYYHDNLTQGEIGDKLGLPRLKVSRLLEKGRQQGIIKVQINSRFTGCLELEEAL
KEHFQLKHIRILPALEKNEINERLGIGASQMLMSMLKPNQRLAIGFGETIMQTIKHSNEFITHNHLKLITLSGGVGPYMK
GIGQLDGSCSVSIIPAPLRASSIEAAKLFKREACVRDIMLAACHADAAIVGIGATRQKGQATLLRTGYITEEKQRLIREQ
GAVGDILGYFMQKDGQLQPDMPLHEELISVTLDNLKKIPNVIGIAGGEDKVEAILSALYGQHINSLVTEEKTARMMLAAL
V
>Mature_320_residues
TDNKFETLDTSQTMSEEELLARIAWFYYHDNLTQGEIGDKLGLPRLKVSRLLEKGRQQGIIKVQINSRFTGCLELEEALK
EHFQLKHIRILPALEKNEINERLGIGASQMLMSMLKPNQRLAIGFGETIMQTIKHSNEFITHNHLKLITLSGGVGPYMKG
IGQLDGSCSVSIIPAPLRASSIEAAKLFKREACVRDIMLAACHADAAIVGIGATRQKGQATLLRTGYITEEKQRLIREQG
AVGDILGYFMQKDGQLQPDMPLHEELISVTLDNLKKIPNVIGIAGGEDKVEAILSALYGQHINSLVTEEKTARMMLAALV

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=307, Percent_Identity=57.328990228013, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI87082414, Length=332, Percent_Identity=23.4939759036145, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35544; Mature: 35413

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNKFETLDTSQTMSEEELLARIAWFYYHDNLTQGEIGDKLGLPRLKVSRLLEKGRQQG
CCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
IIKVQINSRFTGCLELEEALKEHFQLKHIRILPALEKNEINERLGIGASQMLMSMLKPNQ
EEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCC
RLAIGFGETIMQTIKHSNEFITHNHLKLITLSGGVGPYMKGIGQLDGSCSVSIIPAPLRA
EEEEECCHHHHHHHHCCCCEEEECCEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCC
SSIEAAKLFKREACVRDIMLAACHADAAIVGIGATRQKGQATLLRTGYITEEKQRLIREQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHC
GAVGDILGYFMQKDGQLQPDMPLHEELISVTLDNLKKIPNVIGIAGGEDKVEAILSALYG
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHH
QHINSLVTEEKTARMMLAALV
HHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TDNKFETLDTSQTMSEEELLARIAWFYYHDNLTQGEIGDKLGLPRLKVSRLLEKGRQQG
CCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
IIKVQINSRFTGCLELEEALKEHFQLKHIRILPALEKNEINERLGIGASQMLMSMLKPNQ
EEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCC
RLAIGFGETIMQTIKHSNEFITHNHLKLITLSGGVGPYMKGIGQLDGSCSVSIIPAPLRA
EEEEECCHHHHHHHHCCCCEEEECCEEEEEECCCCCHHHHHHHCCCCCCEEEEECCCCCC
SSIEAAKLFKREACVRDIMLAACHADAAIVGIGATRQKGQATLLRTGYITEEKQRLIREQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHC
GAVGDILGYFMQKDGQLQPDMPLHEELISVTLDNLKKIPNVIGIAGGEDKVEAILSALYG
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHH
QHINSLVTEEKTARMMLAALV
HHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]