Click here to switch to the map view.

The map label for this gene is rsmC

Identifier: 15602823

GI number: 15602823

Start: 1130740

End: 1131726

Strand: Reverse

Name: rsmC

Synonym: PM0958

Alternate gene names: 15602823

Gene position: 1131726-1130740 (Counterclockwise)

Preceding gene: 15602826

Following gene: 15602817

Centisome position: 50.13

GC content: 41.95

Gene sequence:

>987_bases
GTGATTTCTCTTGAAAGCCAAGTTCTACAGCGTCATCTTTCTTTTTTTGAGCATAAATCAGTTTTATTTGCGGGGGGTAT
TAATGATCAGTTTCCTCAGCAAGTGCCGGCGCGCAGCGTGAAGGTGTGGAGTTGGTATTTTGATTATGCCAAAAGCAAAA
GTGCGGTCGATTTTTCATTAACTTGTGAAGAAAAAGCGGATCTCATGGTGTTTTACTGGACTAAAAACAAGCAAGAAGTG
CAATTCCAACTTATGCAATTACTCGCTCAAGCTCCGATTGGTCAAGAAATGTTGATTGTAGGTGAAAATCGCTGCGGAGT
GCGTTCTGTGGAAAAAATGCTCGATGCTTATGGCGATATTGCTAAAATTGACTCGGCAAGGCGTTGTGGGTTATATCATT
TTTGTTTAAAAAACACACCGCACTTTGCGTTAGCAGATTATTGGAAAACTTATCAGCATCCTCGCTTAGGTGATTTGCGT
ATTTACAGTTTACCGGGGGTATTTAGTGCGAATGAGTTGGATGTTGGCACAGATTTGTTGCTTTCAACCTTAGATCAACC
GGTGCGAGGAAAGGTGTTAGATTTAGGTTGTGGTGCGGGGGTGATTGGTGCTTATATTAAACAGCAATATCCTCAAGTTG
AGCTGACTATGGCGGATATTCATGCGCTAGCTTTAGCTTCTAGCCAACGGACTTTAGCTGAGAACCAGTTAGAGGCAGAG
GTGATCGCCAGTGACGTTTTTTCTAATGTGGCAGGAAAATTCGATCTGATTATTTCAAATCCCCCTTTTCACGATGGCAT
TGATACGGCTTATCGTGCTGTCAGTGAATTAATTATGCAAGCGAAATGGCATTTAGTACCAGGCGGTGAATTACGCATTG
TGGCGAATGCATTCTTGCCTTATCCTGATTTATTGGATCAACATTTTGGCTCACATTGTGTGTTAGCCAAAACCACTAAA
TTTAAAGTGTATTCTGTCCGCGGCTAA

Upstream 100 bases:

>100_bases
TGTAATAGAAGATCTCGTCTATTCATGCTATTTCTTCATCGTTGCGTGTTTTTCCTTTATAATGCGTCAATTTTAACGAA
TAACAGATAGGATTAACAGC

Downstream 100 bases:

>100_bases
ACAAGTACGACTCACTTTCGGGTGAATGCATTAAAGTTTAGATAAATCGGCTTAGAAAAAAGAAGGCAGACGGTAAAGTC
TGCCTTTCTTACCTTTTATT

Product: 16S ribosomal RNA m2G1207 methyltransferase

Products: NA

Alternate protein names: 16S rRNA m2G1207 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rsmC

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MISLESQVLQRHLSFFEHKSVLFAGGINDQFPQQVPARSVKVWSWYFDYAKSKSAVDFSLTCEEKADLMVFYWTKNKQEV
QFQLMQLLAQAPIGQEMLIVGENRCGVRSVEKMLDAYGDIAKIDSARRCGLYHFCLKNTPHFALADYWKTYQHPRLGDLR
IYSLPGVFSANELDVGTDLLLSTLDQPVRGKVLDLGCGAGVIGAYIKQQYPQVELTMADIHALALASSQRTLAENQLEAE
VIASDVFSNVAGKFDLIISNPPFHDGIDTAYRAVSELIMQAKWHLVPGGELRIVANAFLPYPDLLDQHFGSHCVLAKTTK
FKVYSVRG

Sequences:

>Translated_328_residues
MISLESQVLQRHLSFFEHKSVLFAGGINDQFPQQVPARSVKVWSWYFDYAKSKSAVDFSLTCEEKADLMVFYWTKNKQEV
QFQLMQLLAQAPIGQEMLIVGENRCGVRSVEKMLDAYGDIAKIDSARRCGLYHFCLKNTPHFALADYWKTYQHPRLGDLR
IYSLPGVFSANELDVGTDLLLSTLDQPVRGKVLDLGCGAGVIGAYIKQQYPQVELTMADIHALALASSQRTLAENQLEAE
VIASDVFSNVAGKFDLIISNPPFHDGIDTAYRAVSELIMQAKWHLVPGGELRIVANAFLPYPDLLDQHFGSHCVLAKTTK
FKVYSVRG
>Mature_328_residues
MISLESQVLQRHLSFFEHKSVLFAGGINDQFPQQVPARSVKVWSWYFDYAKSKSAVDFSLTCEEKADLMVFYWTKNKQEV
QFQLMQLLAQAPIGQEMLIVGENRCGVRSVEKMLDAYGDIAKIDSARRCGLYHFCLKNTPHFALADYWKTYQHPRLGDLR
IYSLPGVFSANELDVGTDLLLSTLDQPVRGKVLDLGCGAGVIGAYIKQQYPQVELTMADIHALALASSQRTLAENQLEAE
VIASDVFSNVAGKFDLIISNPPFHDGIDTAYRAVSELIMQAKWHLVPGGELRIVANAFLPYPDLLDQHFGSHCVLAKTTK
FKVYSVRG

Specific function: Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmC family

Homologues:

Organism=Escherichia coli, GI1790830, Length=328, Percent_Identity=49.0853658536585, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI87082206, Length=195, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMC_PASMU (Q9CM79)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245895.1
- HSSP:   Q58292
- ProteinModelPortal:   Q9CM79
- SMR:   Q9CM79
- GeneID:   1244305
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0958
- NMPDR:   fig|272843.1.peg.958
- HOGENOM:   HBG296757
- OMA:   TGKFKVY
- ProtClustDB:   PRK09489
- BioCyc:   PMUL272843:PM0958-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01862
- InterPro:   IPR002052
- InterPro:   IPR013675
- InterPro:   IPR007848

Pfam domain/function: PF05175 MTS; PF08468 MTS_N

EC number: =2.1.1.172

Molecular weight: Translated: 36772; Mature: 36772

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLESQVLQRHLSFFEHKSVLFAGGINDQFPQQVPARSVKVWSWYFDYAKSKSAVDFSL
CCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCEEEEE
TCEEKADLMVFYWTKNKQEVQFQLMQLLAQAPIGQEMLIVGENRCGVRSVEKMLDAYGDI
EECCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCH
AKIDSARRCGLYHFCLKNTPHFALADYWKTYQHPRLGDLRIYSLPGVFSANELDVGTDLL
HHHCCHHHCCEEEHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHH
LSTLDQPVRGKVLDLGCGAGVIGAYIKQQYPQVELTMADIHALALASSQRTLAENQLEAE
HHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHH
VIASDVFSNVAGKFDLIISNPPFHDGIDTAYRAVSELIMQAKWHLVPGGELRIVANAFLP
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCC
YPDLLDQHFGSHCVLAKTTKFKVYSVRG
CHHHHHHHCCCEEEEEEECEEEEEEECC
>Mature Secondary Structure
MISLESQVLQRHLSFFEHKSVLFAGGINDQFPQQVPARSVKVWSWYFDYAKSKSAVDFSL
CCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCEEEEE
TCEEKADLMVFYWTKNKQEVQFQLMQLLAQAPIGQEMLIVGENRCGVRSVEKMLDAYGDI
EECCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCH
AKIDSARRCGLYHFCLKNTPHFALADYWKTYQHPRLGDLRIYSLPGVFSANELDVGTDLL
HHHCCHHHCCEEEHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHH
LSTLDQPVRGKVLDLGCGAGVIGAYIKQQYPQVELTMADIHALALASSQRTLAENQLEAE
HHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHH
VIASDVFSNVAGKFDLIISNPPFHDGIDTAYRAVSELIMQAKWHLVPGGELRIVANAFLP
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCC
YPDLLDQHFGSHCVLAKTTKFKVYSVRG
CHHHHHHHCCCEEEEEEECEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100