Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 15602591

GI number: 15602591

Start: 856476

End: 857288

Strand: Reverse

Name: dapB

Synonym: PM0726

Alternate gene names: 15602591

Gene position: 857288-856476 (Counterclockwise)

Preceding gene: 15602592

Following gene: 15602588

Centisome position: 37.98

GC content: 46.0

Gene sequence:

>813_bases
ATGACATTACGTGTGGCAATCGTCGGTGCTGGCGGCAGAATGGGGCGCCAATTGATTCAAGCGGTAAGTGAAACGGAGGG
GGTCGTCTTAGGGGCTGCCTTTGAACGTCAAGGTTCATCTTTATTAGGGGCAGATGCCGGAGAATTAGCCAATGTGGGTC
ATCTTGGTGTACAGATTACCGATGATTTAGCCAGCCAACAAGACCAGTTTGATCTCTTGATTGATTTTACTCGTCCAGAG
GGAACTTTAGCGCATCTTGCATTTTGTGTGGCACAGCATAAAAATATGGTAATTGGTACAACAGGCTTTGATGATGACGG
AAAAGCGAAAATTCAGCAAGCTGCAGACAGTATTGGCATTGTGTTCGCATCTAATTTTAGCGTAGGAGTGAATTTGGTGT
TCAAGTTGTTAGAAAAAGCCGCCAAAGTCATGGGCGATTATTGTGATATTGAAATTATTGAAGCCCACCATCGTCATAAG
GTGGATGCGCCTTCAGGGACCGCGTTATCGATGGGAGAACATATTGCAAAAACGCTAGGACGGGATCTGAAAACACATGG
CGTATTTACCCGTGACGGTATTACGGGTGAACGTAAACGGGATGAGATTGGCTTTGCCACAATACGGGCAAGTGATGTTG
TCGGTGAGCACAGTGTGTGGTTTGCGGACATTGGTGAGCGTGTTGAAATTGCTCATAAAGCCACAAGTCGCATGACCTTT
GCCAAAGGAGCAGTACGTGCAGCGAAGTGGCTTGCACAAAAAGAAAAGGGGCTATTTGATATGACCGATGTGCTCGATTT
AAATCAGCTTTAA

Upstream 100 bases:

>100_bases
AATGTATAGTGGTATCGGGGAAATGACCCCACTTATCTCGAAATGATGCCATTGTGGTGGTCATTTCATATAGCGCGATA
TAGCAAAAGGGGATAATAAT

Downstream 100 bases:

>100_bases
CCGAATTCAGCAGAGGTAAACCTCTGCTGTTTTGTTAGAGTTGAGCGGTTTTATAGATCAATTCAGCAATAGTTTGCGCT
TGCATTTTTTCCATAATATG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTLRVAIVGAGGRMGRQLIQAVSETEGVVLGAAFERQGSSLLGADAGELANVGHLGVQITDDLASQQDQFDLLIDFTRPE
GTLAHLAFCVAQHKNMVIGTTGFDDDGKAKIQQAADSIGIVFASNFSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHK
VDAPSGTALSMGEHIAKTLGRDLKTHGVFTRDGITGERKRDEIGFATIRASDVVGEHSVWFADIGERVEIAHKATSRMTF
AKGAVRAAKWLAQKEKGLFDMTDVLDLNQL

Sequences:

>Translated_270_residues
MTLRVAIVGAGGRMGRQLIQAVSETEGVVLGAAFERQGSSLLGADAGELANVGHLGVQITDDLASQQDQFDLLIDFTRPE
GTLAHLAFCVAQHKNMVIGTTGFDDDGKAKIQQAADSIGIVFASNFSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHK
VDAPSGTALSMGEHIAKTLGRDLKTHGVFTRDGITGERKRDEIGFATIRASDVVGEHSVWFADIGERVEIAHKATSRMTF
AKGAVRAAKWLAQKEKGLFDMTDVLDLNQL
>Mature_269_residues
TLRVAIVGAGGRMGRQLIQAVSETEGVVLGAAFERQGSSLLGADAGELANVGHLGVQITDDLASQQDQFDLLIDFTRPEG
TLAHLAFCVAQHKNMVIGTTGFDDDGKAKIQQAADSIGIVFASNFSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKV
DAPSGTALSMGEHIAKTLGRDLKTHGVFTRDGITGERKRDEIGFATIRASDVVGEHSVWFADIGERVEIAHKATSRMTFA
KGAVRAAKWLAQKEKGLFDMTDVLDLNQL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=269, Percent_Identity=69.8884758364312, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_PASMU (P57867)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245663.1
- ProteinModelPortal:   P57867
- SMR:   P57867
- GeneID:   1244073
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0726
- NMPDR:   fig|272843.1.peg.726
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   PMUL272843:PM0726-MONOMER
- BRENDA:   1.3.1.26
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29027; Mature: 28896

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRVAIVGAGGRMGRQLIQAVSETEGVVLGAAFERQGSSLLGADAGELANVGHLGVQIT
CEEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCCCCCHHHCCCCCCCEEEE
DDLASQQDQFDLLIDFTRPEGTLAHLAFCVAQHKNMVIGTTGFDDDGKAKIQQAADSIGI
HHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCEEE
VFASNFSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKVDAPSGTALSMGEHIAKTLG
EEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCCCHHHHHHHHHHHC
RDLKTHGVFTRDGITGERKRDEIGFATIRASDVVGEHSVWFADIGERVEIAHKATSRMTF
CCHHHCCCEECCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEECCCCHHHHHHHHHHHHHH
AKGAVRAAKWLAQKEKGLFDMTDVLDLNQL
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
>Mature Secondary Structure 
TLRVAIVGAGGRMGRQLIQAVSETEGVVLGAAFERQGSSLLGADAGELANVGHLGVQIT
EEEEEEEECCHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCCCCCHHHCCCCCCCEEEE
DDLASQQDQFDLLIDFTRPEGTLAHLAFCVAQHKNMVIGTTGFDDDGKAKIQQAADSIGI
HHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCEEE
VFASNFSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKVDAPSGTALSMGEHIAKTLG
EEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCCCHHHHHHHHHHHC
RDLKTHGVFTRDGITGERKRDEIGFATIRASDVVGEHSVWFADIGERVEIAHKATSRMTF
CCHHHCCCEECCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEECCCCHHHHHHHHHHHHHH
AKGAVRAAKWLAQKEKGLFDMTDVLDLNQL
HHHHHHHHHHHHHHHCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100