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The map label for this gene is udk

Identifier: 15602817

GI number: 15602817

Start: 1123338

End: 1123988

Strand: Reverse

Name: udk

Synonym: PM0952

Alternate gene names: 15602817

Gene position: 1123988-1123338 (Counterclockwise)

Preceding gene: 15602823

Following gene: 15602816

Centisome position: 49.79

GC content: 38.25

Gene sequence:

>651_bases
ATGTCAAACTCATCAACACCATCTTGTATTATTATTGCCATCGCTGGGGCTTCAGCATCAGGAAAAAGCTTAATTGCCTC
AACTGTTCATCGAGAGTTGTGTGATGAGCTAGGTTGCGAAGAAATTGGCATTATTTCCGAAGACTCTTATTATAAAGATC
AAAGTCATTTGGATATGGAAGATCGAATTAAAACCAACTATGATCATCCTAATTCTATGGATAGACACCTTTTAATTGAA
CACCTCAAAGCACTCAAATCTGGTCAACCGGTTGATATTCCCGTCTATAGCTACGTTGAGCATACTCGAACCAATCAAGT
CCAACACTTTGAACCTAAAAAAGTGATCATTCTGGAAGGGATTTTATTGCTTACTGATGAAAAATTGCGTGATGAAGTCA
GTGTCTCTGTTTTTGTCGATACACCACTGGATATTTGTTTTATTCGTCGCTTACAACGTGACATGAAAGAACGTGGTCGA
AGTTTAGAATCGGTAGTGGAGCAGTATCGTAAAACAGTGCGTCCCATGTTTTTACAGTTTATTGAGCCCTCTAAACAATA
TGCTGATATCGTGATCCCGCGAGGTGGTAAAAATCGAATTGCCATTAATATGTTAAAAGCACAGATTAGACAACTTTTGG
GAAAACGTTAA

Upstream 100 bases:

>100_bases
AATATCTTCTTTATTTTATCTGTCTTGGAATTGTGCTATTAAAAGTGGATTTTTTTCTTTATAATTTGTCGATCAAAACA
ACGCTTTTTTAGGGATAGCT

Downstream 100 bases:

>100_bases
CAGTAAGGAGCTGAGAATGAGATTATGTGATACTGATATTGAACGTTATTTAGATGATGGCATTATCGCGTTAACCCCTC
GACCGAGTAATGACAAAATT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSNSSTPSCIIIAIAGASASGKSLIASTVHRELCDELGCEEIGIISEDSYYKDQSHLDMEDRIKTNYDHPNSMDRHLLIE
HLKALKSGQPVDIPVYSYVEHTRTNQVQHFEPKKVIILEGILLLTDEKLRDEVSVSVFVDTPLDICFIRRLQRDMKERGR
SLESVVEQYRKTVRPMFLQFIEPSKQYADIVIPRGGKNRIAINMLKAQIRQLLGKR

Sequences:

>Translated_216_residues
MSNSSTPSCIIIAIAGASASGKSLIASTVHRELCDELGCEEIGIISEDSYYKDQSHLDMEDRIKTNYDHPNSMDRHLLIE
HLKALKSGQPVDIPVYSYVEHTRTNQVQHFEPKKVIILEGILLLTDEKLRDEVSVSVFVDTPLDICFIRRLQRDMKERGR
SLESVVEQYRKTVRPMFLQFIEPSKQYADIVIPRGGKNRIAINMLKAQIRQLLGKR
>Mature_215_residues
SNSSTPSCIIIAIAGASASGKSLIASTVHRELCDELGCEEIGIISEDSYYKDQSHLDMEDRIKTNYDHPNSMDRHLLIEH
LKALKSGQPVDIPVYSYVEHTRTNQVQHFEPKKVIILEGILLLTDEKLRDEVSVSVFVDTPLDICFIRRLQRDMKERGRS
LESVVEQYRKTVRPMFLQFIEPSKQYADIVIPRGGKNRIAINMLKAQIRQLLGKR

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI57863312, Length=216, Percent_Identity=37.037037037037, Blast_Score=156, Evalue=1e-38,
Organism=Homo sapiens, GI301129207, Length=216, Percent_Identity=37.037037037037, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI18699734, Length=219, Percent_Identity=36.0730593607306, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI13899253, Length=216, Percent_Identity=36.1111111111111, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI209863022, Length=153, Percent_Identity=32.6797385620915, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI87082034, Length=205, Percent_Identity=71.219512195122, Blast_Score=317, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17539892, Length=209, Percent_Identity=36.8421052631579, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17539894, Length=209, Percent_Identity=36.8421052631579, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71981181, Length=215, Percent_Identity=33.0232558139535, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324339, Length=195, Percent_Identity=32.3076923076923, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28573516, Length=209, Percent_Identity=36.3636363636364, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28573514, Length=209, Percent_Identity=36.3636363636364, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28573512, Length=209, Percent_Identity=36.3636363636364, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI45550449, Length=209, Percent_Identity=36.3636363636364, Blast_Score=146, Evalue=8e-36,
Organism=Drosophila melanogaster, GI221458995, Length=230, Percent_Identity=35.6521739130435, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24649624, Length=228, Percent_Identity=35.0877192982456, Blast_Score=139, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_PASMU (Q9CM85)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245889.1
- ProteinModelPortal:   Q9CM85
- SMR:   Q9CM85
- GeneID:   1244299
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0952
- NMPDR:   fig|272843.1.peg.952
- HOGENOM:   HBG527126
- OMA:   DQIGVIA
- ProtClustDB:   PRK05480
- BioCyc:   PMUL272843:PM0952-MONOMER
- BRENDA:   2.7.1.48
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 24681; Mature: 24550

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSSTPSCIIIAIAGASASGKSLIASTVHRELCDELGCEEIGIISEDSYYKDQSHLDME
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
DRIKTNYDHPNSMDRHLLIEHLKALKSGQPVDIPVYSYVEHTRTNQVQHFEPKKVIILEG
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEC
ILLLTDEKLRDEVSVSVFVDTPLDICFIRRLQRDMKERGRSLESVVEQYRKTVRPMFLQF
CCEECCHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IEPSKQYADIVIPRGGKNRIAINMLKAQIRQLLGKR
HCCCCHHCEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNSSTPSCIIIAIAGASASGKSLIASTVHRELCDELGCEEIGIISEDSYYKDQSHLDME
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
DRIKTNYDHPNSMDRHLLIEHLKALKSGQPVDIPVYSYVEHTRTNQVQHFEPKKVIILEG
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEC
ILLLTDEKLRDEVSVSVFVDTPLDICFIRRLQRDMKERGRSLESVVEQYRKTVRPMFLQF
CCEECCHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IEPSKQYADIVIPRGGKNRIAINMLKAQIRQLLGKR
HCCCCHHCEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100